Results 21 to 30 of about 12,711 (166)

Self‐Consumption Translation: Exploring Interlingual Translation Within Multilingual (mainland) China

open access: yesInternational Journal of Applied Linguistics, Volume 36, Issue 1, Page 714-724, February 2026.
ABSTRACT Interlingual translation, as defined by Roman Jakobson, refers to the transfer of meaning between languages. However, this concept has often been conflated with linguistic shifts between distinct cultures and nation‐states. To challenge this misconception, I propose the concept of self‐consumption translation (SCT), a subfield of interlingual ...
Bilin (Belen) Liu
wiley   +1 more source

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

open access: yesDevelopmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua   +6 more
wiley   +1 more source

SWEET1‐mediated glucose transport is crucial for energy availability in Arabidopsis

open access: yesNew Phytologist, Volume 249, Issue 4, Page 1816-1830, February 2026.
Summary The stress‐responsive hormone abscisic acid (ABA) is known for its inhibitory effects on various physiological processes, including seed germination, often resulting in energy deprivation. Interestingly, ABA‐induced germination inhibition can be alleviated by exogenous glucose (Glc), mimicking a functional interplay between ABA and sugar ...
Xueyi Xue   +3 more
wiley   +1 more source

CHINA’S LAND FINANCE AS ACTIVE MODE OF LAND DEVELOPMENT AND INFRASTRUCTURE DELIVERY: Reality, History and Prospects

open access: yesInternational Journal of Urban and Regional Research, Volume 50, Issue 1, Page 191-220, January 2026.
Abstract Henry George advocated for capturing land value increases for public ends. The active approach of public authorities organizing and financing land development can help capture higher land value increases, as Hartman and Spit indicate. However, this approach hardly happens in developing countries, where the coalition of private developers and ...
Nannan Xu
wiley   +1 more source

Transcriptomic profiling of dorsal root ganglia in atopic and healthy dogs: A comparative RNA sequencing study with implications in cutaneous itch research

open access: yesVeterinary Dermatology, Volume 36, Issue 4, Page 401-411, August 2025.
Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Chie Tamamoto‐Mochizuki   +1 more
wiley   +1 more source

How Many Floods Have Occurred in China in the Past Decade? A Perspective From Social Media

open access: yesEarth's Future, Volume 13, Issue 4, April 2025.
Abstract Global climate change has led to frequent and widespread flood disasters in China. Traditional flood disaster investigations mainly focus on major flood events, and small‐scale flood events are often overlooked. This study utilized the Sina Weibo social media platform to detect flood events in 370 cities in China from 2012 to 2023.
D. Shen   +5 more
wiley   +1 more source

Yap Regulates ATF6-Mediated Unfolded Protein Response [PDF]

open access: yes, 2015
Hippo信号通路最早在果蝇里发现,是在进化上高度保守的一条激酶级联的通路,当Hippo通路的缺失会造其下游调控因子Yap或Taz的激活,促进细胞增殖,抑制细胞凋亡,从而导致器官增大和肿瘤产生。此外,大量文献阐述了内质网压力和肿瘤产生具有相关性。本实验室研究表明,Hippo通路的缺失或Yap蛋白的激活会引起内质网应激信号通路的激活和内质网的增大,并通过内质网应激反应导致肝脏器官增大和肿瘤生成。 当Hippo激酶,在高等动物的同源物为Mst1和Mst2激酶的缺失或Yap激活时 ...
蔡亚波
core  

jck多囊肾小鼠肾囊泡上皮细胞MAPK信号通路上调

open access: yesZhongguo shiyan zhenduanxue, 2012
目的通过研究MAPK信号通路在多囊肾囊泡上皮细胞的调控,探讨多囊肾病的发病机制。方法以常染色体隐性遗传病jck多囊肾小鼠为模型,采用Western印迹法评价MAPK信号通路在jck多囊肾小鼠肾脏的表达和磷酸化调控。结果 jck多囊肾小鼠肾囊泡上皮细胞MAPK信号通路蛋白H-Ras、p-Raf、p-MEK、pERK、c-fos水平上调。结论 MAPK信号通路参与jck多囊肾小鼠肾囊泡的发生发展,提示MAPK通路可作为治疗多囊肾病的药物靶点。
阚秀芳   +6 more
doaj  

Role of E3 ubiquitin ligase Smurf1 in regulating NF-κB Signaling [PDF]

open access: yes, 2016
核因子NF-kappaB是一种在哺乳动物体内广泛表达并且种属间高度保守的转录因子,它在免疫及炎症反应、生长发育、肿瘤形成等多个生理及病理学过程中发挥关键的调控作用。静息状况下,NF-kappaB与NF-kappaB抑制因子IkappaBalpha(InhibitorofNF-kappaB,IkappaBalpha)在胞质中形成复合物,其功能活性被抑制。但当细胞受到上游配体(例如肿瘤坏死因子alpha(tumornecrosisfactoralpha,TNFalpha)的刺激之后 ...
王群
core  

JAK/STAT3信号通路参与白细胞介素-17诱导的支气管平滑肌细胞增殖与迁移

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2019
【目的】探讨白介素-17(IL-17)促进支气管平滑肌细胞(BSMC)的增殖与迁移作用及JAK/STAT3相关信号通路在其中的作用机制。【方法】使用不同浓度IL-17处理BSMC不同时间,以确定最佳实验条件。随后使用MTT检测细胞活力,BrdU染色观察细胞增殖状态,并使用PI染色流式细胞仪检测细胞周期。进一步利用细胞迁移实验检测细胞迁移能力。使用Westernblot实验检测IL-17处理后BSMC的JAK、p-JAK、STAT3、p-STAT3蛋白表达量。利用JAK ...
蓝引乐, 朱妤, 王建华, 凌元亮
doaj  

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