Results 21 to 30 of about 1,001,938 (172)

Faecalibacterium prausnitzii‐derived microbial anti‐inflammatory molecule regulates intestinal integrity in diabetes mellitus mice via modulating tight junction protein expression 普拉梭菌活性产物‐微生物抗炎分子通过调控细胞紧密连接蛋白表达修复糖尿病小鼠肠道屏障

Journal of Diabetes, Volume 12, Issue 3, Page 224-236, March 2020., 2020
Highlights Diabetic conditions induce compositional dysbiosis of the gut microbiota and impair gut barrier integrity. Diabetic conditions markedly downregulate the abundance of Faecalibacterium prausnitzii in the gut. Under diabetic conditions, microbial anti‐inflammatory molecules from Faecalibacterium prausnitzii restore the gut barrier and ZO‐1 ...
Jihao Xu, Rongrong Liang, Wang Zhang, Kuangyi Tian, Jieyao Li, Xianming Chen, Tao Yu, Qikui Chen   +7 more
wiley   +1 more source

RNAi沉默原代星形胶质细胞IL-17基因表达方法的建立

Zhongguo shiyan zhenduanxue, 2023
目的 通过基因沉默技术构建质粒成功转染原代星形胶质细胞(Ast)抑制IL-17表达，探讨IL-17的功能。方法 在制备原代Ast基础上，应用IL-17基因沉默质粒pGenesil-1A和B,用Lipofectamine 2000转染Ast,通过荧光分析法、RT-PCR法、Western Blotting法观察IL-17基因沉默后效果。结果 携带pGenesil-1B和A的IL-17基因沉默质粒制备成功后，免疫荧光携带pGenesil-1B转染效果明显高于pGenesil-1A,其转染率可高达56.72%;
沈笑然, 朱瑞锋, 郭佳翔, 李凌舟, 郭洪亮   +4 more
doaj  

From Tetracycline to Sulfamethoxazole: Photocatalytic Degradation and Mechanistic Insights in Aquatic Environments

Rare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT The pollution caused by antibiotics to aquatic ecosystems is becoming increasingly serious, thus more effective treatment methods are urgently required. Although the photocatalytic degradation behavior of tetracycline (TC) is relatively well understood, sulfamethoxazole (SMZ), an emerging pollutant originating from large‐scale livestock ...
Yihang Yang, Yiyi Zhang, Fang Yang, Xiaobing Wang, Yang Guo, Lin Sun, Shijie Li   +6 more
wiley   +1 more source

High‐Entropy Alloys for Photocatalysis: From Cocatalyst Engineering to Multifunctional Active Platforms

Rare Metals, Volume 45, Issue 9, September 2026.
ABSTRACT Photocatalysis has emerged as a promising approach for solar energy conversion and environmental remediation. However, its practical implementation is still hindered by limited charge‐separation efficiency, slow surface reaction kinetics, and insufficient catalyst stability.
Mengting Zhang, Guozhi Ma, Lin Wang, Yang Yang, Weiyou Yang, Huilin Hou   +5 more
wiley   +1 more source

3D Printed High‐Strength Hydrogel for Dual Release of Cu2+ and Ag+ Ions to Enhance Bone Repair and Antibacterial Properties

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Bone restoration is often hindered by the spatiotemporal dysregulation of immune and regenerative signals. Conventional bio‐inert implants, providing only passive support, fail to modulate this microenvironment, leading to infections and poor healing.
Zhizhong Sun, Yifei Wang, Yi Zheng, Minying Li, Longbao Feng, Ziwei Jiang, Hengrui Liu, Rui Guo, Weipeng Sun   +8 more
wiley   +1 more source

Titanium Implant Abutments With Polydopamine‐Mesoporous Cerium Dioxide Coatings for Enhanced Antibacterial, Anti‐Inflammatory, and Soft Tissue Integration Properties

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT The poor soft tissue integration around titanium implants creates a microgap that serves as a pathway for pathogen invasion, resulting in infection, inflammation, and the progression of peri‐implantitis. As the implant’s transmucosal component, the abutment determines the degree of peri‐implant soft tissue attachment.
Xuan Li, Min Xing, Haoyue Liu, Kuicai Ye, Xuanyong Liu, Li Ma, Wenhao Qian, Jiajun Qiu   +7 more
wiley   +1 more source

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

Developmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会（the European Academy of Childhood Disability，EACD）牵头制定，旨在解决发育性协调障碍（developmental coordination disorder，DCD）的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题，通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础，以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类，最终转化为指南建议。并由国际 ...
Jing Hua, Wenchong Du, Xiaotian Dai, Meiqin Wu, Xianying Cai, Min Shen, Liping Zhu   +6 more
wiley   +1 more source

Progress and Prospects of Rare Metal‐Based Electrochemiluminescence Sensors for Detection of Water Environmental Pollutants

Rare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Water pollution is becoming increasingly severe, posing a serious hazard to human health and ecological security. Therefore, it is necessary to develop rapid, sensitive, and universal analytical methods to detect residual pollutants in actual water.
Yi Xing, Ru Wu, Min Zhang, Faliang Cheng, Jun‐Jie Zhu   +4 more
wiley   +1 more source

Klotho基因转染促进脂肪间充质干细胞增殖的实验研究

Zhongguo shiyan zhenduanxue, 2012
目的探讨klotho基因转染对脂肪间充质干细胞（ADSCs）增殖的影响。方法将含有klotho全长基因的真核质粒转染至从脂肪组织分离的ADSCs中,采用CCK-8法测定转染后细胞增殖率,western blot法检测转染后细胞周期蛋白D1的表达变化,流式细胞术检测转染前后ADSCs的细胞周期变化。结果转染klotho基因96h后AD-SCs的细胞增殖率为170.50%;流式细胞术检测结果显示,ADSCs转染klotho基因S期和G2期细胞明显增多;west-ern ...
韩冬, 徐煌, 郑永霞, 肖燕萍
doaj  

Developing HMME‐Conjugated NIR‐II Activated Carbon Dots Nanospray for the Treatment of MRSA Biofilm Infections in Diabetic Wound via PTT/CDT/SDT

Rare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou, Ning Wang, Zumeng Wang, Pingping Zhang, Yuqin Chu, Yingguang Liu, Wen Liu, Chengwu Zhang, Lili Yan   +8 more
wiley   +1 more source