Results 201 to 210 of about 36,552 (249)

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, Volume 13, Issue 44, 7 August 2026.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

The antimycotic 5-fluorocytosine is a virulence inhibitor of uropathogenic <i>Escherichia coli</i> and eradicates biofilm-embedded bacteria synergizing with β-lactams. [PDF]

Antimicrob Agents Chemother
Ravishankar S, Conte AL, Carrasco Aliaga SJ, Baldelli V, Nielsen KL, Paroni M, Conte MP, Landini P, Rossi E.   +8 more
europepmc   +1 more source

The Development and Validation of a Simple Method for the Determination of Meropenem Concentrations in Human Plasma Using High‐Performance Liquid Chromatography

Applied Research, Volume 5, Issue 4, August 2026.
A simple, rapid, and sustainable HPLC‐UV method was developed and validated to quantify meropenem in human plasma across a wide linear range (0.5–100 mg/L). Utilizing an efficient one‐step protein precipitation, this eco‐friendly approach is highly suited for routine clinical therapeutic drug monitoring and research purposes.
Asma Aboelezz, Maged Kharouba, Sherif Hanafy Mahmoud   +2 more
wiley   +1 more source

Development and <i>in vitro</i> evaluation of 1,4,7-triazacyclononane-coupled β-lactams against metallo-β-lactamase producing bacteria. [PDF]

RSC Adv
Shungube M, Reddy N, Ghazi T, Govender KB, Singh R, Kajee A, Chuturgoon A, Kruger HG, Arvidsson PI, Tiwari D, Govender T, Naicker T.   +11 more
europepmc   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, Volume 4, Issue 3, Page 278-292, August 2026.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Differential contribution of PBP occupancy and efflux on the effectiveness of β-lactams at their target site in clinical isolates of Neisseria gonorrhoeae. [PDF]

PLoS Pathog
López-Argüello S, Alcoceba E, Ordóñez P, Taltavull B, Cabot G, Gomis-Font MA, Oliver A, Moya B.   +7 more
europepmc   +1 more source

Evaluation of a Product Intended for Microbiological Control in Animal Production, and Its Combination With Halquinol

Animal Research and One Health, Volume 4, Issue 3, Page 302-313, August 2026.
Activo Liquid and Halquinol inhibit Salmonella and Escherichia coli in culture media. Activo Liquid exhibits bactericidal action, whereas HA is bacteriostatic, and their combination results in positive or indifferent interactions. This combination effectively inhibits E. coli throughout digestion simulation, thus reducing the required concentrations of
Alberto Gonçalves Evangelista, Lucas dos Santos Janotto, Adriana Paula Possamai, Carolina Cini Perry, Francine Lemes Ribeiro, Rafael Canonenco de Araujo, Fernando Bittencourt Luciano   +6 more
wiley   +1 more source

Dual β-lactams for the treatment of Mycobacterium abscessus: a review of the evidence and a call to act against an antibiotic nightmare. [PDF]

J Antimicrob Chemother
Longo BM, Trunfio M, Calcagno A.
europepmc   +1 more source

Successful Rapid Desensitization to Ceftazidime/Avibactam in a Patient With Cystic Fibrosis and Multidrug‐Resistant Pseudomonas aeruginosa Pneumonia: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Ceftazidime/avibactam (CAZ‐AVI) is an important therapeutic option for multidrug‐resistant (MDR) Pseudomonas aeruginosa infections; however, hypersensitivity reactions may preclude its use and create significant therapeutic challenges. We report a 21‐year‐old woman with cystic fibrosis and recurrent MDR P.
Zuoren Zhou, Jinqi Zhu, Ge Wu, Xi Kang, Qing Wang, Jie Liu, Yan Jiang   +6 more
wiley   +1 more source

Simulated achievement rate of β-lactams/nacubactam treatment in humans using instantaneous MIC-based PK/PD analysis. [PDF]

J Antimicrob Chemother
Igarashi Y, Taguchi K, Enoki Y, Chuang VTG, Matsumoto K.   +4 more
europepmc   +1 more source