A mutation in RNA polymerase imparts resistance to β-lactams by preventing dysregulation of amino acid and nucleotide metabolism. [PDF]
Cell RepPatel Y, Helmann JD.
europepmc +1 more source
Acute Pustular Facial Eruption in a 5‐Year‐Old Boy
Pediatric Dermatology, EarlyView.
Naia Oillarburu +4 more
wiley +1 more source
Mutant prevention concentrations and phenotypic and genomic profiling of first-step resistance mechanisms to classical and novel β-lactams in Pseudomonas aeruginosa. [PDF]
Antimicrob Agents ChemotherSastre-Femenia MÀ +2 more
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In vitro Evaluation of the Antibacterial Activity of the Combination of Avibactam and β-Lactams Against Highly Virulent Carbapenem-Resistant <i>Klebsiella pneumoniae</i>. [PDF]
Infect Drug ResistChang J, Peng X, Wang X, Zhang Z.
europepmc +1 more source
Short, extended and continuous infusion of β-lactams: predicted impact on target attainment and risk for toxicity in an ICU patient cohort. [PDF]
J Antimicrob ChemotherSmekal AK +6 more
europepmc +1 more source
The antimycotic 5-fluorocytosine is a virulence inhibitor of uropathogenic <i>Escherichia coli</i> and eradicates biofilm-embedded bacteria synergizing with β-lactams. [PDF]
Antimicrob Agents ChemotherRavishankar S +8 more
europepmc +1 more source
The combined use of natural language processing and electronic health records data to identify historical tolerances of β-lactams and promote clinician confidence in future use. [PDF]
Health Syst (Basingstoke)Gray M, Boyce RD, Kane-Gill SL.
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Differential contribution of PBP occupancy and efflux on the effectiveness of β-lactams at their target site in clinical isolates of Neisseria gonorrhoeae. [PDF]
PLoS PathogLópez-Argüello S +7 more
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