Results 81 to 90 of about 1,516,213 (305)
Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor [PDF]
, 2015 This research was supported by the University of St Andrews and grants provided by the Medical Research Council.Background: Streptococcus pneumoniae Neuraminidase A (NanA) is a multi-domain protein anchored to the bacterial surface.
Connaris, Helen +3 more
core +1 more source
Sustained release of active chemotherapeutics from injectable-solid β-hairpin peptide hydrogel.
Biomaterials Science, 2016 MAX8 β-hairpin peptide hydrogel is a solid, preformed gel that can be syringe injected due to shear-thinning properties and can recover solid gel properties immediately after injection.
Jessie E. P. Sun +6 more
semanticscholar +1 more source
Advanced Science, EarlyView.A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu +7 more
wiley +1 more source
Cytotoxic Potential of the Novel Horseshoe Crab Peptide Polyphemusin III
Marine Drugs, 2018 Biological activity of the new antimicrobial peptide polyphemusin III from the horseshoe crab Limulus polyphemus was examined against bacterial strains and human cancer, transformed, and normal cell cultures.
Mariana B. Marggraf +7 more
doaj +1 more source
A set of conformationally well-defined L/D-peptide epitopes provides a serological bar code for autoantibody subtypes. [PDF]
PLoS ONE, 2018 Which conformational parameters lead to an antibody-affine peptide antigen? And in how many different conformations can we actually present the respective conformational epitope? To provide answers from a chemical point of view, we direct the bending and
Andreas Schrimpf +3 more
doaj +1 more source
Functional Importance of the Hydrophobic Residue 362 in Influenza A PB1 Subunit
Viruses, 2023 PB1, acting as the catalytic subunit of the influenza polymerase, has numerous sequentially and structurally conserved regions. It has been observed that the slight modification of residues in PB1 would greatly affect the polymerase activity and even ...
Johnson Jor-Shing Chan +3 more
doaj +1 more source
Hydrodynamic Interactions in Protein Folding
, 2008 We incorporate hydrodynamic interactions (HI) in a coarse-grained and structure-based model of proteins by employing the Rotne-Prager hydrodynamic tensor. We study several small proteins and demonstrate that HI facilitate folding.
Dhont J. K. G. +2 more
core +1 more source
Advanced Science, EarlyView.TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen +16 more
wiley +1 more source
eLife, 2014 A large group of bacterial virulence autotransporters including AIDA-I from diffusely adhering E. coli (DAEC) and TibA from enterotoxigenic E. coli (ETEC) require hyperglycosylation for functioning.
Qing Yao +10 more
doaj +1 more source
Markov modeling of peptide folding in the presence of protein crowders
, 2018 We use Markov state models (MSMs) to analyze the dynamics of a $\beta$-hairpin-forming peptide in Monte Carlo (MC) simulations with interacting protein crowders, for two different types of crowder proteins [bovine pancreatic trypsin inhibitor (BPTI) and ...
Irbäck, Anders +2 more
core +1 more source