Results 161 to 170 of about 9,562 (190)

Dynorphin peptides differentially regulate the human κ opioid receptor

, 2007
Yong Chen, Chongguang Chen, Lee‐Yuan Liu‐Chen   +2 more
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Aticaprant: (a κ-opioid receptor antagonist) for major depressive disorder

Elliot Hampsey, Luke A. Jelen, Allan H. Young   +2 more
openalex   +2 more sources

Docking 14 Million Virtual Isoquinuclidines against the μ and κ Opioid Receptors Reveals Dual Antagonists–Inverse Agonists with Reduced Withdrawal Effects

Seth F. Vigneron, Shohei Ohno, João Braz, Joseph Kim, Oh Sang Kweon, Chase M. Webb, Christian B. Billesbølle, Karthik Srinivasan, Karnika Bhardwaj, John J. Irwin, Aashish Manglik, Allan I. Basbaum, Jonathan A. Ellman, Brian K. Shoichet   +13 more
openalex   +1 more source

Pharmacological activities of optically pure enantiomers of the κ opioid agonist, U50,488, and its cis diastereomer: evidence for three κ receptor subtypes

, 1989
Richard B. Rothman, Charles P. France, Victor Bykov, Brian R. de Costa, Arthur E. Jacobson, James H. Woods, Kenner C. Rice   +6 more
openalex   +2 more sources

Differential effects of sodium on agonist-induced conformational transitions and signaling at μ and κ opioid receptors [PDF]

Bryan L. Roth, Bram Kuijer, Camryn J. Fulton, T. Albert, Paloma M Knobloch, Jing Wang, B. Krumm, Tao Che, Balázs R. Varga, Susruta Majumdar, Vsevolod Katritch, Ryan H. Gumpper, Terry Kenakin, Xi‐Ping Huang   +13 more
openalex   +1 more source

Data Sheet 1_Efficacy and safety of peripherally-restricted κ-opioid receptor agonist-HSK21542 for postoperative analgesia in patients undergoing laparoscopic abdominal surgery: a randomized, placebo-controlled phase 2 trial.pdf

Yinbo Zhong (17332877), Haiying Wang (6869), Min Yan (119568), Mengchang Yang (3697633), Jiaqiang Zhang (6715844), Ling Nan (21776249), Zhiping Wang (38478), Jianjun Yang (124022), Jinglei Wu (1530298), Qulian Guo (146481), Xiaoling Hu (5499059), Hongmeng Xu (21776252), Qiang Xu (71522), Dongxin Wang (4630951)   +13 more
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Presynaptic Mechanism for Anti-Analgesic and Anti-Hyperalgesic Actions of κ-Opioid Receptors

, 2003
Bihua Bie, Zhizhong Z. Pan
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κ-Opioid Receptor Modulation of GABAergic Inputs onto Ventrolateral Periaqueductal Gray Dopamine Neurons. [PDF]

Mol Neuropsychiatry, 2019
Li C, Kash TL.
europepmc   +1 more source

G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons. [PDF]

Sci Signal, 2018
Ho JH, Stahl EL, Schmid CL, Scarry SM, Aubé J, Bohn LM.   +5 more
europepmc   +1 more source

The κ-Opioid Receptor Agonist Nalfurafine Enhances the Chemotherapy-induced Survival Advantage in Pancreatic Cancer-bearing Mice

, 2017
Yusuke Hamada, Yoshihiko Tasaki, K. Morita, Kohei Yamamizu, Michiko Narita, Fukiko Matsuyama, Masami Suzuki, Daigo Ikegami, Kazuhiko Arakawa, Yasuyuki Nagumo, Miho Kawata, Yasuhito Uezono, Hiroshi Nagase, Kazunori Aoki, Jun K. Yamashita, Naoko Kuzumaki, Minoru Narita   +16 more
openalex   +1 more source