Results 191 to 200 of about 74,405 (237)

Non-Membrane Active Peptide Resensitizes MRSA to β-Lactam Antibiotics and Inhibits S. aureus Virulence. [PDF]

Adv Sci (Weinh)
Shi J, Chen C, Kong P, Yu F, Lv Q, Wang Z, Liu Y.   +6 more
europepmc   +1 more source

A Bifunctional Protease Cleaves the Leader Peptide in the Biosynthesis of Class I Microviridins

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Biochemical characterization of the peptidase candidate NosP reveals bifunctional endo‐ and aminopeptidase activity in the leader peptide removal of class I microviridins from Nostoc punctiforme. The discovery of the first leader‐processing peptidase from microviridin biosynthesis may pave the way for the efficient production and bioengineering of ...
Nico Brüssow, Stella Scholz, Antje Stindt, Vincent Wiebach, Tino Damaszek, Roderich D. Süssmuth, Elke Dittmann, Martin Baunach   +7 more
wiley   +1 more source

Metalloids: Semi as Metals yet Full of Antimicrobial Potential

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm, Muhammad Jawad Nasim, Claus Jacob   +2 more
wiley   +1 more source

Antimicrobial activity of β-lactam antibiotics against pneumococcal isolates causing pneumococcal disease in adults immediately before and after the COVID-19 pandemic in Spain (2019-2020). [PDF]

Front Pharmacol
Llamosí M, Pérez-García C, Úbeda A, Vidal-Alcántara EJ, Pareja-Cerbán I, Gómez-Rubio E, Coronel P, Sanz JC, Domenech M, Sempere J, Yuste J.   +10 more
europepmc   +1 more source

The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia, Michael Kapsalis, Michael Georgoulakis, Athanasios Panousis, Constantinos G. Neochoritis   +4 more
wiley   +1 more source

Phenyl urea based adjuvants for β-lactam antibiotics against methicillin resistant Staphylococcus aureus. [PDF]

Bioorg Med Chem Lett
Butman HS, Stefaniak MA, Walsh DJ, Gondil VS, Young M, Crow AH, Nemeth AM, Melander RJ, Dunman PM, Melander C.   +9 more
europepmc   +1 more source

The Combination of Phage Therapy and β-Lactam Antibiotics for the Effective Treatment of Enterococcus faecalis Infections. [PDF]

Int J Mol Sci
Moryl M, Szychowska P, Dziąg J, Różalski A, Torzewska A.   +4 more
europepmc   +1 more source

Collateral Sensitivity to β-Lactam Antibiotics in Evolved Apramycin-Resistant MRSA. [PDF]

Int J Mol Sci
Wu J, Wu S, Liu J, Li C, Zheng M, Li F, Zhang Y, Wu Y, Yu Y.   +8 more
europepmc   +1 more source

Microbiological Risks to Health Associated with the Release of Antibiotic-Resistant Bacteria and β-Lactam Antibiotics Through Hospital Wastewater. [PDF]

Pathogens
Nolasco-Rojas AE, Cruz-Del-Agua E, Cruz-Cruz C, Loyola-Cruz MÁ, Ayil-Gutiérrez BA, Tamayo-Ordóñez MC, Tamayo-Ordoñez YJ, Rojas-Bernabé A, Tamayo-Ordoñez FA, Durán-Manuel EM, Paredes-Mendoza M, Márquez-Valdelamar LM, Jiménez-Zamarripa CA, Ocharan-Hernández E, Zárate-Segura PB, García-Hernández O, Sosa-Hernández O, Vásquez-Jiménez E, Calzada-Mendoza CC, Bello-López JM.   +19 more
europepmc   +1 more source