Results 191 to 200 of about 38,167 (247)

A Lambda Red Recombinase‐Assisted CRISPR/Cas9 System for Efficient and Precise Genome Editing in Agrobacterium tumefaciens

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Agrobacterium tumefaciens is a powerful delivery tool for plant genetic transformation and a pivotal platform for agricultural biotechnology. However, laboratory strains of Agrobacterium have remained genetically unoptimized for decades, with genome engineering hindered by inefficient, endogenous homologous recombination systems.
Minmin Zheng   +4 more
wiley   +1 more source

Photoredox-catalyzed intramolecular nucleophilic amidation of alkenes with β-lactams. [PDF]

open access: yesBeilstein J Org Chem
Giraldi V   +4 more
europepmc   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

4-Oxo-β-lactams as Covalent Inhibitors of the Mitochondrial Intramembrane Protease PARL. [PDF]

open access: yesACS Med Chem Lett
Ji S   +11 more
europepmc   +1 more source

Automation of the Azapeptide Submonomer Synthesis Method

open access: yesJournal of Peptide Science, Volume 32, Issue 11, November 2026.
The solid phase submonomer azapeptide synthesis method was automated using a commercially available peptide synthesizer. Key findings for the successful automation included the use of stable isocyanate precursor for the semicarbazone installation step, elimination of all cooling steps, use of a heating block, and use of DMF as solvent.
Tyler G. Hobart   +3 more
wiley   +1 more source

Anti-microbial resistance to β-lactams and prevalence of colicin genes among phylotypes of <i>Escherichia coli</i> isolates from hedgehogs. [PDF]

open access: yesVet Res Forum
Jajarmi M   +11 more
europepmc   +1 more source

Putative cutaneous adverse drug reactions in two dogs

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary We describe two cases of cutaneous adverse drug reactions (CADR) in dogs. Case 1 presented with erythematous macules with sharply demarcated margins on the abdomen and inguinal area and depigmentation on the lip. Skin lesions appeared after 3 weeks of administration of anti‐epileptic drugs, including phenobarbital.
Je‐Seong Kwon   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy