Results 11 to 20 of about 729,044 (285)
Molecular Characterization of AmpC β-lactamases in Enterobacteriaceae
Journal of Pure and Applied Microbiology, 2022 AmpC β-lactamases are enzymes that are resistant to β-lactams, such as penicillin and cephalosporin, but not cefoxitin and cefotetan. This study was conducted to characterize AmpC β-lactamases in Enterobacteriaceae.
D. Bindu, Chitralekha Saikumar
doaj +3 more sources
Antibiotics, 2014 The Class D β-lactamases have emerged as a prominent resistance mechanism against β-lactam antibiotics that previously had efficacy against infections caused by pathogenic bacteria, especially by Acinetobacter baumannii and the Enterobacteriaceae.
Nuno T. Antunes, Jed F. Fisher
doaj +2 more sources
Metallo-β-Lactamases and Aptamer-Based Inhibition
Pharmaceuticals, 2011 An evolution of antibiotic-resistant bacteria has resulted in the need for new antibiotics. β-Lactam based drugs are the most predominantly prescribed antibiotics to combat bacterial infections; however, production of β-lactamases, which catalyze the ...
Sung-Kun Kim +3 more
doaj +2 more sources
Novel monoclonal antibodies for immunodetection of AmpC β-lactamases [PDF]
PeerJBackground Accurate and easy-to-perform assays for the detection of antibiotic-resistant bacterial isolates producing AmpC β-lactamases are epidemiologically relevant, leading to more effective use of antibiotics and a comprehensive understanding of β ...
Karolina Bielskė +6 more
doaj +3 more sources
Cooperative resistance varies among β-lactamases in E. coli, with some enabling cross-protection and sustained extracellular activity [PDF]
Communications Biologyβ-lactamases confer bacteria resistance to β-lactam antibiotics, and interestingly, this protective effect can extend to neighboring susceptible cells. However, knowledge of this cooperative resistance remains limited.
Qinqin Wang +2 more
doaj +2 more sources
Characterization of acquired β-lactamases in Pseudomonas aeruginosa and quantification of their contributions to resistance [PDF]
Microbiology SpectrumPseudomonas aeruginosa is a highly problematic opportunistic pathogen that causes a range of different infections. Infections are commonly treated with β-lactam antibiotics, including cephalosporins, monobactams, penicillins, and carbapenems, with ...
Karl A. Glen, Iain L. Lamont
doaj +2 more sources
OXA β-lactamases from Acinetobacter spp. are membrane bound and secreted into outer membrane vesicles [PDF]
mBioβ-lactamases from Gram-negative bacteria are generally regarded as soluble, periplasmic enzymes. NDMs have been exceptionally characterized as lipoproteins anchored to the outer membrane. A bioinformatics study on all sequenced β-lactamases was performed
Lucia Capodimonte +6 more
doaj +2 more sources
RUHS Journal of Health Sciences, 2023 Introduction: Infections are the major cause of morbidity and mortality in burn patients. The ESBL, MBL and AmpC are the major mediators of antimicrobial resistance in gram negative bacteria. Early detection of ESBL, MBL and AmpC β -lactamases is crucial
Kusum Lata Lodha, Seema Surana
doaj +1 more source
Drug development concerning metallo-β-lactamases in gram-negative bacteria
Frontiers in Microbiology, 2022 β-Lactams have been a clinical focus since their emergence and indeed act as a powerful tool to combat severe bacterial infections, but their effectiveness is threatened by drug resistance in bacteria, primarily by the production of serine- and metallo-β-
Xiuyun Li +7 more
doaj +1 more source
A β-lactamase produced by a thermophilicBacillus [PDF]
FEMS Microbiology Letters, 1996 A β-lactamase was purified from a thermophilic Bacillus strain, that had been isolated from a traditional hot bath in the Meknes area (Morocco). The properties of the enzyme were very similar to those of the β-lactamase produced by Bacillus licheniformis 749C but it exhibited a somewhat increased thermostability and a higher activation energy with ...
Fouzia Rhazi-Filali +5 more
openaire +1 more source