Results 31 to 40 of about 9,333 (168)

Nutritional and Physiological Markers Are Mediated by Seasonality and Forest Access in Captive Coquerel's Sifakas 圈养科氏冕狐猴 (Coquerel's Sifakas) 的营养和生理指标受季节性和森林通道的影响

open access: yesIntegrative Conservation, Volume 4, Issue 4, Page 652-664, December 2025.
We profiled nutritional and physiological markers in captive sifakas, endangered primates from Madagascar, managed in expansive, non‐native forest enclosures. Variation in many markers reflects freely foraged diets and the energy required to maintain homeostasis under more naturalistic conditions.
Lydia K. Greene   +5 more
wiley   +1 more source

Applications of nuclear magnetic resonance spectroscopy and Raman spectroscopy in the studies of hepatic cancer and nasopharyngeal carcinoma [PDF]

open access: yes, 2016
癌症是全人类共同面临的健康问题。在我国东南沿海地区,肝细胞性肝癌(hepatocellularcarcinoma,HCC)和鼻咽癌(nasopharyngealcarcinoma,NPC)形势尤为紧迫。当前针对HCC和NPC的诊疗手段因受各种因素影响而作用十分有限。针对区域性重要恶性肿瘤疾病的实验研究和临床需求出发,本文利用核磁共振波谱、拉曼光谱和表面增强拉曼光谱等技术分别研究HCC和NPC的血液、细胞株以及亚细胞组分等生化样本的谱学特征,结合多种统计学方法从诊、疗两个层面探索相关的生物标记物 ...
陈阳
core  

Plant–microbe interactions drive the rhizosphere microbial assembly and nitrogen cycling in a subtropical forest

open access: yesFunctional Ecology, Volume 39, Issue 5, Page 1274-1287, May 2025.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Interactions between plants and soil microorganisms in the rhizosphere are vital for maintaining the nutrient cycle and stability of terrestrial ecosystems. Nitrogen, closely related to carbon (C) cycling and ecosystem productivity, undergoes transformation by soil ...
Ru Wang   +9 more
wiley   +1 more source

缺血性卒中的代谢组学应用研究及展望Application Research and Prospect of Metabolomics in Ischemic Stroke

open access: yesZhongguo cuzhong zazhi
代谢组学在缺血性卒中研究中具有重要应用价值,本文综述了代谢组学方法在揭示缺血性卒中的发病机制、预测发病风险、辅助临床诊断、优化治疗策略及评估预后等方面的应用进展。研究表明:代谢组学能够揭示缺血性卒中发生发展中的多种代谢异常,为发掘病理机制提供线索;通过识别代谢生物标志物,能有效预测发病风险并为早期诊断提供支持;结合人工智能方法可构建早期诊断模型,有助于区分卒中亚型,明确不同类型卒中的代谢差异,提高诊断准确性;通过监测卒中后治疗与功能恢复过程中的代谢物变化,可揭示新的潜在治疗靶点。展望未来 ...
唐奕欣1,涂汝欣1,夏健1,2 (TANG Yixin1, TU Ruxin1, XIA Jian1,2 )
doaj   +1 more source

Components Analysis and Classification of Beer and White Spirit Based on NMR Approach [PDF]

open access: yes, 2016
食品是人类生活中一类重要的必需品,各种食品具有不同的特性和成分,直接关系人体的健康。近年来,我国食品安全问题受到社会公众群体的广泛关注。核磁共振(NMR)技术相比于其他传统的检测方法,具有对样品的制备要求低、预处理简单,无损检测和高灵敏度等特点,在食品科学研究中得到广泛应用。 酒精类饮料属液态食品,啤酒更是继水、茶之后世界第三大饮用品,白酒则是中国特有酒种。目前基于NMR技术对啤酒的研究多停留在定性分析,化学成分的描述一般只针对某类化合物,对总体化学成分的全面研究较少。而基于NMR的白酒研究集中在国内 ...
栾晓菲
core  

Gut microbiota dynamics of adult and sub‐adult sika deer during reintroduction 重引入过程中成年和亚成年梅花鹿肠道微生物的动态变化

open access: yesIntegrative Conservation, Volume 3, Issue 3, Page 257-270, September 2024.
Natural training enclosure design schematic. We selected 12 sika deer including six adults and six sub‐adults. Key considerations in the design of the natural training were to divide the training spatial ground into two parts (30 × 30 m small areas for isolation of new individuals and large areas measuring 200 × 600 m for free walking), and the ...
Wentao Zhang   +10 more
wiley   +1 more source

代谢组学的研究进展及其在肾病综合征中的应用前景

open access: yesZhongguo shiyan zhenduanxue, 2013
系列"组学"技术的发展推动了基础研究水平的提高和深入。代谢组学作为一门新兴学科,着重研究的是生物整体、器官或组织的内源性代谢物质的代谢途径及其所受内在或外在因素影响下代谢整体的变化轨迹来反映某种病理生物过程。目前,代谢组学已广泛应用于生物学和医学相关的很多领域,在肝脏、心脏、肿瘤、肾脏等疾病中也有较深入的研究。本文就代谢组学的研究进展进行综述 ...
陆荣华, 杜玉君
doaj  

Research of diagnostic biomarkers in Breast cancer and Gastric cancer [PDF]

open access: yes, 2013
自生物标志物(biomarker)这一概念提出以来,肿瘤生物标志物(tumorbiomarker,TBM)在基础医学领域的研究已成为热点。本文基于大量的临床病理样本,利用免疫组织化学、甲基化芯片分析、实时荧光定量PCR等技术,研究乳腺癌、胃癌预后诊断的生物标志物,为疾病的治疗提供新的思路和靶点。 我们利用免疫组织化学,调查了酪氨酸磷酸酶Shp2和它的伴侣蛋白Gab2在141例乳腺浸润性导管癌中的表达,并分析了他们与临床病理学特征的相关性,发现Gab2蛋白表达与病人的年龄存在显著相关性 ...
陈宝珍
core  

室内植物表型平台及性状鉴定研究进展和展望 [PDF]

open access: yes, 2020
Plant phenomics is under rapid development in recent years, a research field that is progressing towards integration, scalability, multi-perceptivity and high-throughput analysis.
Guohui, Ding   +6 more
core   +1 more source

代谢性脑血管病:概念、方法、挑战和未来方向 Cerebro-Metabolic Disease: Concept, Method, Challenge and Future Directions

open access: yesZhongguo cuzhong zazhi, 2023
代谢危险因素是导致心脑血管病的重要原因。目前代谢性心血管病已有明确的概念和综合管理体系,而在我国发病率高、异质性强的脑血管病领域,尚未形成统一的代谢性脑血管病的定义和概念。本文综述脑血管病的代谢危险因素,提出代谢性脑血管病的概念和分类,阐述基于多组学技术的多学科、多器官水平的研究方法,介绍近年来涌现的具有心血管获益的代谢药物的特点及未来面临的挑战和研究方向,为代谢性脑血管病的综合管理提供理论依据。 Abstract: Metabolic risk factors are important ...
许杰,王拥军
doaj   +1 more source

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