Results 171 to 180 of about 1,516,213 (305)

Probing the Unfolded Configurations of a β-Hairpin Using Sketch-Map [PDF]

, 2015
Albert Ardèvol, Gareth A. Tribello, Michele Ceriotti, Michele Parrinello   +3 more
openalex   +1 more source

Programming Next‐Generation Synthetic Biosensors by Genetic Circuit Design

Advanced Science, EarlyView.
Synthetic biology enables genetic circuit‐based biosensing to detect diverse targets, process signals, and transduce them into readable outputs or intracellular regulatory activities. However, field deployment and real‐world application of such synthetic biosensors face considerable challenges in sensitivity, specificity, speed, stability, and ...
Yuanli Gao, Cheng Huang, Jiaxuan Deng, Lei Wang, Baojun Wang   +4 more
wiley   +1 more source

Effects of N-Terminal Residues on the Assembly of Constrained β-Hairpin Peptides Derived from Aβ

, 2020
Tuan D. Samdin, Michał Wierzbicki, Adam G. Kreutzer, William J. Howitz, Mike Valenzuela, Alberto Smith, Victoria Sahrai, Nicholas L. Truex, Matthew Klun, James S. Nowick   +9 more
openalex   +2 more sources

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

Immunity, 2017
J. H. Lee, Raiees Andrabi, Ching-Yao Su, A. Yasmeen, J. Julien, L. Kong, N. Wu, Ryan McBride, D. Sok, M. Pauthner, C. Cottrell, Travis Nieusma, C. Blattner, J. Paulson, P. Klasse, I. Wilson, D. Burton, A. Ward   +17 more
semanticscholar   +1 more source

Clinical Significance of Copper Chaperone for Superoxide Dismutase in Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Targeting Cu transport proteins is an innovative therapeutic approach for combating cancer. However, the mechanisms underlying the malignant potential of Cu transport proteins remain largely unknown. To address this issue, we focused on the oncogenic potential of copper chaperones for superoxide dismutase (CCS) in colorectal cancer (
Nobuo Takiguchi, Mamoru Uemura, Mao Osaki, Chikako Kusunoki, Masakatsu Paku, Mitsunobu Takeda, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mitsuyoshi Tei, Yoshinori Kagawa, Hirofumi Yamamoto, Yuichiro Doki, Hidetoshi Eguchi   +15 more
wiley   +1 more source

Tunable CH/π Interactions within a Tryptophan Zipper Motif to Stabilize the Fold of Long β-Hairpin Peptides. [PDF]

ACS Chem Biol, 2023
Richaud AD, Mandal S, Das A, Roche SP.
europepmc   +1 more source

Interpretability and Representability of Commutative Algebra, Algebraic Topology, and Topological Spectral Theory for Real‐World Data

Advanced Intelligent Discovery, EarlyView.
This article investigates how persistent homology, persistent Laplacians, and persistent commutative algebra reveal complementary geometric, topological, and algebraic invariants or signatures of real‐world data. By analyzing shapes, synthetic complexes, fullerenes, and biomolecules, the article shows how these mathematical frameworks enhance ...
Yiming Ren, Guo‐Wei Wei
wiley   +1 more source

Human dUTP pyrophosphatase: uracil recognition by a β hairpin and active sites formed by three separate subunits [PDF]

, 1996
Clifford D. Mol, Jonathan M. Harris, Evan M. McIntosh, John A. Tainer   +3 more
openalex   +1 more source

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

Effects of chirality and side chain length in C_α,α-dialkylated residues on β-hairpin peptide folded structure and stability. [PDF]

Org Biomol Chem, 2023
Heath SL, Horne WS, Lengyel GA.
europepmc   +1 more source