Results 181 to 190 of about 1,666,677 (276)

Combinations comprising dual β-lactams and a β-lactamase inhibitor achieve optimal synergistic inhibition of <i>Mycobacterium abscessus</i> growth. [PDF]

Antimicrob Agents Chemother
Rimal B, Xie Y, Panthi CM, Devlin KL, Beatty KE, Lamichhane G.   +5 more
europepmc   +1 more source

One ring to rule them all: Current trends in combating bacterial resistance to the β‐lactams

Protein Science, 2016
D. King, S. Sobhanifar, N. Strynadka
semanticscholar   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source

Adjunctive β-lactams for <i>Staphylococcus aureus</i> bacteremia: a narrative review. [PDF]

Ther Adv Infect Dis
Chastain DB, White BP, Henao-Martínez AF, Tu PJ, Bland CM, Foster RA, Cluck DB.   +6 more
europepmc   +1 more source

The synthesis of some β-lactams and investigation of their metal-chelating activity, carbonic anhydrase and acetylcholinesterase inhibition profiles

Journal of Enzyme Inhibition and Medicinal Chemistry, 2016
Burhanettin Turan, K. Şendil, E. Şengül, M. Gültekin, Parham Taslimi, I. Gulcin, C. Supuran   +6 more
semanticscholar   +1 more source

A Machine Learning‐Based Model for Individualized Prediction of Vancomycin Concentration‐Time Curves in ICU Patients

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
A machine learning–integrated pharmacokinetic model improves individualized prediction of vancomycin concentration–time profiles in ICU patients and outperforms traditional pharmacokinetic models, providing a practical decision‐support tool for precision dosing.
Jing‐Yi Wang, Jiang Hu, Yan Chen, Shan Li, Jin‐Min Peng, Run Dong, Xiao‐Yun Hu, Wei Jiang, Chun‐Yao Wang, Li Weng, Bin Du, the China Critical Care Clinical Trials Group (CCCCTG)   +11 more
wiley   +1 more source

Photoinduced carbonylative annulation access to β-lactams. [PDF]

Chem Sci
Wang Y, Qi X, Bao ZP, Wu XF.
europepmc   +1 more source

Emergence of Tigecycline‐Resistant Pseudomonas aeruginosa Harbouring tmexC6D6‐toprJ1b From Hospital Sewage in Japan

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
This study isolated a Pseudomonas aeruginosa strain (KAM950) carrying the tmexCD‐toprJ gene cluster from hospital sewage in Japan. The strain exhibited reduced susceptibility to tigecycline and carbapenems, harboured chromosomal tmexC6D6‐toprJ1b and oprD disruption, and belonged to epidemic clone ST244, emphasising emerging multidrug resistance and the
Shotaro Maehana, Masato Suzuki, Naoko Ishimura, Hiroki Izawa, Ryotaro Eda, Masaki Nakamura, Mohan Amarasiri, Takashi Furukawa, Fumiaki Kojima, Kazunari Sei, Makoto Kubo   +10 more
wiley   +1 more source

Anti-microbial resistance to β-lactams and prevalence of colicin genes among phylotypes of <i>Escherichia coli</i> isolates from hedgehogs. [PDF]

Vet Res Forum
Jajarmi M, Sahraei S, Mohseni P, Hajipour P, Reshadi P, Heydari F, Akhtardanesh B, Ghanbarpour N, Rashidi M, Adib N, Abiri Z, Amirinezhad H.   +11 more
europepmc   +1 more source

Enhancing diabetic foot osteomyelitis diagnosis with metagenomics next‐generation sequencing, proof of concept

Diabetic Medicine, Volume 43, Issue 4, April 2026.
The use of mNGS with the MinION tool clearly provides a significant advantage compared to routine culture by identifying a higher diversity of pathogens in diabetic foot osteomyelitis. It also highlights the value of this method in clinical decision making, despite the technical challenges inherent in metagenomic sequencing.
Madjid Morsli, Chloé Magnan, Florian Salipante, Adeline Dubois, Sophie Schuldiner, Nicolas Cellier, Albert Sotto, Jean‐Philippe Lavigne, Catherine Dunyach‐Remy   +8 more
wiley   +1 more source