Results 51 to 60 of about 23,485 (167)
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Journal of Translational Medicine, 2012 Background High systemic estrogen levels contribute to breast cancer risk for postmenopausal women, whereas low levels contribute to osteoporosis risk. Except for obesity, determinants of non-ovarian systemic estrogen levels are undefined.
Flores Roberto +8 more
doaj +1 more source
Future Postharvest and Food, EarlyView.The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja +3 more
wiley +1 more source
High-throughput β-galactosidase and β-glucuronidase Assays Using Fluorogenic Substrates
Bio-Protocol, 2013 β-galactosidase and β-glucuronidase enzymes are commonly used as reporters for gene expression from gene promoter-lacZ or uidA fusions (respectively). The protocol described here is a high-throughput alternative to the commonly used Miller assay (Miller,
Josh Ramsay
doaj +1 more source
Presence of benznidazole conjugated metabolites in urine identified by β-glucuronidase treatment
Brazilian Journal of Pharmaceutical Sciences, 2020 Chagas disease is a serious public health problem in Latin America and, due to migration, in other non-endemic regions. Benznidazole (BNZ) is first choice drug in pediatric therapeutics. However, little is known regarding its metabolism in humans.
María Elena Marson +5 more
doaj +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Acephate is an organophosphate insecticide widely used. This pesticide can be metabolized into methamidophos, a molecule highly toxic. Both have demonstrated the ability to promote serious toxic effects on nontarget organisms and have been identified in surface waters around the world. Therefore, it is important to understand their behavior in
Mariana Laiz Silva de Lima +3 more
wiley +1 more source
PLoS ONE, 2016 Crohn's disease, an incurable chronic inflammatory bowel disease, has been attributed to both genetic predisposition and environmental factors. A dysbiosis of the gut microbiota, observed in numerous patients but also in at least one hundred unaffected ...
Karine Gloux, Jamila Anba-Mondoloni
doaj +1 more source
Measuring Faecal Epi-Androsterone as an Indicator of Gonadal Activity in Spotted Hyenas (Crocuta crocuta). [PDF]
PLoS ONE, 2015 Enzyme immunoassays (EIA) that measure faecal testosterone metabolites (fTM) are useful tools to monitor gonadal activity. The aim of this study was to validate an "in-house" epiandrosterone EIA to monitor fTM in spotted hyenas. FTM were characterised in
Susanne Pribbenow +5 more
doaj +1 more source
Medicine Advances, EarlyView.Based on the observational analysis of UK Biobank clinical data, urinary tract obstruction showed a significant negative association with breast cancer risk, accompanied by substantially lower systemic estradiol levels in individuals with obstruction.
Hailu Wang +7 more
wiley +1 more source
Pest Management Science, EarlyView.The cabbage stem flea beetle (Psylliodes chrysocephala) is a major pest of winter oilseed rape (Brassica napus). We tested B. napus and Sinapis alba seedlings for feeding resistance and underlying chemical defenses. S. alba was least damaged, while metabolite profiles revealed resistance‐linked compounds, highlighting breeding potential for insect ...
Daniel Rüde +4 more
wiley +1 more source