Results 251 to 260 of about 1,672,197 (320)

Proposal of metagenomic-origin LRA-5 as a precursor of active β-lactamases through Tyr69Gln and Val166Glu amino acid substitutions: a functional and structural analysis. [PDF]

Antimicrob Agents Chemother
D'Amico González G, Rodríguez MM, Penzotti P, Brunetti F, Ghiglione B, Moe LA, Centrón D, Gutkind G, Gao L, Haider S, Powers RA, Klinke S, Power P.   +12 more
europepmc   +1 more source

β-Lactamases: A Focus on Current Challenges.

Cold Spring Harbor Perspectives in Medicine, 2017
R. Bonomo
semanticscholar   +1 more source

NMR Characterization of the Influence of Zinc(II) Ions on the Structural and Dynamic Behavior of the New Delhi Metallo-β-Lactamase‑1 and on the Binding with Flavonols as Inhibitors

ACS Omega, 2020
Gwladys Rivière, Saoussen Oueslati, Maud Gayral, Jean-Bernard Créchet, Naïma Nhiri, Eric Jacquet, Jean-Christophe Cintrat, François Giraud, Carine van Heijenoort, Ewen Lescop, Stéphanie Pethe, Bogdan I. Iorga, Thierry Naas, Eric Guittet, Nelly Morellet   +14 more
doaj   +1 more source

Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like β-lactamases. [PDF]

RSC Med Chem
Hoff JF, Goudar KE, Calvopiña K, Beer M, Hinchliffe P, Shaw JM, Tooke CL, Takebayashi Y, Cadzow AF, Harmer NJ, Mulholland AJ, Schofield CJ, Spencer J.   +12 more
europepmc   +1 more source

Evaluation of the Potential Carrier and Controlled Release of Antibiotics by Zinc, Nickel, and Cobalt Ferrite Nanoparticles Encapsulated with Silica and Functionalized with Moxifloxacin Hydrochloride

Particle &Particle Systems Characterization, Volume 43, Issue 3, March 2026.
The study reveals the inhibitory potential of encapsulated nanoparticles functionalized with moxifloxacin hydrochloride. ABSTRACT Bacterial resistance represents a significant global health threat associated with the development of microbial resistance genes.
Amanda S. Abreu, Stéfanne R. R. Ferreira, Naiara G. Cabral, Romayne P. França, Hanstter H. A. Rezende, Richard Landers, Alexandre Pancotti   +6 more
wiley   +1 more source

Urban wastewater overflows as hotspots for dissemination of bacteria producing extended-spectrum β-lactamases and carbapenemases in the Suquía River, Argentina. [PDF]

Front Microbiol
Ruiz SE, Morandini FN, Panzetta ME, Lipari FG, Irrazábal MG, Toselli R, Der Ohannesian M, Amieva C, Valdes ME, Giraudo FJ, Rollán MDR, Amé V, Sola C, Saka HA.   +13 more
europepmc   +1 more source

Bismuth Bicycles

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
Discovery, evolution and potential future applications of bismuth bicycle molecules—a novel class of therapeutics with unique properties. ABSTRACT Bicyclic peptides are emerging as next generation therapeutics by combining the affinity and specificity of antibodies with the synthetic convenience of small molecules.
Saan Voss, Amin Sagar, Arnaud Tiberghien, Richard J. L. Hughes, Liuhong Chen, Inmaculada Rioja, Mark Frigerio, Michael J. Skynner, David R. Spring   +8 more
wiley   +1 more source

A β-lactamase inhibitory protein mutant displays high potency and a broad inhibition profile due to an altered binding mode with β-lactamases. [PDF]

J Biol Chem
Rivera P, Lu S, Ngango D, Sankaran B, Venkataram Prasad B, Palzkill T.   +5 more
europepmc   +1 more source

Loop‐Mediated Isothermal Amplification (LAMP) Assay for the Detection of Bacterial Bovine Mastitis: A Systematic Review

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Loop‐mediated isothermal amplification (LAMP) is a quick, cost‐effective molecular technique for detecting bacterial pathogens causing bovine mastitis. This review summarises 18 LAMP assays developed for key bacteria such as Staphylococcus aureus, Streptococcus agalactiae, Streptococcus uberis and Escherichia coli.
Tewodros Fentahun Jember, Mark E. Westman, Sameer Dinkar Pant, Seyed Ali Ghorashi   +3 more
wiley   +1 more source

A glycine at position 105 leads to clavulanic acid and avibactam resistance in class A β-lactamases. [PDF]

J Biol Chem
Radojković M, Chikunova A, Koene SF, Timmer M, Natarajan SV, Boyle AL, Ubbink M.   +6 more
europepmc   +1 more source