Results 121 to 130 of about 51,483 (212)

Irreversible thermal denaturation of human carbonic anhydrase [PDF]

open access: yes
Carbonic Anhydrase (CA; carbonate hydro-lyase, EC 4.2.1.1)), a zinc containing enzyme, catalyzes reversible hydration of carbon dioxide. This metalloenzyme is found in animals, photosynthesizing organisms, and in some nonphotosynthetic bacteria. Thermal
امانی, مجتبی   +4 more
core  

Global Burden of Sickle Cell Disease: Adequacy of Pain Control as Evidenced by Frequency of Oral Pain Medication Use, Health Outcomes, and Emotional Well‐Being Across Diverse Populations

open access: yeseJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Introduction Sickle cell disease (SCD) is a chronic genetic disorder causing severe pain, anemia, and systemic complications that negatively affect patients’ physical and mental well‐being. The aim of this global cross‐sectional study was to evaluate the relationship between oral pain medication (OPM) use frequency and health outcomes ...
Akshat Jain, Lisa Roberts, Safiye Sahin
wiley   +1 more source

Chronic hyperplastic anemia as an independent risk factor for atherosclerotic lesions: a lesson from thalassemia intermedia [PDF]

open access: yes, 2010
Introduction. Cardiovascular involvement represents a well-known complication and the primary cause of mortality, both in transfusion-dependent beta thalassemia major (β-TM) and in transfusion-independent beta thalassemia intermedia (β-TI ...
Alessandra Spiga   +7 more
core   +1 more source

Effect of Tonsillar Retractor on Intracranial and Intraocular Pressure in Children Undergoing Adenotonsillectomy Surgeries

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 2, April 2026.
The effect of tonsillar retractor placement on IOP and ONSD values. ABSTRACT Objectives The tonsillar retractor used during adenotonsillectomy, one of the most common pediatric surgeries, may increase sympathetic activity. This study aimed to evaluate the effect of tonsillar retractor insertion on intracranial pressure (ICP) and intraocular pressure ...
Ayse Bozkurt Oflaz   +5 more
wiley   +1 more source

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 2, Page 295-304, April 2026.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

ACMG/AMP‐Based Variant Classification of a Novel HBA2 Variant (HBA2: C.297del, Hb Taiping) in Compound Heterozygosity With Hb Adana (HBA2:C.179G>A) Causing Non‐Deletional Hb H Disease

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 2, Page 458-465, April 2026.
ABSTRACT Background Accurate classification of novel globin gene variants is critical for the diagnosis and management of thalassaemia. The adaptation of ACMG/AMP guidelines for globin genes represents an important step toward standardising variant interpretation and enhancing clinical utility in the field.
Norafiza Mohd Yasin   +14 more
wiley   +1 more source

Prevalence of renal tubular dysfunction in beta thalassemia minor in shiraz [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2011
Background & objective: β-Thalassemia minor is an asymptomatic hereditary disease. The first study on the relation of renal tubular dysfunction and β-thalassemia minor was performed in 2002 but those studies seem inadequate.The main goal of this study is
  +2 more
doaj  

Study of Pregnancy Outcome in E-Beta Thalassaemia Mothers [PDF]

open access: yes, 2009
Forty eight E-Beta thalassaemia patients were studied in NRS Medical College, Kolkata, West Bengal during the period from 2000-2006. In all patients Hb% ranged from 5.2g% - 9.6g%.
Bhattacharyaya, Maitryaee   +1 more
core   +1 more source

Antimicrobial and Cytotoxic Activities of Biogenic Nanoparticles Produced by Cyanobacteria

open access: yesChemBioChem, Volume 27, Issue 5, 13 March 2026.
The article reviews the green synthesis of biogenic nanoparticles produced by cyanobacteria, highlighting their antimicrobial and cytotoxic properties. These nanoparticles, formed intra‐ or extracellularly, show activity against Gram‐positive and Gram‐negative bacteria as well as fungi and can induce apoptosis in tumor cells.
Laíne Santos Ribeiro   +4 more
wiley   +1 more source

موتاسيون‌های نادر و کم‌شيوع بتاتالاسمی در استان قزوين-ايران [PDF]

open access: yes, 2009
زمينه و هدف: حدود 13 موتاسيون بتاگلوبين، 90-70% طيف ملکولی تالاسمی‌ها را در ايران تشکيل می‌دهند که به نام موتاسيون‌های شايع بتاگلوبين خوانده می‌شوند. مابقی موتاسيون‌ها به نام نادر يا ناشناخته معروف هستند.
احمدی, محمدحسین   +2 more
core  

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