Results 111 to 120 of about 51,483 (212)
Is there an association of giardiasis with beta-thalassemia minor? [PDF]
, 2010 Beta–thalassemia minor is a symptomless carrier state of a hemoglobinopathy which predisposes to bacterial infections. We report three cases presenting with giardiasis, a parasitic infection of gastrointestinal tract caused by Giardia lamblia.
Jafri, Wasim +2 more
core +1 more source
Genetics and Genomics in Sickle Cell Disease in Africa
American Journal of Hematology, Volume 101, Issue S1, Page 47-55, April 2026.ABSTRACT Advanced genomic technologies are revolutionizing our ability to understand complex diseases. Large‐scale population studies are needed to realize the potential of using individual genetic information to personalize treatments for better patient outcomes for chronic non‐communicable diseases, such as sickle cell disease (SCD).
Siana Nkya +2 more
wiley +1 more source
Non-Transfusion-Dependent Thalassemia: An Update on Complications and Management [PDF]
, 2018 Patients with non-transfusion-dependent thalassemia (NTDT) experience many clinical complications despite their independence from frequent transfusions.
Bou-Fakhredin, Rayan +5 more
core +4 more sources
Exploring Affordable Curative Therapy for Sickle Cell Disease in Africa: A Comprehensive Overview
American Journal of Hematology, Volume 101, Issue S1, Page 56-74, April 2026.ABSTRACT The practical aspects of developing curative treatments for sickle cell disease (SCD) in Africa, such as gene therapy and hematopoietic stem cell transplantation, involve strengthening healthcare infrastructure, training healthcare professionals, establishing regional treatment centers, and creating national SCD programs.
Adetola A. Kassim +2 more
wiley +1 more source
The Progress in Treatment of β-Thalassemia and Research on Animal Models of the Disease
Applied Sciencesβ-thalassemia is one of the most prevalent single-gene recessive disorders worldwide, characterized by the impaired synthesis of β-globin chains, which leads to ineffective erythropoiesis and results in anemia and iron overload, along with various ...
Shumeng Zhang +5 more
doaj +1 more source
Effect of booklet and combined method on parents' awareness of children with β-thalassemia major disorder [PDF]
, 2008 OBJECTIVE: To assess the effects of booklet and combining methods (lecture, video, etc.) on parents' awareness of children with beta-thalassemia major disorder.
Hasanpour-Dehkordi, A. +1 more
core
Macrophages support pathological erythropoiesis in Polycythemia Vera and Beta-Thalassemia [PDF]
, 2014 Regulation of erythropoiesis is achieved by integration of distinct signals. Among these, macrophages are emerging as erythropoietin-complementary regulators of erythroid development, particularly under stress conditions. We investigated the contribution
Abdel-Wahab, Omar +15 more
core +1 more source
Brain and Behavior, Volume 16, Issue 4, April 2026.Connectome predictive modeling (CPM) revealed reduced functional connectivity linked to cognitive underperformance in children with β‐thalassemia major (β‐TM), which appeared to be modulated by multiple hematological factors. ABSTRACT Purpose This study aimed to identify functional brain connectivity patterns associated with cognitive performance in ...
Shumin Xu +9 more
wiley +1 more source
Clinical manifestations of β-thalassemia major in two different altitudes; Bushehr and Shahrekord [PDF]
, 2015 Patients with β-thalassemia major (TM) develop iron overload through increased iron absorption and transfusional therapy and it’s the most important complication of TM. Thalassemia is common in coastal regions and lands with low altitudes.
Darabi, Hossein. +8 more
core +4 more sources
Journal of Clinical Laboratory Analysis, Volume 40, Issue 7, April 2026.We have developed an integrated mRNA‐based strategy for thalassemia genotyping. Its characteristics included using only three Sanger sequencing reactions to analyze the full‐length coding sequence of HBA2, HBA1 and HBB, and employing a new multiple quantitative fluorescence PCR to simply assess and present the impact of common mutations on the ...
Hongjian Chen, Qi Yao, Mianai Fu
wiley +1 more source