Results 1 to 10 of about 32,475 (118)
Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial [PDF]
Nature Communications, 2023 β2-agonist treatment improves skeletal muscle glucose uptake and whole-body glucose homeostasis in rodents. Here the authors report that two-weeks of treatment with the β2-agonist clenbuterol improves insulin-stimulated glucose disposal in healthy young ...
Sten M. M. van Beek +17 more
doaj +2 more sources
Wheezing Characteristics and Predicting Reactivity to Inhaled β2-Agonist in Children for Home Medical Care [PDF]
Frontiers in Pediatrics, 2021 Background: Given that wheezing is treated with inhaled β2-agonists, their effect should be reviewed before the condition becomes severe; however, few methods can currently predict reactivity to inhaled β2-agonists.
Chizu Habukawa +6 more
doaj +2 more sources
PLoS ONE, 2022 IntroductionPrevious observational studies assessing β2-agonist/-antagonist use on PD risk have yielded conflicting results. We evaluated the relationship between β2-agonist use and the incidence of Parkinson's disease in patients with chronic lung ...
Hasan Nadeem +3 more
doaj +2 more sources
Activation of β2-adrenergic Receptor Alleviates Collagen-induced Arthritis by Ameliorating Th17/Treg Imbalance [PDF]
Iranian Journal of Immunology, 2023 Background: Recent research in our laboratory shows that CD4+ T cells express the β2 adrenergic receptor (β2-AR), and the sympathetic neurotransmitter norepinephrine regulates the function of T cells via β2-AR signaling.
Jian-Hua Lu +5 more
doaj +1 more source
Clinical and Translational Medicine, 2022 Background Vascularized composite tissue allotransplantation (VCA) to replace limbs or faces damaged beyond repair is now possible. The resulting clear benefit to quality of life is a compelling reason to attempt this complex procedure.
Minhyung Kim +6 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Rheumatoid arthritis and osteoarthritis overlap many molecular mechanisms of cartilage destruction. Wear and tear in cartilage is chondrocyte-mediated, where chondrocytes act both as effector and target cells.
Iqra Ajmal +5 more
doaj +1 more source
Low Expression in Xenopus Oocytes and Unusual Functional Properties of α1β2γ2 GABAA Receptors with Non-Conventional Subunit Arrangement. [PDF]
PLoS ONE, 2017 The major subunit isoform of GABAA receptors is α1β2γ2. The subunits are thought to surround an ion pore with the counterclockwise arrangement α1γ2β2α1β2 as seen from the outside of the neuron. These receptors have two agonist sites and one high affinity
Roland Baur, Erwin Sigel
doaj +1 more source
Biomedicines, 2022 The sympathetic nervous system (SNS) has either a pro-inflammatory or anti-inflammatory effect, depending on the stage of arthritis. In the past, treatment of arthritic B cells with a β2-adrenergic receptor (β2-ADR) agonist has been shown to attenuate ...
Nadine Honke +2 more
doaj +1 more source
Frontiers in Oncology, 2022 Infantile hemangioma (IH) is a benign vascular tumor, characterized by a unique sequence of non-linear growth and spontaneous involution. Some hemangiomas require intensive treatment to avoid functional and aesthetic insufficiency.
Qiang Chen +7 more
doaj +1 more source
Allosteric modulator potentiates β2AR agonist–promoted bronchoprotection in asthma models
The Journal of Clinical Investigation, 2023 Asthma is a chronic inflammatory disease associated with episodic airway narrowing. Inhaled β2-adrenergic receptor (β2AR) agonists (β2-agonists) promote — with limited efficacy — bronchodilation in asthma.
Seungkirl Ahn +7 more
doaj +1 more source