Results 11 to 20 of about 13,923 (166)
The Anatomical Record, Volume 306, Issue 12, Page 3214-3228, December 2023., 2023 Abstract The effectiveness and safety of electroacupuncture (EA) for constipation have been confirmed by numerous clinical studies and experiments, and there are also studies on the efficacy of EA for Parkinson's disease (PD) motor symptoms. However, there are few researches on EA for PD constipation.
Li‐Zhe‐Xiong Song +8 more
wiley +1 more source
The latest progress of breast cancer treatment at 2023 ESMO [PDF]
, 2023 At 2023 Annual Meeting of European Society of Medical Oncology (ESMO), Several latest research achievements in the field of breast cancer were announced.
ZHOU Teng, ZHANG Jian
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Research progress of MDSCs-targeted immunotherapy for pancreatic cancer [PDF]
, 2023 Pancreatic cancer (PC) is a highly malignant digestive system tumor with a poor survival rate and prognosis. Most patients with pancreatic cancer have no obvious clinical manifestations in the early stage of the disease, and are found to be in the middle
PENG Meiyu +4 more
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Advancements in the research of immunomodulatory effects of radiation therapy: from basic to clinical [PDF]
, 2023 Previously, radiotherapy was considered to directly kill tumor cells by deoxyribonucleic acid double-strand break. Recent studies have found that radiotherapy can also produce positive and effective anti-tumor effect by upregulating local and systemic ...
WANG Yu, BI Nan
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Current status and treatment direction of the immune microenvironment of castration-resistant prostate cancer [PDF]
, 2023 With the rapid development of cancer immunology, more and more research focuses on the role of immune cells and signaling molecules in the tumor microenvironment. Prostate cancer is the second most common malignant tumor in men globally.
YANG Wenbo, ZHANG Bin, WU Jiahui, CUI Jie
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Veterinary Dermatology, Volume 37, Issue 2, Page 306-318, April 2026.Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova +6 more
wiley +1 more source
The Expression and Biological Significance of PD-L1 on Lung Cancer Cell Lines [PDF]
, 2009 Background and objective Tumor-associated PD-L1 expression was recently shown to promote T-cell apoptosis and proposed as a potential mechanism of immune evasion by tumors. On the basis of the ability of tumor-associated PD-L1 to mediate activated T-cell
Cheng CHEN +6 more
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Rare Metals, Volume 45, Issue 3, March 2026.ABSTRACT Lung cancer remains the leading cause of cancer‐related deaths worldwide, yet immune checkpoint blockade (ICB) is often compromised by an immunosuppressive tumor microenvironment (TME) with acidosis, hypoxia, and poor T cell infiltration. Here, we develop a TME‐responsive nanoplatform (MgH2@Lip/PD‐L1) that couples hydrogen gas therapy with PD ...
Xuyu Gu +5 more
wiley +1 more source
Construction of CpG-Au@HBc virus like particles and study of their membrane translocation mechanism, immunostimulary effect [PDF]
, 2016 乙肝病毒核心蛋白病毒样颗粒（HepatitisvirusBviruscoreproteinviruslikeparticles，HBcVLPs）因其不具有乙肝病毒的复制能力而又具备较强的免疫原性而被广泛应用于构建新型疫苗。另一方面，HBcVLPs的正二十面体空腔结构和解聚/自组装特性使得其还能够作为纳米载体呈递基因、纳米粒子等。本课题利用HBcVLPsC末端的富集正电荷序列可以通过静电吸引力与核酸相互作用的特点，构建了一种同时包裹有CpG寡核苷酸链（CpGODNs）佐剂和金纳米粒子的HBcVLPs ...
王雅润
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Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang +7 more
wiley +1 more source