Results 281 to 290 of about 262,733 (310)
MUC13 is a crucial player in YAP1-β-catenin survival complex mediated cancer metastasis. [PDF]
Malik S +3 more
europepmc +1 more source
Macrophage β-catenin-Ihh axis induces hepatic stellate cell activation and fibrosis in metabolic dysfunction-associated steatohepatitis. [PDF]
Zhang R +9 more
europepmc +1 more source
Elevated expression of CK19, Ki67, and β-Catenin as prognostic biomarkers in hepatocellular carcinoma. [PDF]
Yu H, Wu J, Gao L.
europepmc +1 more source
β-Catenin stabilization protects against alveolar hemorrhage through amphiregulin- and BATF-mediated Tregs. [PDF]
Mason F +11 more
europepmc +1 more source
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2018
Selective disruption of protein-protein interactions by small molecules is important for probing the structure and dynamic aspects of the cellular network. It can also provide new therapeutic targets. β-Catenin of the canonical Wnt signaling pathway uses the same positively charged groove to bind with T-cell factor (Tcf), cadherin, and adenomatous ...
openaire +1 more source
Selective disruption of protein-protein interactions by small molecules is important for probing the structure and dynamic aspects of the cellular network. It can also provide new therapeutic targets. β-Catenin of the canonical Wnt signaling pathway uses the same positively charged groove to bind with T-cell factor (Tcf), cadherin, and adenomatous ...
openaire +1 more source
2018
The dysregulation of proteinâ€"protein interaction (PPI) networks has been implicated in many diseases. Designing therapeutic small-molecule inhibitors of these interactions is a challenging field for medicinal chemistry. This work advances the techniques for discovering more potent PPI inhibitors through integration of computational and biochemical ...
openaire +1 more source
The dysregulation of proteinâ€"protein interaction (PPI) networks has been implicated in many diseases. Designing therapeutic small-molecule inhibitors of these interactions is a challenging field for medicinal chemistry. This work advances the techniques for discovering more potent PPI inhibitors through integration of computational and biochemical ...
openaire +1 more source
Intestinal Crypt Fission and Expression of Î'-Catenin in the Small Intestine of Humans
Gastroenterology, 2017Zenab M. Dudhwala +4 more
openaire +1 more source
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
Signal Transduction and Targeted Therapy, 2022Jiaqi Liu, Yuanyuan Li, Xiaojun Zhang
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