Results 31 to 40 of about 45 (45)

Pharmacogenetics of Antidepressants: from Genetic Findings to Predictive Strategies

Acta Biomedica Scientifica, 2019
The constantly growing contribution of depressive disorders to the global disease statistics calls for a growth of treatment effectiveness and optimization. Antidepressants are the most frequently prescribed medicines for depressive disorders.
L. K. Khokhlov, N. E. Lukyanov
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Клиническая фармакогенетика: тернистый путь внедрения в клиническую практику

Качественная клиническая практика, 2018
Один из путей повышения эффективности и безопасности лекарственных средств - персонализированная медицина.

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Artificial intelligence in pharmacogenetics: A narrative review of current and future applications

Acta Biomedica Scientifica
Pharmacogenetics aims to investigate the correlation between patient genetic characteristics and the efficacy of pharmaceutical agents, while concurrently evaluating the risks of adverse reactions.
M. A. Abdullaev, B. I. Kantemirova, O. A. Bashkina, D. A. Sychev, O. V. Ivanchuk, A. N. Romanova   +5 more
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PREVALENCE OF POLYMORPHOUS LOCUS 681G>A OF CYP2C19 GENE IN RUSSIAN POPULATION

Acta Biomedica Scientifica, 2014
The prevalence of genotypes and alleles of polymorphous locus 681G>A of CYP2C19 gene in Russian population of Eastern Siberia. We conducted comparative analysis of response characteristics with previous data of other world's populations.
T. A. Bairova, S. A. Churbanova, S. I. Kovesnikov, O. V. Kalyuzhnaya   +3 more
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Фармакогенетика в анестезиологии: на что стоит обратить внимание

Вестник интенсивной терапии, 2021
Индивидуальные фармакогенетические особенности пациентов в настоящее время активно изучаются в различных областях медицины, и анестезиология не является исключением.
Олег Андреевич Махарин, В. М. Женило, А. А. Бычков   +2 more
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Перспективы для клинического фармаколога

Качественная клиническая практика, 2018
Клиническая фармакология как отдельная область медицины существует уже более 40 лет и занимается изучением самых различных проблем лекарственной терапии, начиная с методологии клинических испытаний и метаболизма лекарственных средств (с начала 60-х гг ...

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Pharmacogenetic aspects of substance use disorders

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018
The substance use disorders Diseases of substance dependence (SAW) represent the «pharmacogenetic» diseases caused by abnormal and genetically determined response of the CNS to use of the substance of abuse (SA), conscious and regulated by person itself.
A. O. Kibitov
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Monitoring post-approval drug safety in pregnancy: pharmacogenetic aspects

Безопасность и риск фармакотерапии, 2018
The purpose of this article is to describe and to examine the utility of new pharmacogenetic approaches in monitoring post-approval drug safety in pregnancy. Data on gene expression in pregnancy and metabolic variation may, in specific instances, help to

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Evaluation of the effect of the carrier of polymorphic variants of the SLCO1B1 gene on efficacy and safety in patients during treatment with statins

Безопасность и риск фармакотерапии, 2018
The number of patients receiving statins is increasing every year. Considering the need for life-long intake of drugs of this group, the problem of improving safety and efficacy of their use becomes especially important.
N. A. Rumyantsev, Yu. V. Olefir, V. G. Kukes   +2 more
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Pharmacogenetics of antiepileptic drugs (literature review)

Качественная клиническая практика, 2018
The article presents modern concepts of genes, polymorphisms which can influence the pharmacological response of the patient receiving antiepileptic drugs.
E. . Bochanova
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