Results 211 to 220 of about 1,666,677 (276)

Amitriptyline Induced Life‐Threatening Steven–Johnson Syndrome: Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Stevens–Johnson syndrome is one of the few dermatological emergencies in clinical practice. The syndrome is often secondary to the usage of drugs, of which allopurinol, penicillins, sulfa drugs, ibuprofen, sodium valproate, phenytoin, lamotrigine, and carbamazepine are commonly implicated.
Wondwosen Mengist Dereje, Lidya Yalew, Nardos Tafesse, Teklegiorgis Goshime Getachew   +3 more
wiley   +1 more source

A pairwise approach to revitalize β-lactams for the treatment of TB. [PDF]

Antimicrob Agents Chemother
Negatu DA, Aragaw WW, Dartois V, Dick T.
europepmc   +1 more source

A Case Series of Hypermucoid Klebsiella pneumoniae Liver Abscess in Caucasian Americans Without Travel History: An Epidemiologic Shift?

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) is an emerging cause of community‐acquired pyogenic liver abscess (PLA), classically described in East and Southeast Asia. We report two cases of hvKp‐associated PLA in Caucasian women of American origin with no history of international travel, animal exposure, or Asian food consumption. Both patients
Krishna Sai Kiran Sakalabaktula, Sameer Kumar Majety, Sri Ratna Divya Nanduri, Divya Durga, David Kreps, Devi Prasad Botu, Gopichand Muppana   +6 more
wiley   +1 more source

Short, extended and continuous infusion of β-lactams: predicted impact on target attainment and risk for toxicity in an ICU patient cohort. [PDF]

J Antimicrob Chemother
Smekal AK, Swartling M, Furebring M, Giske CG, Jönsson S, Lipcsey M, Nielsen EI.   +6 more
europepmc   +1 more source

Divergent Access to Spirocyclic and Atropisomeric Benzimidazothiazole Derivatives by Halogen‐Promoted Intramolecular Dienamine Sulfenylation

ChemistryEurope, Volume 4, Issue 3, March 2026.
A divergent halogen‐promoted intramolecular sulfenylation of dienamines enables access to two unprecedented families of benzo[4,5]imidazo[2,1‐b]thiazole. The resulting scaffolds feature distinct chiral elements, either a quaternary stereocenter in the case of spirolactones, or a stereogenic axis for heteroaryl‐alkenes, with high configurational ...
Charlou Rognan, Alexandre Gascoin, Delphine Garnier, Romain Pertschi, Nicolas Girard, Mihaela Gulea   +5 more
wiley   +1 more source

The antimycotic 5-fluorocytosine is a virulence inhibitor of uropathogenic <i>Escherichia coli</i> and eradicates biofilm-embedded bacteria synergizing with β-lactams. [PDF]

Antimicrob Agents Chemother
Ravishankar S, Conte AL, Carrasco Aliaga SJ, Baldelli V, Nielsen KL, Paroni M, Conte MP, Landini P, Rossi E.   +8 more
europepmc   +1 more source

Effect of surgical antimicrobial prophylaxis duration for colic surgery on complications and resistome

Equine Veterinary Journal, Volume 58, Issue 2, Page 390-403, March 2026.
Abstract Background Based on human studies, surgical antimicrobial (AMD) prophylaxis (SAP) beyond 24 h is unnecessary and potentially detrimental. Objective To compare clinical and microbiological outcomes in patients receiving 24‐ or 72‐h of SAP for colic surgery. Study Design Prospective randomised clinical trial.
Louise L. Southwood, Alicia Long, Jairo Perez, Scott Daniel, Kyle Bittinger, Maia Aitken, Laurel Redding   +6 more
wiley   +1 more source

Development and <i>in vitro</i> evaluation of 1,4,7-triazacyclononane-coupled β-lactams against metallo-β-lactamase producing bacteria. [PDF]

RSC Adv
Shungube M, Reddy N, Ghazi T, Govender KB, Singh R, Kajee A, Chuturgoon A, Kruger HG, Arvidsson PI, Tiwari D, Govender T, Naicker T.   +11 more
europepmc   +1 more source

Engineered Probiotics: The Next‐Generation Therapeutics to Combat Antibiotic‐Resistant Bacterial Infections

Food Frontiers, Volume 7, Issue 2, March 2026.
Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh, Raz Abdulqadir, Indira Kumari Verma, Yashika Awasthi, Arun Ratn, Juhi Sharma, Manmeet Rawat, Megh Singh Dhakad, Jasbir Dalal, Yash Gupta, Bhisham Narayan Singh, Divakar Sharma   +11 more
wiley   +1 more source

Differential contribution of PBP occupancy and efflux on the effectiveness of β-lactams at their target site in clinical isolates of Neisseria gonorrhoeae. [PDF]

PLoS Pathog
López-Argüello S, Alcoceba E, Ordóñez P, Taltavull B, Cabot G, Gomis-Font MA, Oliver A, Moya B.   +7 more
europepmc   +1 more source