Results 31 to 40 of about 34,083 (145)
目的探讨苏北地区慢性乙型肝炎(慢乙肝)患者乙型肝炎病毒(HBV)基因型分布情况及基因型与性别、年龄、疾病分类、HBV-P基因YMDD(YMDD)变异的相关性。方法血清HBV基因型及YMDD变异检测均采用PCR-微板杂交-ELISA法。结果130例患者中基因型B(B型)占3.1%(4/130),基因型C(C型)占50.0%(65/130),基因型非B非C型(NBNC型)占46.9%(61/130)。男、女两组基因型差异未见统计学意义(χ2=1.338,P>0.05)。4例B型均为40岁以下的慢乙肝患者 ...
赵绍林 +4 more
doaj
Topics as Outcomes: Modeling the Influence of Intergovernmental Grants on Policy Diffusion
ABSTRACT Intergovernmental grants stimulate the diffusion of policy reforms, as the federal government provides states with a financial incentive to adopt policies aligned with federal priorities. Less is known about the extent to which these grants also stimulate horizontal diffusion across states.
NaLette Brodnax, Sarah James
wiley +1 more source
目的探讨白细胞介素-17F基因多态性与儿童支气管哮喘的相关性,为支气管哮喘的易感基因筛选提供可能的理论依据。方法取本院门诊随诊的60例哮喘患儿设为哮喘组,60例健康儿童设为对照组,两组儿童均于清晨空腹留取外周静脉血2ml,提取全基因组DNA,应用聚合酶链反应及克隆、基因测序方法分析IL-17F基因序列rs763780(H161R)基因多态性。结果 IL-17F基因序列rs763780(H161R)基因型在两组内均未检测到突变型CC,rs763780(H161R)基因型(TC/TT ...
赵宏霞, 刘瑜, 庄哈娜
doaj
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon +5 more
wiley +1 more source
ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis
ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake +2 more
wiley +1 more source
目的研究天津地区丙型肝炎病毒(HCV)基因型的分布。方法收集HCV感染者的HCV基因分型、性别、年龄、临床诊断等临床资料,分析HCV基因型在人群中的分布,以及与临床资料的相关性。结果天津地区最常见的HCV基因型是1b型,占人群比例77.88%;其次是2a型,占人群比例20.07%。在肝炎患者,不同基因型感染者的平均年龄之间存在差异。在肝硬化患者,不同性别的HCV基因型分布存在差异。结论天津地区HCV基因型以1b型最为常见。
武玉晶 +4 more
doaj
Spatially Downscaling of Future Food Demand for Policy Planning
ABSTRACT Understanding the subnational dynamics of food demand, while accounting for the evolution of the agrifood system at the global level, remains a challenge for designing food policy to ensure food security. To link global agrifood systems with subnational food policy planning, we downscale per capita food demand for 62 food commodities at the ...
Chun Song +3 more
wiley +1 more source
目的探讨血管紧张素原基因(AGT)T174在人群中的分布、与临床心肌梗死的相关性。方法对入选的心肌梗死患者组及健康对照组,用聚合酶链反应(PCR)、限制性片段长度多态性(RFLP)分析,对群体患者和群体健康对照组进行基因分型,统计分析。结果 AGT基因型频率及等位基因频率分布比较均匀;心肌梗死发生与民族、性别、年龄无特异相关性。174MM型和M 174等位基因的频率患者组显著高于健康对照组,携带突变型MM基因型的个体比野生型TT者患心肌梗死的危险性高5.667倍,基因突变与心肌梗死发生相关。结论 ...
宁树成 +3 more
doaj
ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou +8 more
wiley +1 more source

