Results 211 to 220 of about 1,672,197 (320)

Gel electrofocusing combined with zymogram techniques for the characterization of β-lactamases from gram negative bacteria [PDF]

FEMS Microbiology Letters, 1977
B. Olsson, C.-E. Nord, T. Wadström, B. Wretlind   +3 more
openaire   +1 more source

MOESM1 of Single nucleotide polymorphisms in genes encoding penicillin-binding proteins in β-lactamase-negative ampicillin-resistant Haemophilus influenzae in Japan

, 2018
Additional file 1. Reference sequences used in this study.
Misawa, Kazuhisa, Tarumoto, Norihito, Tamura, Shinsuke, Morichika Osa, Hamamoto, Takaaki, Yuki, Atsushi, Kouzaki, Yuji, Imai, Kazuo, Runtuwene Ronald, Yamaguchi, Toshiyuki, Murakami, Takashi, Shigefumi Maesaki, Suzuki, Yutaka, Kawana, Akihiko, Maeda, Takuya   +14 more
openaire   +1 more source

NCY‐1 β‐Lactamase Activity Correlates With Antimicrobial Susceptibility of a Clinical Strain of Nocardia cyriacigeorgica

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
This study shows a strong correlation between the β‐lactam susceptibility profile of a clinical isolate of Nocardia cyriacigeorgica and the activity of its β‐lactamase, NCY‐1. Inhibitors of NCY‐1 reduce the minimum inhibitory concentration of amoxicillin.
Julie Couston, Athénaïs Le Marchand, Elisabeth Hodille, Charlotte Genestet, Brune Joannard, Jérôme Feuillard, Yvonne Benito, Oana Dumitrescu, Mickaël Blaise   +8 more
wiley   +1 more source

Presence of extended spectrum β-lactamase producing Escherichia coli in wild geese [PDF]

, 2011
Butaye, Patrick, Garmyn, An, Haesebrouck, Freddy, Hellebuyck, Tom, Martel, An, Pasmans, Frank, Smet, Annemieke   +6 more
core   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source

Heterogeneous hydrolytic features for OXA-48-like β-lactamases [PDF]

, 2015
Objectives: Carbapenem-hydrolysing class D β-lactamases of the OXA-48 type are increasingly reported from Enterobacteriaceae. β-Lactamase OXA-48 hydrolyses penicillins very efficiently, but carbapenems only weakly and spares broad-spectrum ...
Nordmann, Patrice, Oueslati, Saoussen, Poirel, Laurent   +2 more
core  

SegDesign: A modular framework for controllable protein segment engineering

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Local protein structure engineering, such as targeted remodeling of loops or flexible regions, is critical for mechanistic studies and protein optimization but remains challenging to perform in a controllable and reproducible manner. Despite advances in protein foundation models and generative structure design, most existing methods emphasize ...
Chenjie Feng, Junbo Yin, Chao Zha, Mohammed Saif, Xiaopeng Xu, Xin Gao, Wenjia He   +6 more
wiley   +1 more source

Enhancing diabetic foot osteomyelitis diagnosis with metagenomics next‐generation sequencing, proof of concept

Diabetic Medicine, Volume 43, Issue 4, April 2026.
The use of mNGS with the MinION tool clearly provides a significant advantage compared to routine culture by identifying a higher diversity of pathogens in diabetic foot osteomyelitis. It also highlights the value of this method in clinical decision making, despite the technical challenges inherent in metagenomic sequencing.
Madjid Morsli, Chloé Magnan, Florian Salipante, Adeline Dubois, Sophie Schuldiner, Nicolas Cellier, Albert Sotto, Jean‐Philippe Lavigne, Catherine Dunyach‐Remy   +8 more
wiley   +1 more source

The depletion of serine beta‐lactamase‐like protein (LACTB) ameliorates metabolic dysfunction–associated steatotic liver disease by reducing ubiquitin‐mediated degradation of carnitine palmitoyltransferase 2

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2962-2977, April 2026.
Abstract Aims Metabolic dysfunction–associated steatotic liver disease (MASLD) represents one of the most common chronic liver disorders worldwide, and its incidence continues to rise each year. Serine β‐lactamase‐like protein (LACTB) is a serine protease that plays a crucial role in lipid metabolism and hepatocellular carcinoma, but its function in ...
Wujiang Shi, Xin Liu, Nan Wang, Qianwen Zhang, Jianjun Gao, Canghai Guan, Yapeng Li, Chengru Yang, Shaowu Bi, Xinlei Zou, Xiangyu Zhong   +10 more
wiley   +1 more source

Metallo-β-Lactamases: the Quiet before the Storm?

Clinical Microbiology Reviews, 2005
T. Walsh, M. Toleman, L. Poirel, P. Nordmann   +3 more
semanticscholar   +1 more source