Results 81 to 90 of about 36,876 (177)
白细胞介素8和载脂蛋白E基因多态性与迟发性 阿尔茨海默病的相关分析
Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 探讨白细胞介素8基因(interleukin-8,IL-8)基因A-251T和载脂蛋白E(ApoE)基因多态性与迟发性阿尔茨海默病(LOAD)的相关性65377;【方法】 采用聚合酶链反应-限制性片段长度多态性方法(PCR-RFLP)观察185例广东汉族人群 (研究组:LOAD患者88例,正常对照组97例) IL-8基因A-251T基因65380;ApoE基因多态性的分布并进行关联分析65377;【结果】 ① IL-8 基因A ...
doaj
麻疯树(Jatropha curcas)毒蛋白curcin基因家族成员的分离和描述
四川大学学报. 自然科学版, 2005 麻疯树curcin基因家族中4个成员通过PCR扩增被分离.它们都不含有内含子,序列分析表明它们编码Ⅰ型核糖体失活蛋白(Ribosome-Inactivating Proteins,RIPs),证明curcin基因如同大多数RIPs一样由多基因家族编码.四个curcin基因家族成员和另两个已知curcin基因家族成员的开放阅读框(Open Reading Frame,ORF)的序列比对结果显示curcin基因家族成员至少可分为两个亚类群,亚类群之间的氨基酸序列相似性低于88 ...
张金平, 秦小波, 徐莺, 陈放
doaj
Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT In Co‐based alloys, the γ phase is normally stable at high temperatures and the ε phase at low temperatures, and there is a martensitic transition on cooling to ∼417°C. In the γ/β dual‐phase CoCrAlY bond coat of turbine blade thermal barrier coating systems, we observed the opposite: γ remained stable at room temperature, yet it underwent a γ →
Junkai Liu +8 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2016 摘 要: 【目的】 分析鼻咽癌全基因组基因甲基化状态,筛选鼻咽癌颈淋巴结转移相关的甲基化基因?【方法】 收集I期(T1N0M0)鼻咽癌石蜡标本及有颈部淋巴结转移的鼻咽癌组织标本(T1-4N1-3M0)各4例,分别提取DNA,富集两组样品基因组甲基化片段后采用甲基化芯片对两组标本进行高通量测序分析,对杂交信号进行扫描及初步数据处理,分析并筛选出两组标本的差异甲基化基因?
doaj
Zhongguo shiyan zhenduanxue, 2012 肿瘤是一类细胞周期疾病,是多基因长期共同作用的结果。抑癌基因是指能够抑制细胞癌基因活性的一类基因,其功能是抑制细胞周期,阻止细胞数目增多以及促使细胞死亡。p 16基因是新近发现的抑癌基因,它以甲基化、突变或缺失等异常形式广泛存在于各种肿瘤患者中 ...
尹凤媛
doaj
Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT Due to their exceptional porosity, structural versatility, and modular coordination chemistry, metal–organic frameworks (MOFs) have emerged as versatile platforms for targeted drug delivery. These structures enable fine‐tuning of pore size, surface activity, and framework stability for the encapsulation of a broad range of therapeutics ...
Rui Hua +9 more
wiley +1 more source
糖尿病、冠心病患者ABCA1基因R219K多态性的频率分布特点
Zhongguo shiyan zhenduanxue, 2011 目的旨在探讨我国北方地区汉族人ABCA1基因R219K多态性的频率分布特点,对血脂水平的影响,及其与冠心病、糖尿病和糖尿病合并冠心病的关系。方法采用改良碘化钠法提取基因组DNA,聚合酶链反应限制性片段长度多态性（PCR-RFLP）法分析ABCA1基因R219K多态性。结果正常对照组ABCA1基因R219K多态性RR、RK、KK基因型频率、R等位基因频率、K等位基因频率分别为28.5%、48.6%、22.9%、52.8%、47.2%;糖尿病组分别为29.6%、63.9%、6.5%、61.5%、38.5 ...
许慧, 彭浩, 蒋莹
doaj
Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT Ultrathin, lightweight, and mechanically compliant electromagnetic interference (EMI) shields are increasingly required for high‐frequency electronic devices. However, conventional metallic shields predominantly rely on conductivity‐driven reflection mechanisms, which become ineffective at reduced thickness and may cause severe secondary ...
Zida Zhang +7 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2015 目的探讨脂联素基因多态性与妊娠期糖耐量受损相关性。方法选取2013年2月-2014年2月我院收治的妊娠期糖尿病患者共60例,以及选取同期我院体检糖耐量正常的孕妇共60例,采用聚合酶链反应-限制性片段长度多态性（PCR-RFLP）技术分析脂联素基因多态性位点（+276G/T、+45T/G、-3971A/G）。结果脂联素基因、276、+45位点的等位基因频率经过Hardy-Weinberg遗传平衡定律检验指出各基因频率已达遗传平衡（P>0.05）。两组的脂联素基因+276G/T等位基因、基因型频率分布对比 ...
栾媛媛, 郭晓辉, 杨俊红
doaj
Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT Fast‐charging capability is one of the crucial factors determining the application prospects of sodium‐ion batteries (SIBs). Nevertheless, the mismatched sodium storage kinetics and Coulombic efficiency (CE) in hard carbon anodes are bottlenecks in the implementation of fast‐charging SIBs. Herein, we propose a facile pre‐carbonization strategy
Qixin Liu +8 more
wiley +1 more source