Results 111 to 120 of about 920,848 (226)
A global survey of blood transfusion practices for patients with sickle cell disease
Abstract Background Sickle cell disease (SCD) affects over 7 million people globally, with blood transfusion remaining a cornerstone of management. However, contemporary transfusion practices across diverse settings remain poorly characterized. We evaluated global transfusion practices for patients with SCD to identify gaps and inform resource ...
Jeremy W. Jacobs +18 more
wiley +1 more source
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna +16 more
wiley +1 more source
Hematological ratios and cytokine profiles in heterozygous beta-thalassemia
Introduction: β-Thalassemia is defined by a reduced or complete absence of β-globin chain synthesis in hemoglobin, leading to hemolytic anemia. Heterozygous β-thalassemia, also known as β-thalassemia trait (hBTh), the mildest form of this anemia ...
Ana Carolina Marques Ciceri +11 more
doaj +1 more source
ABSTRACT Third allogeneic hematopoietic stem cell transplantation (HSCT3) is rarely performed in pediatric patients and is associated with high toxicity and mortality. Data on outcomes in this setting remain scarce. We conducted a retrospective multicenter study within the Spanish GETH‐TC Pediatric group including 29 children and adolescents who ...
Luisa Sisinni +17 more
wiley +1 more source
HUBUNGAN GAMBARAN DERMATOGLIFI DENGAN PENYAKIT β - THALASSEMIA MAJOR [PDF]
Nisa’u Luthfi Nur Azizah, G0011151, 2015. Hubungan Gambaran Dermatoglifi dengan Penyakit β – Thalassemia Major. Skripsi Fakultas Kedokteran Universitas Sebelas Maret Surakarta.
Azizah, Nisa'u Luthfi Nur
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The pregnancy outcome in patients with minor β-thalassemia [PDF]
Background: β-thalassemia is the most common hereditary disease in Iran and more than 2 million carriers of the β-thalassemia mutant gene are living in this country. Objective: To determine pregnancy outcome of women with β-thalassemia minor.
Amooeel, Sedigheh +3 more
core +3 more sources
ABSTRACT Sickle cell disease (SCD) is characterized by both acute and chronic complications. The clinical manifestation of these complications differs between genotypes. Given the large amount of research already published, this systematic review aims to offer a complete overview of types of sickle cell complications between adults in the most common ...
Martijn van der Meer +3 more
wiley +1 more source
The correlation between HLA class II and β-thalassemia major in Al-Karama teaching hospital
Background: Thalassemia is a form of inherited autosomal recessive blood disorder characterized by abnormal formation of hemoglobin. Objective: Determine frequencies & association of HLA class II alleles (DRB1& DQB1) in Iraqi β-thalassemia major patients.
Sarmad M. Zeiny
doaj +1 more source
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang +9 more
wiley +1 more source
Evaluation of physical growth of Patient WithThalassemia Major Based on NCHS criteria [PDF]
Background: Beta thalassemia major, including the conditions in which the natural growth due to complications from those diseases can be disrupted. Despite the recent advances in treating these patients, growth retardation in a significant percentage of ...
آریش, گیتی +4 more
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