A single-institution retrospective analysis on the administration of β-lactam antibiotics prior to vancomycin in bacteremic patients. [PDF]
Cravero JC +5 more
europepmc +1 more source
Photodynamic inactivation (PDI) with methylene blue and 660 nm LED enhances antibiotic killing of bacteria, accelerating time‐kill kinetics and reducing the MDK99 compared to antibiotics alone. SEM confirms effective cellular damage, demonstrating that PDI potentiates amoxicillin and gentamicin against tolerant bacterial populations. ABSTRACT Bacterial
Bruna C. Correa +3 more
wiley +1 more source
Bacteriophage Therapy: Current Strategies and Future Perspectives
This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou +7 more
wiley +1 more source
Antimicrobial activity of β-lactam antibiotics against pneumococcal isolates causing pneumococcal disease in adults immediately before and after the COVID-19 pandemic in Spain (2019-2020). [PDF]
Llamosí M +10 more
europepmc +1 more source
The study reveals the inhibitory potential of encapsulated nanoparticles functionalized with moxifloxacin hydrochloride. ABSTRACT Bacterial resistance represents a significant global health threat associated with the development of microbial resistance genes.
Amanda S. Abreu +6 more
wiley +1 more source
Non-Membrane Active Peptide Resensitizes MRSA to β-Lactam Antibiotics and Inhibits S. aureus Virulence. [PDF]
Shi J +6 more
europepmc +1 more source
Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama +2 more
wiley +1 more source
A comprehensive review of cluster methods for drug–drug interaction network
Abstract The detection of drug–drug interaction (DDI) is crucial to the rational use of drug combinations. Experimentally, DDI detection is time‐consuming and laborious. Currently, researchers have developed a variety of computational methods to predict DDI.
Shuyuan Cao +3 more
wiley +1 more source
Phenyl urea based adjuvants for β-lactam antibiotics against methicillin resistant Staphylococcus aureus. [PDF]
Butman HS +9 more
europepmc +1 more source
High rates of multidrug resistance (MDR) and resistance genes against critical antibiotics, particularly quinolones and macrolides, were detected in poultry isolates. This finding poses a significant human health risk via the food chain and underscores the urgency of enhanced biosecurity measures.
Muazzez Yeşilyurt +2 more
wiley +1 more source

