Results 131 to 140 of about 1,820,241 (196)

The κ-opioid receptor-induced autophagy is implicated in stress-driven synaptic alterations. [PDF]

Front Mol Neurosci, 2022
Karoussiotis C, Sotiriou A, Polissidis A, Symeonof A, Papavranoussi-Daponte D, Nikoletopoulou V, Georgoussi Z.   +6 more
europepmc   +1 more source

Systemic κ-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats

, 2010
Altered dynorphin opioid peptide systems contribute to increased ethanol self-administration during withdrawal following chronic alcohol exposure. We previously identified that the κ-opioid receptor antagonist nor-binaltorphimine (nor-BNI) selectively ...
George F. Koob, Zorrilla, Eric P, Walker, Brendan M, Eric P. Zorrilla, Koob, George F, Brendan M. Walker   +5 more
core   +1 more source

Isosteric Replacement of Acidic with Neutral Residues in Extracellular Loop-2 of the κ-Opioid Receptor Does Not Affect Dynorphin A(1−13) Affinity and Function

, 2016
Isosteric Replacement of Acidic with Neutral Residues in Extracellular Loop-2 of the κ-Opioid Receptor Does Not Affect Dynorphin A(1−13) Affinity and ...
Stacy Kramer (3024504), Ping Y. Law (3014367), David M. Ferguson (390575), Philip S. Portoghese (1330458), Thomas G. Metzger (3010200)   +4 more
core   +1 more source

Developmental Expression of the μ, κ, and δ Opioid Receptor mRNAs in Mouse

, 1998
To characterize further the establishment of the opioid system during prenatal mouse development, we have examined the spatial and temporal expression patterns of μ, κ, and δ opioid receptor mRNAs and find that the expression patterns of these mRNAs are ...
Yanxin Zhu, John E. Pintar, Ming-Sing Hsu   +2 more
core   +1 more source

Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects. [PDF]

Molecules, 2023
Santino F, Gentilucci L.
europepmc   +1 more source

The claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology. [PDF]

Nat Commun, 2023
Wang YJ, Zan GY, Xu C, Li XP, Shu X, Yao SY, Xu XS, Qiu X, Chen Y, Jin K, Zhou QX, Ye JY, Wang Y, Xu L, Chen Z, Liu JG.   +15 more
europepmc   +1 more source

Author Correction: Amygdala dynorphin/κ opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress. [PDF]

Acta Pharmacol Sin, 2023
Zan GY, Sun X, Wang YJ, Liu R, Wang CY, Du WJ, Guo LB, Chai JR, Li QL, Liu ZQ, Liu JG.   +10 more
europepmc   +1 more source

Discovery of κ Opioid Receptor (KOR)-Selective d-Tetrapeptides with Improved In Vivo Antinociceptive Effect after Peripheral Administration. [PDF]

ACS Med Chem Lett, 2022
Stefanucci A, Della Valle A, Scioli G, Marinaccio L, Pieretti S, Minosi P, Szucs E, Benyhe S, Masci D, Tanguturi P, Chou K, Barlow D, Houseknecht K, Streicher JM, Mollica A.   +14 more
europepmc   +1 more source

Plant-Derived Cyclotides Modulate κ-Opioid Receptor Signaling. [PDF]

J Nat Prod, 2021
Muratspahić E, Tomašević N, Nasrollahi-Shirazi S, Gattringer J, Emser FS, Freissmuth M, Gruber CW.   +6 more
europepmc   +1 more source

The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic Pain Through the Ca²⁺/CaMKII/CREB Pathway in Rats. [PDF]

J Inflamm Res, 2022
Zhang XM, Lun MH, Du W, Ma F, Huang ZQ.
europepmc   +1 more source