Optimized Yamanaka factors combined with TERT gene therapy for enhanced anti-aging effects. [PDF]
Jiang M, Xu Q, Wu Z.
europepmc +1 more source
Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos +3 more
wiley +1 more source
Immobilized β-galactosidase BgaC from Bifidobacterium adolescentis retains stability and activity during repeated cycles of use. [PDF]
Mulualem DM +4 more
europepmc +1 more source
Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers +16 more
wiley +1 more source
ABSTRACT The production of plant‐based meat analogues from various protein sources is an emerging application worldwide, driven by growing population and health concerns. Many microorganisms during fermentation play a crucial role in fermented plant‐based meat alternatives, together with structuring and analytical approaches in terms of nutritional ...
Fatma Beyza Özpınar +4 more
wiley +1 more source
Division of the large and multifunctional glycoside hydrolase family 2: high functional specificity and biochemical assays in the uncharacterized subfamilies. [PDF]
Lebreton A +9 more
europepmc +1 more source
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu +6 more
wiley +1 more source
Diminished and Altered Cellular Senescence Response in Delayed Wound Healing of Aging
Acute wound healing in young skin is supported by a transient population of senescent fibroblasts with proreparative, ECM‐remodeling functions. Aging disrupts both the induction and functional identity of these cells, contributing to delayed wound closure and impaired tissue repair.
Maria Shvedova +5 more
wiley +1 more source
Probiotic Engraftment of Akkermansia muciniphila in an In Vitro Synthetic Microbial Community. [PDF]
Berkhout MD +4 more
europepmc +1 more source

