Zhongguo shiyan zhenduanxue, 2019 目的了解黑龙江省佳木斯地区高尿酸血症(HUA)的患病率并分析其与其他代谢性疾病的相关性。方法选取1249例佳木斯大学附属第一医院2017年8月-2018年6月健康体检者,分为高尿酸血症组(HUA组,n=316)与非高尿酸血症组(NUA组n=933),进行统计学分析。结果1.HUA患病率为25.3%,男性明显高于女性(35.10%VS 13.7%);2.HUA组中各代谢性疾病的患病率均显著高于NUA组 ...
隋小芳 +4 more
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[Metabolomic changes of neonatal sepsis: an exploratory clinical study]. [PDF]
Zhongguo Dang Dai Er Ke Za Zhi, 2022 Tong P +9 more
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The correlation and metabolomics analysis of M. PCC 7806 cell aggregation and MrpC [PDF]
, 2017 蓝藻水华的形成可分为四个阶段：藻细胞休眠、复苏、生物量积累、聚集上浮。铜绿微囊藻（Microcystisaeruginosa）PCC7806是一种频繁引发水华的淡水蓝藻。在实验室中培养的藻细胞均匀分散，即使生物量积累到足够爆发水华的阶段，也未观察到藻细胞聚集成群落的现象。研究水华的形成机制，需要在实验室中先模拟蓝藻聚集。本实验室前期研究发现，铜绿微囊藻PCC7806分泌的MrpC蛋白，可在水体中形成网状纤维结构，具有抑制藻细胞下沉的功能。在藻细胞表面也附着有MrpC蛋白 ...
古莎
core
Non-targeted Metabolomics Analysis of Metabolite Differences amongst Different Parts of Physalis alkekengi L. var. franchetii [PDF]
Non-targeted metabolomics techniques were used to analyze the metabolite differences in the calyx, fruit, stem, and root of Physalis alkekengi L. var. franchetii (PAVF). The metabolomic profiles of PAVF were investigated by UHPLC-Q-Orbitrap HRMS with PCA,
Hao ZHANG +3 more
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[Development of a widely-targeted metabolomics method based on gas chromatography-mass spectrometry]. [PDF]
Se Pu, 2023 Wang YT, Yang Y, Sun XL, Ji J.
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Discrimination Analysis of Conventional Baijiu-making Sorghum from Southwest China and Hybrid Sorghum Based on Physicochemical Properties and Metabolomics [PDF]
The objective of this paper was to analyze the difference of composition between hybrid sorghum and conventional sorghum in southwest China, and to establish the method of variety identification.
Anjing CHEN +6 more
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Haiyang yu huzhao卤虫(Artemia)是生存在高盐水体中的小型甲壳动物，其能够耐受多种极端环境，并可在不同的栖息地展现出不同的生理适应性，然而目前对于不同海拔地区卤虫肠道微生物组成及其与卤虫环境适应机制了解甚少。采用16S rRNA高通量测序和代谢组学技术，首次对来自高海拔地区的拉果错卤虫(A. tibetiana)和低海拔地区的渤海湾卤虫(A. franscicana和A.
韩 学凯 +5 more
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[Pseudotargeted metabolomics analysis of pine pollen intervention in the liver of premature ovarian failure rats]. [PDF]
Se Pu, 2023 Qu T +8 more
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Toxicity Study of VOSO_4 Using NMR-based Metabonomics [PDF]
, 2010 通讯作者：陈忠 E-mail: chenz@xmu.edu.cn[中文文摘]采用基于核磁共振(NMR)的代谢组学方法,结合生化指标分析及组织病理学检测,研究了具有类胰岛素活性的硫酸氧钒(VOSO4)对Wistar大鼠的毒性作用.通过不同剂量的VOSO4对Wistar大鼠连续灌胃给药16d,收集大鼠的血清和尿液,并采集样品的1H NMR谱进行多变量数据统计分析来辨识其特征代谢物,然后采用TICL(a web Tool for automatic Interpretation of Compound ...
危阳洋 +4 more
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Zhongguo shiyan zhenduanxue, 2017 表观遗传学是研究在基因的核苷酸序列不发生改变的情况下,基因发生了可遗传的表达的一门新兴学科。其机制主要包括DNA甲基化,组蛋白修饰,代谢记忆,RNA介导的基因沉默,染色质重塑及基因组印记等。糖尿病是以高血糖及胰岛素缺乏为特征的一种多因素的慢性代谢性疾病,与基因及环境因素相关[1]。近几年,越来越多的研究表明 ...
燕艳, 刘仲祥, 张秀娟
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