Results 61 to 70 of about 4,834 (282)

Safety of a change in the conditions of use of galacto‐oligosaccharides as a novel food ingredient in food supplements pursuant to Regulation (EU) 2015/2283

EFSA Journal, 2021
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the change in the conditions of use of galacto‐oligosaccharides (GOS) as a novel food (NF) pursuant to ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, John Kearney, Alexandre Maciuk, Inge Mangelsdorf, Harry J McArdle, Androniki Naska, Carmen Pelaez, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Rosangela Marchelli, Monika Neuhäuser‐Berthold, Morten Poulsen, Miguel Prieto Maradona, Josef Rudolf Schlatter, Henk van Loveren, Paolo Colombo, Helle Katrine Knutsen   +26 more
doaj   +1 more source

Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines [PDF]

, 2017
Activity-based protein profiling has emerged as a powerful tool for visualizing glycosidases in complex biological samples. Several configurational cyclophellitol isomers have been shown to display high selectivity as probes for glycosidases processing ...
Adriaan J. Minnaard, Atsumi, Bogdan I. Florea, Chi-Lin Kuo, Davies, Davies, Eva J. van Rooden, Evans, Franck, Gideon J. Davies, Gijsbert A. van der Marel, Hansen, Herman S. Overkleeft, Jasper W. van de Sande, Jeroen D. C. Codée, Jianbing Jiang, Jiang, Jiang, Johannes M. F. G. Aerts, Kallemeijn, Kuharev, Larsbrink, Le Carré, Liu, Long, Luzi, Marta Artola, Nagano, Ohtsubo, Sybrin P. Schröder, Thomas J. M. Beenakker, Tomino, Tony, van Weely, Wendy A. Offen, Willems, Willems, Withers, Witte, Wouter W. Kallemeijn   +39 more
core   +3 more sources

Optimised N-acetyl-d-lactosamine synthesis using Thermus thermophilus β-galactosidase in bio-solvents

Tetrahedron, 2013
Synthesis of N-acetyl-D-lactosamine (Gal-β[1→4]GlcNAc, LacNAc) catalyzed by β-galactosidase from Thermus thermophilus (TTP0042) is affected by side reactions that give as result very low yields (about 20%) of LAcNAc when the reaction is performed in buffer.
Sandoval, Manuel, Civera, Concepción, Berenguer, José, García-Blanco, Franscico, Hernáiz, María J.   +4 more
openaire   +2 more sources

Galactooligosaccharides formation during enzymatic hydrolysis of lactose: towards a prebiotic enriched milk [PDF]

, 2014
The formation of galacto-oligosaccharides (GOS) in skim milk during the treatment with several commercial β-galactosidases (Bacillus circulans, Kluyveromyces lactis and Aspergillus oryzae) was analyzed in detail, at 4°C and 40°C.
Ballesteros Olmo, Antonio, Fernández Arrojo, Lucía, Plou Gasca, Francisco José, Rodríguez-Colinas, Bárbara   +3 more
core   +2 more sources

Structural Bioinformatics Analysis of GH42 Family β-Galactosidases

Shipin gongye ke-ji
Objective: To elucidate the structural basis underlying the diverse extremophilic catalytic properties of β-galactosidases in the GH42 glycoside hydrolase family, enzymes with resolved crystal structures were systematically analyzed to reveal the ...
Mingfei GUO, Yuming ZHENG, Haiyang GU, Lushan WANG, Yining DONG   +4 more
doaj   +1 more source

Biochemical characterization of digestive carbohydrases from Xanthogaleruca luteola and inhibition of its α-amylase by inhibitors extracted from the common bean [PDF]

, 2011
Xanthogaleruca luteola Müll. (Col.: Chrysomelidae) is a major urban insect pest on elm trees in Iran. Digestion in the alimentary canal of the elm leaf beetle is facilitated by some carbohydrases which are responsible for the digestion of ...
Ghadamyari Mohammad, Moghadam Mahdavi Maryam, Saiidi Fetemeh, Sharifi Mahbobeh   +3 more
core   +1 more source

Biotechnology of Lactulose Production: Progress, Challenges, and Prospects

Техника и технология пищевых производств, 2023
Lactulose is a prebiotic that has found a wide application in medicine and food industry. Commercial lactulose is usually synthesized by isomerization in alkaline media at high temperatures.
Svetlana A. Ryabtseva, Andrey G. Khramtsov, Maria A. Shpak, Alexey D. Lodygin, Georgy S. Anisimov, Serafima N. Sazanova, Yulia A. Tabakova   +6 more
doaj   +1 more source

Construction of a flocculent Saccharomyces cerevisiae strain secreting high levels of Aspergillus niger β-galactosidase [PDF]

, 2002
A flocculent Saccharomyces cerevisiae strain secreting Aspergillus niger β-galactosidase activity was constructed by transforming S. cerevisiae NCYC869-A3 strain with plasmid pVK1.1 harboring the A. niger β-galactosidase gene, lacA, under the control
Domingues, Lucília, Lima, Nelson, Penttilä, M., Teixeira, J. A.   +3 more
core   +1 more source

EXTRACTION AND CHARACTERIZATION OF Î’-GALACTOSIDASE ENZYME FROM ZIZIPHUS SPINA-CHRISTI FOR FOOD APPLICATIONS

International Journal of Advanced Research
Galactosidaseis an industrially important enzymewitha number of applications in dairy, fermentation, and food industries. The study was carried out to extract and characterize the galactosidase enzymefromZiziphusspina-christi,a therapeutic herb. The enzyme was studied for pH, temperature sensitivity, and heavy metal effects on enzyme activity.
Omar Almuharib, Anmar Nazar Hasan
openaire   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source