Results 11 to 20 of about 15,062 (116)

Diagnostic yield using whole‐genome sequencing and in‐silico panel of 281 genes associated with non‐immune hydrops fetalis in clinical setting

Ultrasound in Obstetrics &Gynecology, Volume 60, Issue 4, Page 487-493, October 2022., 2022
ABSTRACT Objective To investigate the diagnostic yield of clinical whole‐genome sequencing (WGS) in prenatally diagnosed non‐immune hydrops fetalis (NIHF). Methods This was a retrospective study of 23 fetuses with prenatally diagnosed NIHF, negative for trisomies and copy‐number variants, referred for analysis by WGS with an in‐silico panel of 281 ...
E. Westenius, E. Sahlin, P. Conner, A. Lindstrand, E. Iwarsson   +4 more
wiley   +1 more source

Effects of SGLT2 inhibitors on patients with diabetic kidney disease: A preliminary study on the basis of podocyturia SGLT2抑制剂对糖尿病肾病患者的影响:基于尿足细胞的初步研究

Journal of Diabetes, Volume 14, Issue 4, Page 236-246, April 2022., 2022
Highlights Diabetic kidney disease is a progressive disease with the pathology of glomerular damage and loss of podocytes. Sodium glucose cotransporter 2 inhibitors (SGLT2i) can be expected to decrease the amount of podocyte excretion. Male patients receiving SGLT2i have better diabetic kidney disease‐related parameters and podocyturia levels. Abstract
Emre Durcan, Serbay Ozkan, Halil Ibrahim Saygi, Mevlut Tamer Dincer, Ozge Polat Korkmaz, Serdar Sahin, Cebrail Karaca, Cem Sulu, Alev Bakir, Hande Mefkure Ozkaya, Sinan Trabulus, Elif Guzel, Nurhan Seyahi, Mustafa Sait Gonen   +13 more
wiley   +1 more source

Cutaneous microRNA expression in healthy Labrador and Golden retrievers and retrievers with allergic and inflammatory skin diseases

Veterinary Dermatology, Volume 32, Issue 4, Page 331-e92, August 2021., 2021
Background MicroRNAs (miRNA) are short, single‐stranded RNA molecules that regulate gene expression in a post‐transcriptional manner. Their expression is proposed to be tissue‐specific and alterations in miRNA expression have been detected in many diseases. Objective To compare miRNA expression in the skin of healthy Labrador and golden retrievers, and
Marie Isabel Morlang, Karin Weber, Wolf von Bomhard, Ralf S. Mueller   +3 more
wiley   +1 more source

Faecalibacterium prausnitzii‐derived microbial anti‐inflammatory molecule regulates intestinal integrity in diabetes mellitus mice via modulating tight junction protein expression 普拉梭菌活性产物‐微生物抗炎分子通过调控细胞紧密连接蛋白表达修复糖尿病小鼠肠道屏障

Journal of Diabetes, Volume 12, Issue 3, Page 224-236, March 2020., 2020
Highlights Diabetic conditions induce compositional dysbiosis of the gut microbiota and impair gut barrier integrity. Diabetic conditions markedly downregulate the abundance of Faecalibacterium prausnitzii in the gut. Under diabetic conditions, microbial anti‐inflammatory molecules from Faecalibacterium prausnitzii restore the gut barrier and ZO‐1 ...
Jihao Xu, Rongrong Liang, Wang Zhang, Kuangyi Tian, Jieyao Li, Xianming Chen, Tao Yu, Qikui Chen   +7 more
wiley   +1 more source

RNAi沉默原代星形胶质细胞IL-17基因表达方法的建立

Zhongguo shiyan zhenduanxue, 2023
目的 通过基因沉默技术构建质粒成功转染原代星形胶质细胞(Ast)抑制IL-17表达，探讨IL-17的功能。方法 在制备原代Ast基础上，应用IL-17基因沉默质粒pGenesil-1A和B,用Lipofectamine 2000转染Ast,通过荧光分析法、RT-PCR法、Western Blotting法观察IL-17基因沉默后效果。结果 携带pGenesil-1B和A的IL-17基因沉默质粒制备成功后，免疫荧光携带pGenesil-1B转染效果明显高于pGenesil-1A,其转染率可高达56.72%;
沈笑然, 朱瑞锋, 郭佳翔, 李凌舟, 郭洪亮   +4 more
doaj  

Titanium Implant Abutments With Polydopamine‐Mesoporous Cerium Dioxide Coatings for Enhanced Antibacterial, Anti‐Inflammatory, and Soft Tissue Integration Properties

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT The poor soft tissue integration around titanium implants creates a microgap that serves as a pathway for pathogen invasion, resulting in infection, inflammation, and the progression of peri‐implantitis. As the implant’s transmucosal component, the abutment determines the degree of peri‐implant soft tissue attachment.
Xuan Li, Min Xing, Haoyue Liu, Kuicai Ye, Xuanyong Liu, Li Ma, Wenhao Qian, Jiajun Qiu   +7 more
wiley   +1 more source

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

Developmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会（the European Academy of Childhood Disability，EACD）牵头制定，旨在解决发育性协调障碍（developmental coordination disorder，DCD）的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题，通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础，以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类，最终转化为指南建议。并由国际 ...
Jing Hua, Wenchong Du, Xiaotian Dai, Meiqin Wu, Xianying Cai, Min Shen, Liping Zhu   +6 more
wiley   +1 more source

Progress and Prospects of Rare Metal‐Based Electrochemiluminescence Sensors for Detection of Water Environmental Pollutants

Rare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Water pollution is becoming increasingly severe, posing a serious hazard to human health and ecological security. Therefore, it is necessary to develop rapid, sensitive, and universal analytical methods to detect residual pollutants in actual water.
Yi Xing, Ru Wu, Min Zhang, Faliang Cheng, Jun‐Jie Zhu   +4 more
wiley   +1 more source

Developing HMME‐Conjugated NIR‐II Activated Carbon Dots Nanospray for the Treatment of MRSA Biofilm Infections in Diabetic Wound via PTT/CDT/SDT

Rare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou, Ning Wang, Zumeng Wang, Pingping Zhang, Yuqin Chu, Yingguang Liu, Wen Liu, Chengwu Zhang, Lili Yan   +8 more
wiley   +1 more source

Surface Sulfate Modification Promoted Excitons Extraction of BiOBr Nanosheets for Efficient 1O2 Photosynthesis and Chlorophenols Dechlorination

Rare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Photocatalytic molecular oxygen (O2) activation provides a sustainable approach to produce singlet oxygen (1O2) for organic contaminants detoxification. However, the charge carriers‐involved pathway usually suffers from unsatisfactory 1O2 production efficiency owing to energy loss caused by photogenerated hole‐mediated superoxide species (•O2−
Yan‐Biao Shi, Zhi‐Ping Yang, Chen‐Chen Zhang, Pin‐Ji Chen, Hao‐Yang Fu, Xu‐Peng Liu, Hao Li, Bo Lai, Li‐Zhi Zhang   +8 more
wiley   +1 more source