κ-Opioid Receptor Modulation of GABAergic Inputs onto Ventrolateral Periaqueductal Gray Dopamine Neurons. [PDF]
Li C, Kash TL.
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G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons. [PDF]
Ho JH+5 more
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κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway. [PDF]
Cui Y+15 more
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Development and In Vivo Evaluation of a κ-Opioid Receptor Agonist as a PET Radiotracer with Superior Imaging Characteristics. [PDF]
Li S+7 more
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Negative modulation of spinal κ-opioid receptor-mediated antinociception by the µ-opioid receptor at selective doses of (-)-pentazocine. [PDF]
Robinson DL, Nag S, Mokha SS.
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Design, Synthesis and Pharmacological Evaluation of Novel Endomorphin Analogues with Multiple Structural Modifications [PDF]
Mallareddy Jayapal Reddy
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Review of the potential health impact of ß-casomorphins and related peptides: Report of the DATEX Working Group on ß-casomorphins [PDF]
FitzGerald, R.J.+7 more
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Mechanism of direct Cav2.2 channel block by the κ-opioid receptor agonist U50488H
Neuropharmacology, 2016U50488H is a benzeneacetamide κ-opioid receptor (κ-OR) agonist analgesic, widely used for investigating the pharmacology of G protein-coupled κ-ORs. However, U50488H is also known to directly block various voltage-gated ion channels in a G protein-independent manner.
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