Results 41 to 50 of about 357 (82)
Клиническая фармакогенетика: тернистый путь внедрения в клиническую практику
Качественная клиническая практика, 2018 Один из путей повышения эффективности и безопасности лекарственных средств - персонализированная медицина.
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Зв'язок однонуклеотидного поліморфізму генів MGP і VDR з розвитком ішемічного атеротромботичного інсульту [PDF]
, 2013 Вперше встановлено, що алельний поліморфізм гена МGP є важливим чинником спадкової схильності до розвитку ІАТІ. У гомозигот за мінорним алелем A/A (G-7A поліморфізм) ризик ІАТІ у 2,6 раза більший , ніж у носіїв основного алеля (G/G+G/A).
Ataman, Oleksandr Vasylovych +26 more
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As a Carrier Protein of a Medicinal Product the Main Properties of Р-Glycoprotein [PDF]
, 2022 To predict the pharmacokinetic interaction of drugs during absorption, distribution and excretion, it is also necessary to know the potential of substances to affect the body's transport systems, including glycoprotein-P (Pgp) and change its functional ...
Saidovna, Ochilova Gulrukh
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Рациональная фармакотерапия в кардиологии, 2015 The clinical significance of the SLCO1B1 gene polymorphism (encoding an organic anion transport polipeptide) in the development of statin induced myopathy is considered.
D. A. Sychev +2 more
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Pharmacogenetic testing: current state of the issue [PDF]
Aim. The purpose of this work is to emphasize the importance and practical benefits of pharmacogenetics in medicine, demonstrating how the integration of pharmacogenetics into clinical practice can improve treatment outcomes and enhance the safety of ...
O. O. Kremzer +2 more
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Клиническая фармакология, фармакологическая терапия [PDF]
, 2010 ПОСОБИЯФАРМАЦИЯФАРМАКОЛОГИЯ КЛИНИЧЕСКАЯЛЕКАРСТВЕННАЯ ТЕРАПИЯПРАКТИЧЕСКИЕ ЗАНЯТИЯВ пособие входят темы лекций и практических занятий по клинической фармакологии с основами фармакотерапии, карта фармакологического анализа, перечень рекомендуемой ...
Конорев, М. Р. +8 more
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EVALUATION OF SENSITIVITY TO CLOPIDOGREL: THE CURRENT STATE OF THE PROBLEM
Атеротромбоз, 2015 The review deals with the laboratory assessment of clopidogrel effect in patients with CHD. The article presents the results of major studies that have demonstrated the relationship between the residual platelet reactivity level and drug pharmacogenetics
A. L. Komarov
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Рациональная фармакотерапия в кардиологии, 2015 The clinical significance of CYP2C19 genetic polymorphism, associated with the violation of the formation of the active clopidogrel metabolite, for efficacy and safety of this drug in cardiology practice is discussed.
K. B. Mirzaev +3 more
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PREVALENCE OF POLYMORPHOUS LOCUS 681G>A OF CYP2C19 GENE IN RUSSIAN POPULATION
Acta Biomedica Scientifica, 2014 The prevalence of genotypes and alleles of polymorphous locus 681G>A of CYP2C19 gene in Russian population of Eastern Siberia. We conducted comparative analysis of response characteristics with previous data of other world's populations.
T. A. Bairova +3 more
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Clinical and genetic characteristics of treatment-resistant asthma
Медицинский совет, 2013 Therapy resistant asthma (TRA) is most difficult to treat and its course is least predictable. TRA remains least studied despite the fact that its many mechanisms have been detected.
V. I. Trofimov, G. A. Mironova
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