Results 11 to 20 of about 31,733 (245)

Injectable Biomimetic Composite Hydrogel Scaffold With Tissue‐Engineered Cartilage Matrix for Articular Cartilage Regeneration

open access: yesRare Metals, EarlyView.
ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu   +13 more
wiley   +1 more source

Fabricating Highly Efficient Ternary Mn–CeOx/Co3O4 Catalysts for Low Temperature Thermal Desorption of Persistent Perfluorooctanoic Acid in Soil

open access: yesRare Metals, EarlyView.
ABSTRACT Developing efficient catalytic thermal desorption systems is of great significance in the field of sustainable soil remediation. Herein, novel Mn–Ce solid solution modified Co3O4 nanocrystals were successfully prepared for the removal of perfluorooctanoic acid (PFOA) in soil.
Yu‐Hao Liu   +8 more
wiley   +1 more source

Endogenous/Exogenous Dual‐Responsive Bimetallic Hollow Nanozyme for Photothermal/Nanocatalysis/Immune Synergistic Tumor Therapy

open access: yesRare Metals, EarlyView.
ABSTRACT Nanozymes have attracted considerable attention in cancer therapy due to their adjustable enzyme activity and high catalytic efficiency. However, they still face a major challenge from tumor metastasis. In this work, endogenous/exogenous dual‐responsive bimetallic hollow PdRu (termed HPdRu) nanozymes were prepared.
Nan‐Nan Zheng, Xin Hu, Jun‐Qing Hu
wiley   +1 more source

Boron Difluoride Chelated Aminoanthraquinone Photosensitizer for Type I Photodynamic Therapy

open access: yesRare Metals, EarlyView.
ABSTRACT Type I photosensitizers capable of generating cytotoxic reactive oxygen species (ROS), with reduced oxygen dependence under photoirradiation, are regarded as a promising phototherapeutic approach for hypoxic solid tumors. Herein, based on the electron donor of 9‐phenyl‐carbazole (Cz) and the electron acceptor of anthraquinone (AQ ...
Tian Zhang   +8 more
wiley   +1 more source

Realizing the Enhanced Electromagnetic Wave Absorption and Self‐Cleaning Pollution in BaFe12O19 Composite

open access: yesRare Metals, EarlyView.
ABSTRACT With increasing complex requirement in organic pollution environment, the development of actual electromagnetic wave (EMW) absorbers with high EMW absorption performance and self‐cleaning pollution function is becoming a significant challenge.
Shou‐Hang Lv   +8 more
wiley   +1 more source

邯郸市乙型肝炎基因分型及其临床意义研究

open access: yesZhongguo shiyan zhenduanxue, 2010
目的研究不同类型乙型肝炎病毒(HBV)感染者中HBV基因型分布情况及其临床意义。方法应用基因型特异性引物聚合酶链反应法(PCR),对180份HBV感染者血清进行基因型分型。结果180份标本中,162份(90%)可检出基因型,18份(10%)未检出基因型。162份HBV基因型分布为:B基因型1例(0.6%),C基因型159例(98.1%),B+C混合基因型2例(1.2%),未检出A、D、E、F基因型。结论邯郸地区HBV感染者中,基因型分布较单一,C基因型占绝对优势,同时存在少量B基因型及B+C混合基因型 ...
邓健   +6 more
doaj  

The effect of PNPLA3 ploymorphism in the intervention of non-alcoholic fatty liver disease [PDF]

open access: yes, 2015
研究目的 运动是治疗非酒精性脂肪性肝疾病的一个重要方法,而脂肪滋养蛋白基因(PNPLA3)是非酒精性脂肪性肝疾病的一个重要的基因遗传因子。本研究的目的是为了探讨脂肪滋养蛋白基因的多态性表达是否影响到运动干预非酒精性脂肪性肝疾病的过程。 研究方法 本研究共招募40-65岁中心性肥胖受试者1059人,进行常规体检,并运用彩超检测脂肪肝。并随机抽取476名肥胖受试者进行1H-MRS对其肝内甘油三酯进行定量测定。在这476名肥胖受试者中,随机抽取220人分为三组,强化运动组(先进行6个月的强化运动期 ...
黄竹锋
core  

A Mini Review on Evolution of High‐Entropy Alloy Design: From Experimental Approaches to Machine Learning Integration

open access: yesRare Metals, EarlyView.
ABSTRACT High‐entropy alloys (HEAs) have emerged as a transformative class of materials distinguished by their complex chemical compositions, unique microstructures, and remarkable mechanical and functional properties. Traditionally, the discovery and optimization of HEAs have relied on conventional methods, including trial‐and‐error experimentation ...
Chrispin Ouko Zamzu   +2 more
wiley   +1 more source

AS-PCR法检测CLU基因SNP位点方法的建立

open access: yesZhongguo shiyan zhenduanxue, 2019
目的基于等位基因特异性PCR(allele-specific PCR,AS-PCR)原理,建立一种QPCR检测CLU基因与阿尔兹海默病(AD)相关性SNP位点基因型的筛选方法。方法根据CLU基因上的rs11136000,rs2279590和rs9331888 3个SNP位点设计特异性的野生型、突变型引物,使用实时荧光定量PCR(QPCR)对AD患者外周血样本进行SNP基因分型,以DNA基因测序法结果作为参考标准。结果 10例样本的QPCR定量分型结果显示 ...
李逸豪   +8 more
doaj  

The Study of Ultrastructure、ATP、Calcium and RNA-Seq in fertile and sterile anthers of Lycium Barbarum L. [PDF]

open access: yes, 2016
高等植物的雄性不育是杂种优势利用的基础,避免了去雄的繁杂程序。植物雄性不育的种类很多,形成原因也很复杂,对雄性不育机理的探索一直是一个热门研究领域。枸杞雄性不育系是近年来新发现的一种不育类型,具有很大应用潜力,为了明确其雄性不育发生的机制并更好地开发利用这一宝贵种质资源,我们从结构、生理和分子生物学等几个方面展开了研究。 本研究以可育系宁杞1号和不育系宁杞5号为实验材料,用超微结构、ATPase和Ca2+的细胞化学定位,以及转录组和数字基因表达谱研究了枸杞花药发育的特征并比较了不育花药形态 ...
杨淑娟
core  

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