Results 251 to 260 of about 4,834 (282)

Senolytic Treatment With Fisetin Reverses Age‐Related Endothelial Dysfunction Partially Mediated by SASP Factor CXCL12

Aging Cell, Volume 25, Issue 5, May 2026.
Single‐cell transcriptomics identifies that oral, intermittent fisetin supplementation improves endothelial function by targeting senescent endothelial cell‐derived senescence‐associated secretory phenotype (SASP) factors and CXCL12 in old animals. The SASP and specifically CXCL12 were found to drive age‐related endothelial dysfunction by promoting ...
Sophia A. Mahoney, Krystyna Mazan‐Mamczarz, Dimitrios Tsitsipatis, Nicholas S. VanDongen, Charnae’ Henry‐Smith, Ada N. Okereke, Rachel Munk, Sanna Darvish, Kevin O. Murray, Supriyo De, Myriam Gorospe, Douglas R. Seals, Matthew J. Rossman, Allison B. Herman, Zachary S. Clayton   +14 more
wiley   +1 more source

Whole genome sequence analysis of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> KL101 and comparative genomics with BB12. [PDF]

J Anim Sci Technol
Kim K, Lee J, Kang SJ, Oh S.
europepmc   +1 more source

Aging‐Driven Immunosuppression: The Role of Tregs in the Ovarian Tumor Microenvironment

Aging Cell, Volume 25, Issue 5, May 2026.
In the aged ovarian TME, cancer cells exhibit increased succinate production. Elevated extracellular succinate activates the SUCNR1 receptor on Tregs, promoting their recruitment and contributing to an immunosuppressive environment. This leads to diminished anti‐tumor T cell responses and reduced survival.
Mary P. Udumula, Anjaly KM, Faraz Rashid, Mohammad Nematullah, Harshit Singh, Tanya Bhardwaj, Miriana Hijaz, Shailendra Giri, Eduardo N. Chini, Heather M. Gibson, Ramandeep Rattan   +10 more
wiley   +1 more source

Synthesis of an N-Galactosyl Norbornane Aziridine and its Potent Mixed Inhibition of Aspergillus oryzae β-Galactosidase. [PDF]

Chembiochem
McCormack A, Gavin R, Bols M, Murphy PV.
europepmc   +1 more source

Could the estrobolome have a role in endometriosis pathogenesis and infertility? A systematic review. [PDF]

BMC Womens Health
Saponara S, Scicchitano F, D'Alterio MN, Chilà C, Daniilidis A, Vitale SG, Angioni S.   +6 more
europepmc   +1 more source

Advances in Liposomal Drug Delivery: Multidirectional Perspectives on Overcoming Biological Barriers. [PDF]

Pharmaceutics
Sobol Ż, Chiczewski R, Wątróbska-Świetlikowska D.   +2 more
europepmc   +1 more source

Draft genome sequence of Talaromyces trachyspermus, a biocontrol fungus isolated from broomrape. [PDF]

G3 (Bethesda)
Hemmati R, Dolatabadian A, Saeedi S, Batley J.   +3 more
europepmc   +1 more source

Galactooligosaccharide Production Using Immobilized <i>Aspergillus oryzae</i> β-Galactosidase, Part I: Characterization and Influence of Reaction Conditions. [PDF]

Int J Mol Sci
Antošová M, Adamíková JK, Polakovič M.   +2 more
europepmc   +1 more source

Recombinant production of Paenibacillus wynnii β-galactosidase with Komagataella phaffii. [PDF]

Microb Cell Fact
Bechtel A, Seitl I, Pross E, Hetzel F, Keutgen M, Fischer L.   +5 more
europepmc   +1 more source