Results 21 to 30 of about 729,044 (285)
TEM-E1: a novel β-lactamase conferring resistance to ceftazidime [PDF]
FEMS Microbiology Letters, 1989 A novel β-lactamase, conferring resistance to ceftazidime, has been identified to be encoded by a 31 kb plasmid (pUK720) in a clinical E. coli strain isolated in Belgium. The β-lactamase, new designated TEM-E1, has a pI of approximately 5.4 and lies in between the iso-electric focused bands of the β-lactamases TEM-1 and TEM-7.
D.J. Payne, M.S. Marriott, S.G.B. Amyes
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Evolution of β-lactamases and enzyme promiscuity [PDF]
, 2021 This is a pre-copyedited, author-produced version of an article accepted for publication in Protein Engineering Design & Selection following peer review. The version of record Fröhlich, C.F., Chen, J.Z., Gholipour, S., Erdogan, A.N. & Tokuriki, N. (2021).
Chen, John Z +5 more
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Genetics of Acquired Antibiotic Resistance Genes in Proteus spp.
Frontiers in Microbiology, 2020 Proteus spp. are commensal Enterobacterales of the human digestive tract. At the same time, P. mirabilis is commonly involved in urinary tract infections (UTI). P.
Delphine Girlich +11 more
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Identification and characterization of a novel β-lactamase TLE-2, encoded by plasmid pUK702 [PDF]
FEMS Microbiology Letters, 1987 A novel plasmid-mediated β-lactamase has been identified in a Klebsiella pneumoniae strain, carried by a plasmid pUK702. The pUK702 plasmid encodes TEM-1 and SHV-1 β-lactamase enzymes in addition to the novel enzyme. The novel enzyme has an Mr of 19 000 and a pI of 6.5. The enzyme is TEM-like in substrate profile and has been designated TLE-2 (TEM-like
Alison J. Reid +3 more
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Scientific Reports, 2021 New Delhi metallo-β-lactamase variants and different types of metallo-β-lactamases have attracted enormous consideration for hydrolyzing almost all β-lactam antibiotics, which leads to multi drug resistance bacteria.
Azhar Salari-jazi +4 more
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Virulence of non-β-lactamase-mediated ampicilin-resistantHaemophilus influenzae [PDF]
FEMS Microbiology Letters, 1991 We questioned whether strains of ampicillin-resistant, non-β-lactamase-producing (AmpR NBLP) Haemophilus influenae with lower affinity penicillin-binding proteins (PBPs) might have altered virulence. The virulence of resistant transformant strains and the susceptible recipient was compared using infant rats. Following intraperitoneal inoculation, there
Lorry G. Rubin +3 more
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LXA-1: a new plasmid-mediated β-lactamase giving low-level resistance [PDF]
FEMS Microbiology Letters, 1988 LXA-1, a novel plasmid-mediated β-lactamase, was observed in clinical isolates of Klebsiella oxytoca, Klebsiella pneumoniae, Citrobacter freundii and Enterobacter cloacae. All the strains additionally produced TEM-1 β-lactamase. LXA-1 had an Mr of 24 000 and a pI of 6.7.
Youjun Yang, G.A. Jacoby, D.M. Livermore
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Investigation of beta-lactase enzymes in chromosomal bacilli isolated from diarrhea in children [PDF]
مجلة التربية والعلم, 2008 Thirty clinical isolates of gram negative bacilli isolated from diarrhea cases in children aged ≤5 years were investigated for the presence of β-lactamases, and it was found that 21 (70%) of them contain these enzymes.
Shaker Jarjees, Mahmoud Alleh
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Resistance of Some Bacteria Isolated from Urinary Tract Infections in Elderly Patients to Antibiotics and Detection of β-lactamases in Them [PDF]
مجلة التربية والعلم, 2021 Urinary tract infection is the second-largest infection, especially in elderly people, and the increasing use of antibiotics has led to the emergence and development of resistance in isolated and other bacteria in this study Fifty urine samples from ...
Mohammed Mahmood +2 more
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The Mechanisms of Catalysis by Metallo β-Lactamases [PDF]
, 2008 Class B β-lactamases or metallo-β-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of β-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins.
Michael I. Page +3 more
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