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Escherichia coli β-Lactamases: What Really Matters

open access: yesFrontiers in Microbiology, 2016
Escherichia coli strains belonging to diverse pathotypes have increasingly been recognized as a major public health concern. The β-lactam antibiotics have been used successfully to treat infections caused by pathogenic E. coli.
Priyanka eBajaj   +2 more
doaj   +2 more sources

Phenotypic detection of Metallo- and AmpC β-lactamases producing strains of P. aeruginosa in the state of Himachal Pradesh (India) [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2015
Background: A prospective study was undertaken to detect metallo-β-lactamases (MBLs) and AmpC β-lactamases in Pseudomonas aeruginosa isolates recovered from patients at Indira Gandhi Medical College, Shimla (H.P).
Naveen Minhas, Prakash Chand Sharma
doaj  

MOESM2 of Molecular characterization of β-lactamase genes in clinical isolates of carbapenem-resistant Acinetobacter baumannii

open access: yes, 2017
Additional file 2: Table S2. Primer sequences used for A. baumannii in present study.
Raible, Kevin   +6 more
openaire   +1 more source

Penetration of β-lactamase inhibitors into the periplasm of Gram-negative bacteria [PDF]

open access: yesFEMS Microbiology Letters, 1999
The effectiveness of a beta-lactamase inhibitor/beta-lactam combination against Gram-negative pathogens depends on many interplaying factors, one of which is the penetration of the inhibitor across the outer membrane. In this work we have measured the relative penetrations of clavulanic acid, sulbactam, tazobactam and BRL 42715 into two strains of ...
Farmer TH, Degnan BA, Payne DJ
openaire   +3 more sources

Detection and molecular characterization of β-lactamase genes in clinical isolates of Gram-negative bacteria in Southern Ecuador

open access: yesBrazilian Journal of Infectious Diseases, 2016
This work performed a phenotypic and genotypic characterization of 79 clinical isolates of Enterobacteriaceae and Pseudomonadaceae collected in hospitals of Southern Ecuadorin 2013.
Diana Yessenia Calva Delgado   +4 more
doaj   +1 more source

Cefotaxime-hydrolysing activity of the β-lactamase ofKlebsiella oxytocaD488 could be related to a threonine residue at position 140 [PDF]

open access: yesFEMS Microbiology Letters, 1991
The chromosomally encoded β-lactamase of Klebsiella oxytoca D483 strain, active against all third-generation cephalosporins but ceftazidime, was purified to homogeneity. The pure protein was digested by trypsin, Staphylococcus aureus V8 protease or proteinase Asp-N.
Alain Reynaud   +3 more
openaire   +1 more source

Detection of inducible β-lactamase by an agar dilution technique [PDF]

open access: yesFEMS Microbiology Letters, 1985
An agar dilution technique for the detection of inducible β-lactamase-mediated resistance to the newer cephalosporins is described. Cefoxitin (16 μg/ml) was incorporated in agar plates together with cefamandole (8 μg/ml) or cefotaxime (8 μg/ml). The susceptibility of 35 strains of Enterobacter cloacae to these combinations was compared with their ...
openaire   +1 more source

Construction by polymerase chain reaction and intragenic DNA probes for three main types of transferable β-lactamases (TEM, SHV, CARB) [PDF]

open access: yesFEMS Microbiology Letters, 1991
Intragenic DNA probes were synthesized by polymerase chain reaction using fragments of the genes of three major types of β-lactamases (TEM, SHV, CARB) as templates. The TEM probe hybridized with the genes encoding TEM-1, TEM-2 and six extended-spectrum related enzymes (TEM-3 to TEM-7, TEM-20) in colony hybridizations and Southern-blot analysis. The SHV
G. Arlet, A. Philippon
openaire   +1 more source

Detection of metallo-β-lactamase gene blaIMP of Escherichia coli clinical isolates in Sanglah General Hospital Bali

open access: yesIndonesia Journal of Biomedical Science, 2019
Background: Escherichia coli belong to the family of Enterobacteriaceae that are responsible as one of the leading cause of nosocomial infections. The emergence of Carbapenem-resistant Enterobacteriaceae presents therapeutic challenges for clinicians on choosing the correct type of antibiotics to prescribe.
Muhammad Ardi Afriansyah   +2 more
openaire   +1 more source

MOESM1 of Efficient production of secretory Streptomyces clavuligerus β-lactamase inhibitory protein (BLIP) in Pichia pastoris

open access: yes, 2018
Additional file 1.
Law, Kin-Ho   +7 more
openaire   +1 more source

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