Results 201 to 210 of about 61,324 (269)

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, Volume 13, Issue 35, 24 June 2026.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

A single-institution retrospective analysis on the administration of β-lactam antibiotics prior to vancomycin in bacteremic patients. [PDF]

Proc (Bayl Univ Med Cent)
Cravero JC, Telchik C, Yakubik T, Woods L, Park S, Sisco L.   +5 more
europepmc   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

Non-Membrane Active Peptide Resensitizes MRSA to β-Lactam Antibiotics and Inhibits S. aureus Virulence. [PDF]

Adv Sci (Weinh)
Shi J, Chen C, Kong P, Yu F, Lv Q, Wang Z, Liu Y.   +6 more
europepmc   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1833-1844, June 2026.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Fecal Microbiota Transplantation From Patients With Social Anxiety Disorder Is Associated With General Anxiety‐Like Behavior and Gut Microbiota Alterations in Mice

Brain and Behavior, Volume 16, Issue 6, June 2026.
Fecal microbiota transplantation from patients with social anxiety disorder (SAD) into mice induces anxiety‐like behaviors, accompanied by gut microbiota alterations (increased Bacteroidota, decreased butyrate producers), downregulation of microbial metabolic pathways, and reduced plasma tryptophan, suggesting a causal role of gut dysbiosis in SAD ...
Yu‐Chao Feng, Xiao‐Xuan Liu, Huan Yu, Rui Liu, Ting‐Song Pang, Hua‐Ning Wang, Zheng‐Wu Peng   +6 more
wiley   +1 more source

Phenyl urea based adjuvants for β-lactam antibiotics against methicillin resistant Staphylococcus aureus. [PDF]

Bioorg Med Chem Lett
Butman HS, Stefaniak MA, Walsh DJ, Gondil VS, Young M, Crow AH, Nemeth AM, Melander RJ, Dunman PM, Melander C.   +9 more
europepmc   +1 more source

Meropenem‐Induced Possible Mixed Drug‐Induced Liver Injury With Cholestatic Evolution: A Case Report Evaluated Using the Updated RUCAM (2016)

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Drug‐induced liver injury (DILI) remains a diagnosis of exclusion and requires systematic causality assessment. Meropenem is generally considered hepatically safe; however, rare cases of idiosyncratic DILI have been reported. We describe a 33‐year‐old female who developed progressive elevation of liver tests following exposure to meropenem ...
Nidal Mutawodeh, Sarah Saife, Akram Shalaby, Kamaleldein Einar, Motasem Kamal, Malik Hijaz, Tariq Hamadneh   +6 more
wiley   +1 more source

Antimicrobial activity of β-lactam antibiotics against pneumococcal isolates causing pneumococcal disease in adults immediately before and after the COVID-19 pandemic in Spain (2019-2020). [PDF]

Front Pharmacol
Llamosí M, Pérez-García C, Úbeda A, Vidal-Alcántara EJ, Pareja-Cerbán I, Gómez-Rubio E, Coronel P, Sanz JC, Domenech M, Sempere J, Yuste J.   +10 more
europepmc   +1 more source

An Uncommon Case of Ecthyma Gangrenosum in a Three‐Year‐Old Immunocompetent Child

Clinical Case Reports, Volume 14, Issue 6, June 2026.
The necrotic lesions on day 10. ABSTRACT Ecthyma gangrenosum (EG) is a rare cutaneous finding of Pseudomonas aeruginosa sepsis, typically in immunocompromised patients. We present EG with septic shock in a previously healthy three‐year‐old child who presented with rapidly progressing necrotic eschars and severe neutropenia.
Shobha Maharjan, Nipun Shrestha, Dhruba Shrestha   +2 more
wiley   +1 more source