Results 101 to 110 of about 68,002 (248)
ABSTRACT The Schottky barrier height (SBH), which serves as a pivotal determinant of charge carrier injection efficiency in electronic devices, critically governs electrical behavior at metal/semiconductor interfaces. However, pronounced metal‐induced gap states at metal contact interfaces induce Fermi‐level pinning, which constrains the ...
Xiaofei Liu +10 more
wiley +1 more source
目的利用基因芯片筛选与精子发生相关的基因,并研究其表达特征。方法将4 d、9 d、18 d、35 d、54 d和6月龄小鼠睾丸组织cDNA与Affymetrix全基因组芯片进行杂交,筛选出差异表达的基因。通过RT-PCR分析差异表达基因在小鼠睾丸不同发育阶段中的表达。结果分析Affymetrix全基因组芯片杂交结果后,筛选得到1个差异表达杂交点,通过在NCBI网站与小鼠全基因组序列Blast分析可知该差异表达基因是Rfx2基因。该基因在4 d、9 d、18 d、35d、54 ...
王朝亮 +7 more
doaj
Study of Pelo deficiency mediated antiviral activity [PDF]
果蝇是研究抗病毒天然免疫以及病毒与宿主相互作用的理想模型。我们以果蝇C病毒(DrosophilaCVirus,DCV)为病原体对已有的突变体果蝇库进行筛选,找到了一个对DCV感染更为抵抗的果蝇株并鉴定出其体内Pelo基因的表达量下降。通过基因敲除和表型回复实验,我们证实了Pelo基因的缺失的确可以使果蝇对DCV的感染更为抵抗。此外,DCV以及其他多种病毒的复制在Pelo基因敲除型果蝇中都变慢,说明Pelo基因缺陷可能介导了广谱的抗病毒免疫。 我们研究发现,Pelo并不参与目前已知的果蝇抗病毒免疫途径 ...
吴秀榕
core
ABSTRACT The development of high‐performance and stable electrocatalysts for oxygen reduction reaction (ORR), oxygen evolution reaction (OER), and hydrogen evolution reaction (HER) plays a critical role in advancing clean energy technologies, including metal‐air batteries and hydrogen production through overall water splitting.
Chen‐Yu Cai +4 more
wiley +1 more source
【目的】探讨载脂蛋白E(apolipoprotein E,ApoE)基因多态性与广州市中老年人群血脂水平的关系,以期为进一步研究提供基础和线索。【方法】采用等位基因特异性多重聚合酶链反应(ARMS-PCR)技术对624名40~65岁广州居民进行ApoE基因多态性检测,分析人群ApoE基因频率分布特点,并比较分析不同ApoE基因型血脂水平的关系。【结果】共检出6种基因型,以E3/3型最为常见,占67.95%,其次是E2/3和E3/4,分别占14.74%和13.62%,E2/4、E4/4和E2 ...
孙丽娜 +6 more
doaj
Sfmbt2 10th intron hosted microRNA-669e-5p/3p promote cellular apoptosis by targeting anti-apoptotic gene Bcl2 [PDF]
细胞凋亡是一个主动的由基因决定的自动结束生命的过程,对有机体的正常运行和体内稳态有重要作用。细胞凋亡一旦受到抑制,很可能导致肿瘤发生。然而,肿瘤发生发展过程中细胞凋亡调控的有关机制还不完全清楚。microRNAs(miRNAs)是一类非编码的小分子RNA,它们具有调节基因表达活性的功能,在细胞的各个进程(如细胞凋亡,分化和发育中)发挥着重要的作用。在肿瘤中miRNAs有可能通过调节与凋亡相关基因的表达,参与肿瘤细胞凋亡的调控。 miR-669e-5p和miR-669e ...
王涛
core
ABSTRACT The evolution of the γ′−Ni3(Al, Ti) phase in superalloys is governed by a coupled coalescence‐ripening mechanism driven by elemental diffusion. In this study, thermal exposure experiments were performed at 750°C and 800°C for durations ranging from 100 to 20,000 h.
Zhaotian Wang +5 more
wiley +1 more source
HBV-DNA高水平孕妇的HBV 前S和S区基因突变及基因分型
【目的】 研究HBV-DNA高水平孕妇的HBV前S(前S1和前S2)及S区的基因突变模式和基因分型,为从病毒因素探讨HBV母婴传播免疫阻断失败提供实验基础【方法】 选取血清HBsAg阳性且HBV-DNA≥105 IU/ mL的孕妇41 例,提取血清HBV-DNA,靶向设计HBV各基因型的前S及S区通用引物, 经PCR 扩增测序进行序列分析, 检测和分析前S及S区基因的突变情况,并进行基因分型【结果】 ①在 41 例样本中, 共有29例( 70.73%)样本存在前S1前S2及S区基因突变 ...
doaj
细胞毒性T 淋巴细胞相关抗原4 基因型与中国南方人群Graves ’ 病的关系
【目的】探讨细胞毒性T淋巴细胞相关抗原-4(cytotoxic T lymphocyte associated antigen 4)基因第一外显子A/G(49)多态性与中国南方汉族人群Graves′病的关系。【方法】用PCR-RFLP确定CTLA-4基因第1外显子49位点基因型,分析广东地区汉族人Graves′病患者(GD组)120例及123名正常人(对照组)CTLA-4基因多态性。并把GD患者按性别、家族史、TRAb、突眼等分别分两亚组后分析CTLA-4基因第1外显子A49G位点基因型及等位基因的频率。
姚斌 +4 more
doaj
Interface Issues of Inorganic Solid‐State Electrolytes in Secondary Magnesium Batteries
ABSTRACT Solid‐state magnesium batteries (SSMBs) have gained significant attention as promising candidates for next‐generation safe energy storage systems because of the abundance of magnesium (Mg) in the earth's crust, superior energy density, and inherent nonflammability.
Jiren Wang +9 more
wiley +1 more source

