Results 11 to 20 of about 16,209 (168)
In vitro culture, cryopreservation, and field reintroduction of the endangered Mingan thistle
Abstract Current plant conservation efforts are hindered by, for example, poor seed germination, low viability, and insufficient propagation and preservation technologies. To address these problems, we devised an approach to plant conservation that integrates conservation, preservation, and restoration (CPR), which uses advanced in vitro techniques. We
Mukund R. Shukla +4 more
wiley +1 more source
Effects of parachute science on local research capacity 降落伞科学对当地研究能力的影响
Abstract Strengthening research capacity is essential to address the global biodiversity crisis. Yet, parachute science often undermines this goal, and its prevalence, costs, and benefits are unclear. We analyzed 13,502 publications on primate research that we extracted from Scopus (1960–2022) to evaluate the effects of parachute science on local ...
Li Yang +11 more
wiley +1 more source
Abstract Human development is a driver of global change and a major threat to biodiversity. Protected areas maintain and support biodiversity, but outside stressors, such as climate change and land use change, can negatively influence natural resources within protected areas.
Leah J. Rudge +2 more
wiley +1 more source
Poly I∶C and R848 Induce Cell Proliferation in the Intact Rat Spinal Cord [PDF]
目的研究Poly I∶C与R848对脊髓细胞增殖的诱导效应。方法大鼠单次腹腔注射(ip)Poly I∶C与R848,增殖的细胞由BrdU跟踪标记。结果Poly I∶C与R848可引起大鼠脊髓BrdU+细胞明显增加,于注射后2~3 d达最高,随后快速降至正常水平,同时可见BrdU+/Nestin+细胞存在,并伴小胶质细胞的活化,未见有ED-1+/BrdU+的细胞。地塞米松可抑制细胞增殖及小胶质细胞活化,而消炎痛无此作用。结论配体被TLR识别后可能参与脊髓内正常神经细胞的发生过程 ...
吕姝焱, 徐顺清, 苏艳华
core
ABSTRACT Against the backdrop of calling for nonfemale‐oriented promotion of vaccination against human papillomavirus (HPV), this study explored three potential names—“HPV Vaccine,” “Cervical Cancer Vaccine,” and “Genital Warts Vaccine”—to promote vaccination against HPV infection among heterosexual men.
Timothy K. F. Fung +2 more
wiley +1 more source
The Role and Mechaninsm study of IL-20-related Cytokines contribute to Autoimmune Myocarditis in Mice [PDF]
目的:免疫相关因素与心肌炎引起的心肌纤维化密切相关。前期研究表明,IL-10家族成员在心肌炎慢性期心肌纤维化的形成过程中发挥重要作用。IL-20是最新发现的IL-10家族成员之一,具有调节细胞增殖和分化的作用。但IL-20是否参与心肌炎心肌纤维化过程尚不清楚。本课题通过实验探讨IL-20及其相关因子对小鼠自身免疫性心肌炎(EAM)心肌纤维化的影响及可能的分子调节机制。 方法:利用小鼠心肌肌球蛋白多肽MyHC6l4-629和完全弗氏佐剂充分混合后,于第0天和第7天皮下注射建立小鼠EAM模型;组织切片H ...
许俊铭
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ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu +13 more
wiley +1 more source
原发性肝癌属于常见的恶性肿瘤,临床发病率与死亡率均较高。特别是肝炎病毒感染,是诱发原发性肝癌的重要因素。目前阶段,国内以乙型肝炎病毒为主,在单染病毒感染后,会严重损伤肝脏,导致干细胞半持续性增殖[1]。一旦细胞增殖速度加快,就会增加干细胞增殖周期当做调控基因的改变几率[2 ...
史立英 +4 more
doaj
Mechanistic Analysis of Immunomodulation by Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells in Mice [PDF]
背景:间充质干细胞是具有自我更新能力和分化能力的组织细胞前体细胞,能够分化为一系列的间质细胞,包括成骨细胞、成软骨细胞、脂肪细胞、肌细胞和内皮细胞等。细胞治疗是再生医学发展的一个重要分支。越来越多的研究发现,间充质干细胞能够修复组织损伤,达到一定治疗效果。因此,间充质干细胞被视为天然组织工程材料的重要种子细胞,具有广阔的应用前景。此外,间充质干细胞具有负性免疫调节能力。在体外共培养条件下,间充质干细胞能够抑制免疫细胞功能,包括抑制T细胞反应,抑制树突状细胞的成熟和抗原提成,抑制B细胞激活和增殖 ...
李成林
core
ABSTRACT The study by Morshed‐Behbahani et al. highlights that financial barriers are not the sole obstacle to accessing infertility treatment. To ensure equal access for all, infertility treatment should be regarded as a universal human right, with the public sector assuming responsibility for its provision.
Arturs Kalva, Girts Brigis
wiley +1 more source

