Results 181 to 190 of about 36,552 (249)

Whole Genome Characterization of Klebsiella Strains in European Hedgehogs and Human Nosocomial Settings Identified Shared Sequence Types, Antimicrobial Resistance Genes and Plasmids

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Klebsiella pneumoniae is a pathogen associated with healthcare‐acquired infections and antimicrobial resistance (AMR) to beta‐lactams and carbapenems. Although wild animals are not typically exposed to antibiotics, they can harbour resistant strains. The European hedgehog (Erinaceus europaeus) is increasingly found in urban areas,
Biel Garcias, Chiara Seminati, Carolin M. Kobras, Samuel K. Sheppard, Rafael A. Molina‐López, Laila Darwich   +5 more
wiley   +1 more source

4-Oxo-β-lactams as Covalent Inhibitors of the Mitochondrial Intramembrane Protease PARL. [PDF]

ACS Med Chem Lett
Ji S, Bach K, Miriyala VM, Dohnálek J, Riopedre-Fernandez M, Lepšík M, van de Plassche M, Vanhoutte R, Barniol-Xicota M, Moreira R, Strisovsky K, Verhelst SHL.   +11 more
europepmc   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Amino acid substitutions in PBP3 in Haemophilus influenzae strains, their phenotypic detection and impact on resistance to β-lactams. [PDF]

J Antimicrob Chemother
Jakubu V, Cechova M, Musilek M, Malisova L, Zapletalova B, Zemlickova H.   +5 more
europepmc   +1 more source

A Standards‐Based, Cloud‐Hosted CDS System for Gonorrhea Treatment and HIV Screening

Learning Health Systems, Volume 10, Issue 4, October 2026.
ABSTRACT Objective Neisseria gonorrhoeae (or gonococcus, GC) infections have increased in incidence and antibiotic resistance, prompting updates to management guidelines. Additionally, patients with recent GC infections have been identified as a target population for human immunodeficiency virus (HIV) screening and prevention. With the rapidly changing
Edna Shenvi, Aziz Boxwala, Sarah Shaw, Andre Berro, Saugat Karki, Matthew Pooser, Jane E. Yang, Gema Dumitru, Jeanne Ocampo, Amrita Tailor, Sanjat Kanjilal, Carlos Paredes, Ritche Hao, Nitu Kashyap, David Liebovitz, Alejandro Pérez   +15 more
wiley   +1 more source

Comparative evaluation of five β-Lactamase inhibitors in combination with β-Lactams against multidrug-resistant Mycobacterium tuberculosis in vitro. [PDF]

BMC Infect Dis
Shi J, Zheng D, Su R, Ma X, Zhu Y, Wang S, Chang W, Sun D.   +7 more
europepmc   +1 more source

Comparing Chemoenzymatic and Conventional Synthetic Strategies to Wall Teichoic Acid Peptidoglycan Fragments

Israel Journal of Chemistry, Volume 66, Issue 5, September 2026.
The Gram‐positive bacteria, Staphylococcus aureus, contain wall teichoic acid (WTA, a glycopolymer (green and yellow)) is a virulence factor in their cell wall. Synthesis of the peptidoglycan‐(PG)‐WTA conjugate (blue squares) was developed via the phospho‐donor and PG acceptor (structures at the bottom right).
Min Liu, Kathleen C. Stathoulopoulos, Catherine Leimkuhler Grimes   +2 more
wiley   +1 more source

Prevalence and Characteristics of Salmonella spp. by Production Stage in Integrated Broiler Operations in Korea

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Vertically integrated broiler production systems may facilitate the dissemination of Salmonella throughout the production chain. This study demonstrates that Salmonella persists and spreads across all stages of integrated broiler production, highlighting the need for rigorous biosecurity, hygiene and continuous monitoring throughout the entire ...
Hyeong Jeong Choi, Young Ju Lee
wiley   +1 more source

A mutation in RNA polymerase imparts resistance to β-lactams by preventing dysregulation of amino acid and nucleotide metabolism. [PDF]

Cell Rep
Patel Y, Helmann JD.
europepmc   +1 more source

Sustained Tear Film Exposure After Parenteral Cefovecin Administration in Dogs: Pharmacokinetics and Relevance to Canine Bacterial Keratitis

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective To characterize the tear film pharmacokinetics of parenterally administered cefovecin (Convenia) and compare tear concentrations with the minimum inhibitory concentrations (MICs) of common ocular pathogens. Animals Studied Six healthy research‐bred Beagles.
Meredith R. McClure, Lionel Sebbag, David J. Borts, Rachel A. Allbaugh, Jessica L. Payne, Melissa A. Kubai   +5 more
wiley   +1 more source