Results 21 to 30 of about 411 (100)

Analysis of associations between pharmacodynamic genetic factors and antipsychotics’ effectiveness and safety in adolescents with acute psychotic episodes taking antipsychotics during a 28-day follow-up

open access: yesКачественная клиническая практика, 2021
Introduction. Antipsychotics are the main drugs for treatment of schizophrenia spectrum disorders. Pharmacodynamic genetic factors are being actively studied to improve the accuracy of antipsychotic selection based on pharmacogenetic testing.
D. V. Ivaschenko   +11 more
doaj   +1 more source

Associations of CYP2D6, ABCB1 2677G>T/A and 3435C>T with effectiveness and safety of pharmacotherapy for acute psychotic episodes in adolescents over 28 days

open access: yesКачественная клиническая практика, 2021
Introduction. Pharmacokinetic genetic factors are prognostically relevant when prescribing antipsychotics to adult patients. Currently, there is a dearth of research on adolescents with an acute psychotic episode. Aim.
D. V. Ivaschenko   +10 more
doaj   +1 more source

Сочетание алкогольнойзависимости и депрессии:трудности и особенности терапии

open access: yesСовременная терапия психических расстройств, 2017
Депрессия встречается у 25–40 % пациентов с алкогольной зависимостью (АЗ). Несмотря на эффективность фармакотерапии при раздельно существующих АЗ и депрессии, применение лекарственных средств при коморбидной патологии недостаточно протестировано и ...
Николишин, Е.   +4 more
doaj   +1 more source

Фармакогенетика и индивидуализированный подход к терапии бронхиальной астмы

open access: yes, 2017
Bronchial asthma is a chronic inflammatory disease of the airways. Ineffective treatment can significantly reduce the quality and duration of life of the patients.
Иван Иванович Балаболкин   +3 more
semanticscholar   +1 more source

Pharmacogenetics of hypoglycemic agents [PDF]

open access: yes, 2015
Despite the increase in the number of hypoglycemic agents, 35%–40% of patients with diabetes are unable to achieve adequate glycemic control. One of the reasons is the genetic heterogeneity of diabetes mellitus, requiring different treatment approaches ...
Aleksandr Yuryevich Mayorov   +3 more
core   +3 more sources

ФАРМАКОГЕНЕТИКА ОСНОВНЫХ ПРЕДСТАВИТЕЛЕЙ ТРАНСПОРТЕРОВ ОРГАНИЧЕСКИХ КАТИОНОВ

open access: yes, 2018
This article describes basic information about the classification, structure, substrate specificity and expression of organic cation transporters. The pharmacokinetic and pharmacogenetic aspects of transporters are discussed in more detail, as well as ...
Владимир Александрович Евтеев   +3 more
semanticscholar   +1 more source

PHARMACOGENETIC ASPECTS OF THE USE OF PERIOPERATIVE DRUGS IN PEDIATRICS. Review [PDF]

open access: yes, 2022
Relevance. It is known that in children the frequency of perioperative critical events due to the introduction of drugs is more than 5%. For example fentanyl, which is used as an adjunct to surgical anesthesia, is a major factor in increasing the number ...
M.V. Khaitovych   +2 more
core   +2 more sources

Фармакогенетика антитромботических препаратов: современное состояние проблемы

open access: yes, 2018
The review deals with the main trials devoted to the study of genetic markers of individual variability in drug response to antithrombotic agents. The first part describes the studies of the genes encoding the platelet receptor subunits studied in the ...
Е. С. Кропачева
semanticscholar   +1 more source

Фармакогенетика антиэпилептических препаратов [PDF]

open access: yes, 2008
There are some generalized data on a problem pharmacogenetics researches antiepileptic drugs on the basis of the analysis of the accessible native and foreign literature in this review.В настоящем обзоре на основе анализа отечественной и зарубежной ...
D. V. Dmitrenko   +5 more
core   +2 more sources

APPLICATIONS OF PHARMACOGENETIC TESTING FOR PERSONALIZATION OF THERAPY WITH ORAL ANTICOAGULANTS IN RUSSIA

open access: yesРациональная фармакотерапия в кардиологии, 2015
The clinical significance of the patient genetic characteristics in the individual pharmacological response to oral anticoagulants is considered. Possible tactics of warfarin dosing and new oral anticoagulants choice on the basis of pharmacogenetic ...
D. A. Sychev   +3 more
doaj   +1 more source

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