Results 311 to 320 of about 1,680,534 (386)

Resveratrol Prevents Breast Cancer Metastasis by Inhibiting Wnt/β-Catenin Pathway-Mediated Epithelial-Mesenchymal Transition. [PDF]

Pharmaceuticals (Basel)
Fang X, Ma E, Wang R, Zhang J, Tang Y, Chen J, Zhu W, Wo D, Ren DN.   +8 more
europepmc   +1 more source

Prognostic Impact of Histologic Subtypes in Mismatch Repair‐Deficient/Microsatellite Instability‐High Colorectal Cancer: A Single‐Center Retrospective Study of 1127 Stage 0–IV Patients

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Deficient mismatch repair/microsatellite instability‐High (dMMR/MSI‐H) colorectal cancer (CRC) generally confers a favorable survival yet is paradoxically enriched for poorly differentiated (Por) histology, which is linked to aggressive behavior.
Tomoyuki Momma, Hirokazu Okayama, Sohei Hayashishita, Hiroya Suzuki, Masanori Katagata, Takuro Matsumoto, Daisuke Ujiie, Shun Chida, Wataru Sakamoto, Koji Kono   +9 more
wiley   +1 more source

Targeting sorting nexin 3 to treat pulmonary fibrosis by dual modulating Wnt/β-catenin signaling. [PDF]

Cell Death Dis
Ma D, Yu W, Zhou H, Lin R, Sun X, Peng M, Lin C, Du H, Li Y, Liang H, Sun D, Liu P, Lu J.   +12 more
europepmc   +1 more source

Data from CCN6 Suppresses Metaplastic Breast Carcinoma by Antagonizing Wnt/β-Catenin Signaling to Inhibit EZH2-Driven EMT

Maria E. Gonzalez, Bryce Brophy, Ahmad Eido, Adele Elisabetta Leonetti, Sabra Djomehri, Giuseppina Augimeri, Nicholas J. Carruthers, Raymond G. Cavalcante, Francesca Giordano, Sebastiano Andò, Alexey I. Nesvizhskii, Eric R. Fearon, Celina G. Kleer   +12 more
openalex   +1 more source

Faculty Opinions recommendation of Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct β-catenin phosphorylation.

, 2012
Alfonso Martínez Arias
openalex   +2 more sources

Differential Prognostic Impact of Prior Cholecystectomy Between Proximal and Distal Colorectal Cancer: A 12‐Year Retrospective Cohort Study of 3487 Consecutive Patients

Annals of Gastroenterological Surgery, EarlyView.
In this retrospective cohort of 3487 patients with CRC, history of CCY was associated with significantly worse prognosis in patients with proximal CRC but not in those with distal CRC. This differential prognostic impact showed a statistically significant interaction between tumor location and history of CCY and remained robust after PSM.
Masashi Tsunematsu, Koichiro Haruki, Kazuhiro Yanamoto, Takuo Takehana, Shunta Ishizaki, Mitsuru Yanagaki, Yoshihiro Shirai, Kenei Furukawa, Shinji Onda, Toru Ikegami   +9 more
wiley   +1 more source

Targeting CXCR6 Disrupts β-Catenin Signaling and Enhances Sorafenib Response in Hepatocellular Carcinoma. [PDF]

Cancers (Basel)
Reeves M, Chambers A, Shrestha A, Duarte S, Zarrinpar A, Malany S, Peddibhotla S.   +6 more
europepmc   +1 more source

Data from PDGFRβ Signaling Cooperates with β-Catenin to Modulate c-Abl and Biologic Behavior of Desmoid-Type Fibromatosis

Jia Hu, Meera Hameed, Narasimhan P. Agaram, Karissa Whiting, Li‐Xuan Qin, Anthony M. Villano, Rachael O’Connor, Julian M. Rozenberg, Sonia Cohen, Katherine Prendergast, Sara Kryeziu, Richard L. White, Mitchell C. Posner, Nicholas D. Socci, Mrinal M. Gounder, Samuel Singer, Aimeé M. Crago   +16 more
openalex   +1 more source

Intestinal polyposis in mice with a dominant stable mutation of the β‐catenin gene

EMBO Journal, 1999
N. Harada, Y. Tamai, T. Ishikawa, B. Sauer, K. Takaku, M. Oshima, M. Taketo   +6 more
semanticscholar   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source