Results 201 to 210 of about 740,410 (298)

Pharmacokinetics of Long‐Acting Ampicillin and Its Impact on the Gut Microbiome and Resistome in Rhesus Macaques (Macaca mulatta)

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Injectable antimicrobials with documented prolonged dosing intervals (> 48 h) for use in rhesus macaques are sparse. The objective of our study was to assess the pharmacokinetics, urine excretion, and effects on gut microbiome and resistome of intramuscular administered long‐acting formulation of ampicillin (Albipen LA) in macaques.
Annemiek Maaskant, Ingeborg M. van Geijlswijk, Mathias Devreese, Marc Cherlet, Leo F. van Geest, Jaap A. Wagenaar, Jan A. M. Langermans, Aldert L. Zomer, Jaco Bakker, Ronette Gehring   +9 more
wiley   +1 more source

Navigating the Muddled Middle: A Case-Based Exploration of Oral β-Lactams for Systemic Gram-Negative Infections. [PDF]

Open Forum Infect Dis
Shif J, Tasissa H, MacDougall C, Heil EL, Gallagher JC.   +4 more
europepmc   +1 more source

Antimicrobial prescribing guidelines for feedlot cattle

Australian Veterinary Journal, EarlyView.
P Cusack, T Batterham, SW Page, GF Browning, JM Norris   +4 more
wiley   +1 more source

Proposed Meropenem Breakpoints for Interpretation of Antimicrobial Susceptibility Testing of Bacteria Isolated From Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Meropenem is a carbapenem antibiotic used infrequently in veterinary medicine. However, antimicrobial susceptibility testing standards are needed to monitor for resistance caused by carbapenem resistant Enterobacterales (CRE). The Clinical and Laboratory Standards Institute (CLSI) does not have veterinary‐specific carbapenem breakpoints for ...
Mark G. Papich, Marilyn N. Martinez
wiley   +1 more source

<i>N</i>-Organothio β-Lactams Offer New Opportunities for Controlling Pathogenic Bacteria. [PDF]

Pathogens
Turos E.
europepmc   +1 more source

Photodynamic inactivation increases cell death rate on persistent Staphylococcus aureus

Photochemistry and Photobiology, EarlyView.
Persistent bacteria have the ability to survive extended periods of antibiotic stress by entering a metabolically dormant state. This study investigated persistence formation in two S. aureus strains and evaluated the effects of PDI using curcumin. Post‐PDI time‐kill assays conducted after metabolic recovery showed a higher rate of bacterial death ...
Maria Vitória Silva Pereira, Bruna Carolina Corrêa, Vanderlei Salvador Bagnato, Kate Cristina Blanco   +3 more
wiley   +1 more source

Continuous versus intermittent infusion of β-lactams in patients with sepsis and septic shock: a systematic review and meta-analysis. [PDF]

BMC Infect Dis
Tejada DA, García HC, Tomás-Alvarado E, Yangali-Vicente J, Rivera-Lozada O, Barboza JJ.   +5 more
europepmc   +1 more source

Medication Exposure Definitions in Perinatal Pharmacoepidemiology: Implications for Pregnancy Studies

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Exposure definitions in real‐world pregnancy studies vary across studies, data sources, treatments and outcomes, yet their impact on prevalence estimates remains unexamined. Objectives To identify the most used exposure definitions during the 1st trimester and evaluate their impact on prevalence estimates: Methods We reviewed 400 ...
Gabra Nohmie, Anick Bérard, Anton Pottegård, Mette Bliddal   +3 more
wiley   +1 more source

Durlobactam in combination with β-lactams to combat Mycobacterium abscessus. [PDF]

Antimicrob Agents Chemother
Shin E, Dousa KM, Taracila MA, Bethel CR, Nantongo M, Nguyen DC, Akusobi C, Kurz SG, Plummer MS, Daley CL, Holland SM, Rubin EJ, Bulitta JB, Boom WH, Kreiswirth BN, Bonomo RA.   +15 more
europepmc   +1 more source

1-Azetines, 1,2-Thiazetin-1,1-dioxides and Isothiazol-1,1-dioxides as Building Blocks in Heterocyclic Synthesis: the Attempted Synthesis of Bicyclic β-Sultams

This thesis is concerned with the synthesis of β-sultams and the development of new routes for the synthesis of bicyclic versions of these molecules as potential anti-bacterials.
Pitard, Arnaud
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