Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh +11 more
wiley +1 more source
Contribution of mutational resistance mechanisms and acquired β-lactamases to cefiderocol/xeruborbactam susceptibility in Pseudomonas aeruginosa. [PDF]
González-Pinto L +10 more
europepmc +1 more source
Multidrug‐Resistant Pathogen Clonal Spread in Nigeria: A Systematic Review and Meta‐Analysis
ABSTRACT Background and Aim The rapid dissemination of multidrug‐resistant (MDR) bacterial clones poses a global health threat and limits treatment options. Understanding the dynamics of bacterial clones in Nigeria is essential for developing effective control strategies. This systematic review aimed to track MDR pathogen clones in Nigeria. Methods The
Emmanuel N. Ugbo +5 more
wiley +1 more source
Foodborne antibiotics enrich human gut microbiota with pathogens producing extended-spectrum β-lactamases and carbapenemases. [PDF]
Martak D +7 more
europepmc +1 more source
ABSTRACT Background and Aims Urinary tract infections (UTIs) are prevalent among adolescent girls. Therefore, effective promotional campaigns are crucial for conveying accurate information. This study aimed to assess the prevalence and the antimicrobial profiling of the isolated uropathogens among 354 adolescent girls. Methods This is a cross‐sectional
Shimaa Abdelrahim Khalaf +5 more
wiley +1 more source
Distribution and Evolutionary Trajectories of β-Lactamases in Vibrio: Genomic Insights from Carbenicillin-Hydrolyzing Class A β-Lactamases (CARB) in the Harveyi and Cholerae Clades. [PDF]
Yang Y, Jin X, Zhao Z.
europepmc +1 more source
Characterisation of a novel plasmid-mediated β-lactamase and its contribution to β-lactam resistance inPseudomonas aeruginosa [PDF]
I.N. Simpson +5 more
openaire +1 more source
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo +9 more
wiley +1 more source
Contrasting pH optima of β-lactamases CTX-M and CMY influence <i>Escherichia coli</i> fitness and resistance ecology. [PDF]
Anbo M +7 more
europepmc +1 more source
Resistome flow in global landfill systems
Global landfill systems represent key hubs of resistome, serving as dynamic reservoirs and amplifiers through plasmid‐driven gene mobility. Waste flows and environmental pathways sustain the transboundary resistome networks, accelerating resistance dissemination across ecosystems.
Wenqing Hong +12 more
wiley +1 more source

