Results 1 to 10 of about 22,726 (148)

Role of β-hydroxybutyrate, its polymer poly-β-hydroxybutyrate and inorganic polyphosphate in mammalian health and disease [PDF]

open access: yesFrontiers in Physiology, 2014
We provide a comprehensive review of the role of β-hydroxybutyrate (β-OHB), its linear polymer poly-β-hydroxybutyrate (PHB) and inorganic polyphosphate (polyP) in mammalian health and disease.
Elena N. Dedkova, Lothar A. Blatter
doaj   +3 more sources

Adaptation to glucose restriction and β-hydroxybutyrate supplementation is associated with metabolic flexibility in lung cancer cells [PDF]

open access: yesScientific Reports
Metabolic reprogramming in tumor cells involves alterations in enzymatic machinery and metabolic profile reflect adaptive changes in malignant phenotypes.
Farzad Izak Shirian   +8 more
doaj   +2 more sources

Function and treatment strategies of β-hydroxybutyrate in aging

open access: yesSmart Materials in Medicine, 2023
Metabolic intermediates serve as precursors for bioactive molecule synthesis, the energy source for life activities, and signals for environmental adaptation. Ketone bodies are important metabolic intermediates produced in the liver by the degradation of
Yang Xiang   +4 more
doaj   +1 more source

Poly-β-hydroxybutyric acid in staphylococci [PDF]

open access: yesFEMS Microbiology Letters, 1989
Poly-β-hydroxybutyric acid (PHB) was extracted from various species of staphylococci isolated from different sources. IR and UV spectrophotometry and NMR analysis revealed that the compound consisted only of the β-hydroxybutyrate. The PHB level in the richest strain among investigated staphylococci is about 64-fold less than in bacilli.
Eligia Szewczyk, Jerzy Mikucki
openaire   +1 more source

The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation

open access: yesJournal of Nanobiotechnology, 2022
Background Aseptic Loosening (AL) following periprosthetic osteolysis is the main long-term complication after total joint arthroplasty (TJA). However, there is rare effective treatment except for revision surgery, which is costly and painful to the ...
Yanglin Wu   +8 more
doaj   +1 more source

Discrepancy of Beta-Hydroxybutyrate Measurements between a Blood Meter and GC-MS Methods in Healthy Humans

open access: yesMuscles, 2023
Ketone salt (KS) supplementation induces temporary nutritional ketosis to achieve potential exercise performance and health benefits. Racemic KS includes both D/L isomers of β-hydroxybutyrate, yet commercially available measurement devices (i.e., blood ...
Angelia Maleah Holland-Winkler   +4 more
doaj   +1 more source

Regulation of poly-β-hydroxybutyrate biosynthesis by nicotinamide nucleotide in Alcaligenes eutrophus [PDF]

open access: yesFEMS Microbiology Letters, 1995
Poly-β-hydroxybutyrate biosynthesis was studied in Alcaligenes eutrophus under various nutrient-limiting conditions. When the cells were cultivated in nitrogen-limited media, both the levels of NAD(P)H and the ratios of NAD(P)H/NAD(P) were higher than those under nitrogen-sufficient conditions.
In Young Lee   +3 more
openaire   +1 more source

Produced β-hydroxybutyrate after β-hydroxy-β-methylbutyrate (HMB) administration may contribute HMB function in mice

open access: yesBiochemistry and Biophysics Reports, 2021
β-Hydroxy-β-methylbutyrate (HMB) is an intermediate in the metabolism of the branched-chain amino acid leucine. HMB has several demonstrated effects on skeletal muscle function, some of which are contradictory.
Kazuki Ikeda   +9 more
doaj   +1 more source

Utilization of poly-β-hydroxybutyrate in free-living cultures ofRhizobiumORS571 [PDF]

open access: yesFEMS Microbiology Letters, 1986
The effect of carbon starvation on growth and poly-β-hydroxybutyrate (PHB) utilization in oxygen-limited chemostat cultures of Rhizobium ORS571 was studied. Under oxygen-limited growth conditions PHB was not degraded. When in a nitrogen-fixing oxygen-limited culture, after stopping the medium supply, the dissolved oxygen concentration was maintained at
Hein Stam   +3 more
openaire   +1 more source

Beta-hydroxybutyrate dampens adipose progenitors’ profibrotic activation through canonical Tgfβ signaling and non-canonical ZFP36-dependent mechanisms

open access: yesMolecular Metabolism, 2022
Background/Purpose: Adipose tissue contains progenitor cells that contribute to beneficial tissue expansion when needed by de novo adipocyte formation (classical white or beige fat cells with thermogenic potential).
Simon Lecoutre   +10 more
doaj   +1 more source

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