Results 161 to 170 of about 9,643 (193)

Synthesis and Pharmacological Evaluation of Fluorinated Quinoxaline-Based κ-Opioid Receptor (KOR) Agonists Designed for PET Studies. [PDF]

ChemMedChem, 2020
Tangherlini G, Börgel F, Schepmann D, Slocum S, Che T, Wagner S, Schwegmann K, Hermann S, Mykicki N, Loser K, Wünsch B.   +10 more
europepmc   +1 more source

Hypoxia Induces Internalization of κ-Opioid Receptor

, 2017
Chunhua Xi, Xuan Liang, Chunhua Chen, Hasan Babazada, Tianzuo Li, Renyu Liu   +5 more
openalex   +1 more source

[Clinical Research Progress on Using κ-Opioid Receptor Agonists to Treat Uremic Pruritus]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Yang M, Li Y, Yang Q, Su B.
europepmc   +1 more source

Docking 14 Million Virtual Isoquinuclidines against the μ and κ Opioid Receptors Reveals Dual Antagonists–Inverse Agonists with Reduced Withdrawal Effects

Seth F. Vigneron, Shohei Ohno, Joao Bráz, Joseph Kim, Oh Sang Kweon, Chase M. Webb, Christian B. Billesbølle, Karthik Srinivasan, Karnika Bhardwaj, John J. Irwin, Aashish Manglik, Allan I. Basbaum, Jonathan A. Ellman, Brian K. Shoichet   +13 more
openalex   +1 more source

Structural determinants of diphenethylamines for interaction with the κ opioid receptor: Synthesis, pharmacology and molecular modeling studies

, 2016
Elena Guerrieri, Marcel Bermúdez, Gerhard Wolber, Ilona P. Berzetei‐Gurske, Helmut Schmidhammer, Mariana Spetea   +5 more
openalex   +1 more source

Pharmacologic Characterization of Substituted Nitazenes at μ, κ, and Δ Opioid Receptors Suggests High Potential for Toxicity [PDF]

Laura B. Kozell, Amy J. Eshleman, Katherine M. Wolfrum, Tracy L. Swanson, Shelley H. Bloom, Sheila Benware, Jennifer L. Schmachtenberg, Kamryn A. Schutzer, William E. Schutzer, Aaron Janowsky, Atheir I. Abbas   +10 more
openalex   +1 more source

Aticaprant: (a κ-opioid receptor antagonist) for major depressive disorder

Elliot Hampsey, Luke A. Jelen, Allan H. Young   +2 more
openalex   +2 more sources

Data Sheet 1_Efficacy and safety of peripherally-restricted κ-opioid receptor agonist-HSK21542 for postoperative analgesia in patients undergoing laparoscopic abdominal surgery: a randomized, placebo-controlled phase 2 trial.pdf

Yinbo Zhong (17332877), Haiying Wang (6869), Min Yan (119568), Mengchang Yang (3697633), Jiaqiang Zhang (6715844), Ling Nan (21776249), Zhiping Wang (38478), Jianjun Yang (124022), Jinglei Wu (1530298), Qulian Guo (146481), Xiaoling Hu (5499059), Hongmeng Xu (21776252), Qiang Xu (71522), Dongxin Wang (4630951)   +13 more
openalex   +1 more source

Differential effects of sodium on agonist-induced conformational transitions and signaling at μ and κ opioid receptors [PDF]

Bryan L. Roth, Bram Kuijer, Camryn J. Fulton, T. Albert, Paloma M. Knobloch, Jing Wang, B. Krumm, Tao Che, Balázs R. Varga, Susruta Majumdar, Vsevolod Katritch, Ryan H. Gumpper, Terry Kenakin, Xi‐Ping Huang   +13 more
openalex   +1 more source

Pharmacological activities of optically pure enantiomers of the κ opioid agonist, U50,488, and its cis diastereomer: evidence for three κ receptor subtypes

, 1989
Richard B. Rothman, Charles P. France, Victor Bykov, Brian R. de Costa, Arthur E. Jacobson, James H. Woods, Kenner C. Rice   +6 more
openalex   +2 more sources