Molecular Characterization of AmpC β-lactamases in Enterobacteriaceae [PDF]
Journal of Pure and Applied Microbiology, 2022 AmpC β-lactamases are enzymes that are resistant to β-lactams, such as penicillin and cephalosporin, but not cefoxitin and cefotetan. This study was conducted to characterize AmpC β-lactamases in Enterobacteriaceae.
D. Bindu, Chitralekha Saikumar
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Metallo-β-Lactamases and Aptamer-Based Inhibition
Pharmaceuticals, 2011 An evolution of antibiotic-resistant bacteria has resulted in the need for new antibiotics. β-Lactam based drugs are the most predominantly prescribed antibiotics to combat bacterial infections; however, production of β-lactamases, which catalyze the ...
Sung-Kun Kim +3 more
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Antibiotics, 2014 The Class D β-lactamases have emerged as a prominent resistance mechanism against β-lactam antibiotics that previously had efficacy against infections caused by pathogenic bacteria, especially by Acinetobacter baumannii and the Enterobacteriaceae.
Nuno T. Antunes, Jed F. Fisher
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Novel monoclonal antibodies for immunodetection of AmpC β-lactamases [PDF]
PeerJBackground Accurate and easy-to-perform assays for the detection of antibiotic-resistant bacterial isolates producing AmpC β-lactamases are epidemiologically relevant, leading to more effective use of antibiotics and a comprehensive understanding of β ...
Karolina Bielskė +6 more
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, 2014 The OXA β-lactamases were among the earliest β-lactamases detected; however, these molecular class D β-lactamases were originally relatively rare and always plasmid mediated.
Benjamin A. Evans (3115968) +1 more
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Cooperative resistance varies among β-lactamases in E. coli, with some enabling cross-protection and sustained extracellular activity [PDF]
Communications Biologyβ-lactamases confer bacteria resistance to β-lactam antibiotics, and interestingly, this protective effect can extend to neighboring susceptible cells. However, knowledge of this cooperative resistance remains limited.
Qinqin Wang +2 more
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Antifungal agent tavaborole as a potential broad-spectrum serine and metallo-β-lactamases inhibitorResearch in context [PDF]
EBioMedicineSummary: Background: The global emergence and spread of carbapenem-resistant Enterobacteriaceae in clinical settings have driven the search for inhibitors that can counteract carbapenemases.
Yan Zhang +15 more
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Evolution of β-lactamases and enzyme promiscuity [PDF]
, 2021 This is a pre-copyedited, author-produced version of an article accepted for publication in Protein Engineering Design & Selection following peer review. The version of record Fröhlich, C.F., Chen, J.Z., Gholipour, S., Erdogan, A.N. & Tokuriki, N. (2021).
Chen, John Z +5 more
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Investigation of beta-lactase enzymes in chromosomal bacilli isolated from diarrhea in children [PDF]
مجلة التربية والعلم, 2008 Thirty clinical isolates of gram negative bacilli isolated from diarrhea cases in children aged ≤5 years were investigated for the presence of β-lactamases, and it was found that 21 (70%) of them contain these enzymes.
Shaker Jarjees, Mahmoud Alleh
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Resistance of Some Bacteria Isolated from Urinary Tract Infections in Elderly Patients to Antibiotics and Detection of β-lactamases in Them [PDF]
مجلة التربية والعلم, 2021 Urinary tract infection is the second-largest infection, especially in elderly people, and the increasing use of antibiotics has led to the emergence and development of resistance in isolated and other bacteria in this study Fifty urine samples from ...
Mohammed Mahmood +2 more
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