Results 61 to 70 of about 2,697,911 (252)
Annals of Global Health, 2021 Background: Blood transfusion is a traditional treatment for β-thalassemia (β-thal) that improves the patients’ anemia and lifespan, but it may lead to iron overload in parenchymal tissue organs and endocrine glands that cause their dysfunctions as the ...
M. Arab-zozani +3 more
semanticscholar +1 more source
An overview of current treatment strategies for β-thalassemia [PDF]
, 2014 Introduction: At least 40,000 people per year worldwide are born with β-thalassemia. Patients with β-thalassemia major are reliant on regular red blood cell transfusions for survival from a young age. For those with β-thalassemia intermedia or hemoglobin
Cappellini, Maria Teresa +5 more
core +1 more source
Clinical and Laboratory Study of Sickle Cell/β-Thalassemia [PDF]
, 1986 We have studied 39 patients doubly heterozygous for sickle cell/β-thalassemia, 12 with sickle cell/βo- thalassemia and 27 with sickle cell/β+-thalassemia. Generally, sickle cell/βo-thalassemia is considered more severe than sickle cell/β+-thalassemia. In
Maeda, Koichi +2 more
core +1 more source
Thalassemia Reports, 2022 This is a report of a couple with abnormal hematological indices who were investigated for α & β-thalassemia mutations. Based on CBC and capillary hemoglobin electrophoresis results, the male and female subjects were β & α-thalassemia carriers ...
Hossein Jalali +3 more
doaj +1 more source
Evaluation of the combination therapy of hydroxyurea and thalidomide in β-thalassemia
Blood Advances, 2022 Key Point • The use of Hu and thalidomide combination in β-thalassemia resulted in fewer transfusions and increased Hb levels.
S. Ansari +11 more
semanticscholar +1 more source
Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512), 2017 A representative sample of a thousand volunteer university students was screened for evidence of thalassemia minor.Complete blood counts using automated blood cell analysers and blood smears were examined. Patients having anemia, abnormal red cell indices or morphological features of thalassemia minor like hypochromia, microcytosis, target ...
Abdulkadir A. Alnakshabandi +1 more
openaire +3 more sources
Redox Balance in β-Thalassemia and Sickle Cell Disease: A Love and Hate Relationship
Antioxidants, 2022 β-thalassemia and sickle cell disease (SCD) are inherited hemoglobinopathies that result in both quantitative and qualitative variations in the β-globin chain.
R. Bou-Fakhredin +5 more
semanticscholar +1 more source
The Associations between HLA DQB1 different Alleles and β-thalassemia Major [PDF]
Minia Journal of Medical Research, 2020 Thalassemias are the commonest inherited hemoglobinopathies in the world. Approximately 68,000 children are born with various thalassemia syndromes each year. β-Thalassemia represents a major public health problem in Egypt. beta thalassemia. It is caused
Amel Kamal Eldin +3 more
doaj +1 more source
TIF Guidelines for the Management of Transfusion‐Dependent β‐Thalassemia
HemaSphereThe prospect of patients with transfusion ‐ dependent β ‐ thalassemia (TDT), once considered a fatal childhood disorder, has completely transformed over the past 50 years.
K. Musallam +6 more
semanticscholar +1 more source
Molecular genetics of β-thalassemia
Medicine, 2021 β-thalassemia is a hereditary hematological disease caused by over 350 mutations in the β-globin gene (HBB). Identifying the genetic variants affecting fetal hemoglobin (HbF) production combined with the α-globin genotype provides some prediction of ...
T. Jaing +5 more
semanticscholar +1 more source