Results 131 to 140 of about 920,848 (226)

Diagram for the screening of hemoglobin variants, α/β-thalassemia and HPFH/δβ-thalassemia.

open access: yes, 2013
Diagram for the screening of hemoglobin variants, α/β-thalassemia and HPFH/δβ-thalassemia.
Chun-Ping Lin (285488)   +26 more
core   +1 more source

Undetectable Hydroxyurea Levels in the Majority of Sickle Cell Disease Patients, Especially in Young Children

open access: yesAmerican Journal of Hematology, Volume 101, Issue 9, Page 2297-2310, September 2026.
ABSTRACT Hydroxyurea (HU) is the most widely prescribed disease‐modifying treatment in sickle cell disease (SCD), though treatment responses vary due to metabolism and adherence. We examined HU blood levels and treatment response in patients with homozygous sickle cell disease (HbSS).
Sigrid van der Veen   +26 more
wiley   +1 more source

Severe Multiorgan Failure Triggered by Infection in an Adult With Decades of Untreated Sickle Cell Disease: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT A 67‐year‐old man with decades of untreated sickle cell disease developed septic shock with multiorgan failure, splenic infarction, and marrow fibrosis; his genotype could not be confirmed. He recovered with intensive supportive care, with hydroxyurea initiated for long‐term disease modification, illustrating catastrophic infection‐triggered ...
Sara Shahidi, Gisha Mohan
wiley   +1 more source

Frequency of heart complication in beta thalassemia major children at tertiary care hospital

open access: yesJournal of Contemporary Pharmacy
Objective: to evaluate the prevalence of cardiac problems, including myocardial iron deposition, pericarditis, and valvular abnormalities, among people with β-thalassemia and to shed light on the distribution of β-thalassemia and hemoglobin levels ...
Ammad Ali   +7 more
doaj   +2 more sources

Effects of Zinc Supplementation on Glycemic Control, Insulin Resistance, Inflammation and Oxidative Stress in Diabetes: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Zinc supplementation in diabetes is associated with improved insulin sensitivity, lipid profile, antioxidant status and reduced inflammation, without significant effects on glycemic indices. Overall, evidence from randomized trials supports zinc as a beneficial metabolic adjunct with moderate‐to‐high certainty. ABSTRACT Objectives Diabetes mellitus (DM)
Jessica Paola Loaiza‐Giraldo   +15 more
wiley   +1 more source

Inherited microcytic anemias due to disorders of iron and heme metabolism: An updated clinical review

open access: yesHemaSphere, Volume 10, Issue 9, September 2026.
Abstract Microcytic anemia is among the most common hematological abnormalities in clinical practice and is usually attributable to iron deficiency, thalassemia traits, or anemia of inflammation. A small but clinically important subset of patients, however, has inherited disorders of iron metabolism or heme synthesis presenting with persistent ...
Alexandros Makis   +2 more
wiley   +1 more source

Beta Thalassemia and Chronic Myeloid Leukemia: Dual Diagnosis Under the Microscope

open access: yes
International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 931-933, October 2026.
Paige Muir   +3 more
wiley   +1 more source

Academic Performance Among Children With Sickle Cell Disease in Low‐ and Middle‐Income Countries: A Systematic Review

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aim Children with sickle cell disease (SCD) in low‐ and middle‐income countries (LMICs) face significant disease‐related challenges and socioeconomic status (SES) disparities that may negatively impact their academic performance. This systematic review synthesized existing evidence on academic performance among children with SCD
Shubaya K. Naggayi   +7 more
wiley   +1 more source

Contemporary Management of Thalassemia: A Perspective on Current Standards and the Emergence of FDA‐Approved Oral Therapy

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Thalassemia is an inherited hemoglobin disorder characterized by ineffective erythropoiesis, chronic anemia, and progressive multisystem complications that require lifelong management. Current treatment relies on regular red blood cell transfusions, iron chelation therapy, and supportive multidisciplinary care, while ...
Fnu Zainab   +3 more
wiley   +1 more source

Analysis of thalassemia genotypes and HbA2 test results in pregnant women in Shenzhen, China

open access: yesScientific Reports
To examine the thalassemia genotypes and distribution among pregnant women in Shenzhen, as well as the diagnostic value of HbA2 in thalassemia screening, in order to provide scientific evidence for thalassemia prevention and control in this region.
Hou Qian   +7 more
doaj   +1 more source

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