Results 11 to 20 of about 28,374 (228)

Virulence of non-β-lactamase-mediated ampicilin-resistantHaemophilus influenzae [PDF]

open access: yesFEMS Microbiology Letters, 1991
We questioned whether strains of ampicillin-resistant, non-β-lactamase-producing (AmpR NBLP) Haemophilus influenae with lower affinity penicillin-binding proteins (PBPs) might have altered virulence. The virulence of resistant transformant strains and the susceptible recipient was compared using infant rats. Following intraperitoneal inoculation, there
Lorry G. Rubin   +3 more
openaire   +1 more source

LXA-1: a new plasmid-mediated β-lactamase giving low-level resistance [PDF]

open access: yesFEMS Microbiology Letters, 1988
LXA-1, a novel plasmid-mediated β-lactamase, was observed in clinical isolates of Klebsiella oxytoca, Klebsiella pneumoniae, Citrobacter freundii and Enterobacter cloacae. All the strains additionally produced TEM-1 β-lactamase. LXA-1 had an Mr of 24 000 and a pI of 6.7.
Youjun Yang, G.A. Jacoby, D.M. Livermore
openaire   +1 more source

Investigation of beta-lactase enzymes in chromosomal bacilli isolated from diarrhea in children [PDF]

open access: yesمجلة التربية والعلم, 2008
Thirty clinical isolates of gram negative bacilli isolated from diarrhea cases in children aged ≤5 years were investigated for the presence of β-lactamases, and it was found that 21 (70%) of them contain these enzymes.
Shaker Jarjees, Mahmoud Alleh
doaj   +1 more source

Molecular Characterization of AmpC β-lactamases in Enterobacteriaceae

open access: yesJournal of Pure and Applied Microbiology, 2022
AmpC β-lactamases are enzymes that are resistant to β-lactams, such as penicillin and cephalosporin, but not cefoxitin and cefotetan. This study was conducted to characterize AmpC β-lactamases in Enterobacteriaceae.
D. Bindu, Chitralekha Saikumar
doaj   +1 more source

Resistance of Some Bacteria Isolated from Urinary Tract Infections in Elderly Patients to Antibiotics and Detection of β-lactamases in Them [PDF]

open access: yesمجلة التربية والعلم, 2021
Urinary tract infection is the second-largest infection, especially in elderly people, and the increasing use of antibiotics has led to the emergence and development of resistance in isolated and other bacteria in this study Fifty urine samples from ...
Mohammed Mahmood   +2 more
doaj   +1 more source

Higher Prevalence of PldA, a Pseudomonas aeruginosa Trans-Kingdom H2-Type VI Secretion System Effector, in Clinical Isolates Responsible for Acute Infections and in Multidrug Resistant Strains

open access: yesFrontiers in Microbiology, 2018
Pseudomonas aeruginosa can manipulate eukaryotic host cells using secreted effectors delivered by the type III or the type VI Secretion Systems (T3SS and T6SS). The T3SS allows the injection of bacterial effectors (Exo toxins) into eukaryotic cell.
Thibaud Boulant   +10 more
doaj   +1 more source

Transcriptional Landscape of a blaKPC-2 Plasmid and Response to Imipenem Exposure in Escherichia coli TOP10

open access: yesFrontiers in Microbiology, 2018
The diffusion of KPC-2 carbapenemase is closely related to the spread of Klebsiella pneumoniae of the clonal-group 258 and linked to IncFIIK plasmids. Little is known about the biology of multi-drug resistant plasmids and the reasons of their successful ...
Agnès B. Jousset   +16 more
doaj   +1 more source

Phenotypic and Molecular Detection of Extended Spectrum Beta-Lactamases Producing-Bacteria Isolated From Pregnant Women With Genital Tract Infection in Duhok Governorate

open access: yesScience Journal of University of Zakho, 2021
Beta-lactamase producing bacteria have a worldwide distribution with a high degree of prevalence in both community and hospital. Furthermore, multidrug resistant (MDR) and extended spectrum β-lactamases (ESBL) producing bacterial isolates from women ...
Sozan M. Nerway, Muna S. Al-Delaimi
doaj   +1 more source

Metallo-β-Lactamases and Aptamer-Based Inhibition

open access: yesPharmaceuticals, 2011
An evolution of antibiotic-resistant bacteria has resulted in the need for new antibiotics. β-Lactam based drugs are the most predominantly prescribed antibiotics to combat bacterial infections; however, production of β-lactamases, which catalyze the ...
Sung-Kun Kim   +3 more
doaj   +1 more source

Mutation of serine residue 318 in the class C β-lactamase ofEnterobacter cloacae908R [PDF]

open access: yesFEMS Microbiology Letters, 1992
The involvement of the serine residue 318 in the specificity of a class C β-lactamase was investigated. Multiple site-directed mutants at this position were generated using a polymerase chain reaction technique. These mutants were then probed for their activity towards various β-lactam compounds.
Christine Jacobs   +4 more
openaire   +1 more source

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