Results 41 to 50 of about 16,209 (168)
Shuitu Baochi Xuebao, 2020 为了探索腐殖酸对土壤水盐运移特征及入渗参数的影响，进行了5种施量（0，1，3，5，7 g/kg）的一维垂直入渗试验。结果表明，入渗时间相同，累积入渗量和湿润锋均随腐殖酸施量的增加而减小；相同入渗深度随腐殖酸施量的增加所需的入渗时间、累积入渗量、剖面平均含水量均不断增加。入渗完成时相较于CK，施量为7 g/kg时累积入渗量、含水量分别增加8.0%，10.0%；施加腐殖酸可促进土壤剖面盐分向土壤深层运移并有效降低土壤pH，相较于CK施量为7 g/kg时0—20 cm土层平均脱盐率增加10.2 ...
李晓菊 +4 more
doaj
The mechanism and function of extracellular matrix protein Mindin in the colon cancer progression [PDF]
, 2015 在世界范围内，结直肠癌是临床上常见的恶性肿瘤之一。结肠癌的发病机制也在不断细致、深入的研究。然而结肠癌这种实体肿瘤不像单纯的肠癌细胞系。相反，它是由多种类型的细胞和细胞外基质组成的功能失调的器官。细胞外基质是肿瘤微环境的重要组成部分，包含各种各样的细胞因子和代谢产物，具有向细胞传导各种环境信号的作用。这些信号对于细胞生命过程的方方面面都必不可少，包括增殖、分化和死亡等。然而，细胞外基质蛋白在结肠癌发生发展的演变过程中的作用尚未完全明确。 分泌型的细胞外基质蛋白Mindin作为Mindin-F ...
肖传兴
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New Phytologist, Volume 247, Issue 3, Page 1117-1128, August 2025.Summary Environmental changes and their effects are among the most pressing topics of today's ecological research. Shrublands, although widespread across the globe, remain understudied in this respect. We conducted a global meta‐analysis of 81 shrubland sites subjected to experimental warming, shifts in precipitation (e.g.
Daijun Liu +11 more
wiley +1 more source
Yap Regulates ATF6-Mediated Unfolded Protein Response [PDF]
, 2015 Hippo信号通路最早在果蝇里发现，是在进化上高度保守的一条激酶级联的通路，当Hippo通路的缺失会造其下游调控因子Yap或Taz的激活，促进细胞增殖，抑制细胞凋亡，从而导致器官增大和肿瘤产生。此外，大量文献阐述了内质网压力和肿瘤产生具有相关性。本实验室研究表明，Hippo通路的缺失或Yap蛋白的激活会引起内质网应激信号通路的激活和内质网的增大，并通过内质网应激反应导致肝脏器官增大和肿瘤生成。 当Hippo激酶，在高等动物的同源物为Mst1和Mst2激酶的缺失或Yap激活时 ...
蔡亚波
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New Phytologist, Volume 247, Issue 2, Page 504-517, July 2025.Summary Repetitive DNA is a feature of all organisms, ranging from archaea and plants to humans. DNA repeats can be seen both in coding and in noncoding regions of the genome. Due to the recurring nature of the sequences, simple DNA repeats tend to be more prone to errors during replication and repair, resulting in variability in their unit length ...
Sridevi Sureshkumar +3 more
wiley +1 more source
曲列格酮对Hep G2肝癌细胞增殖、COX-2表达和前列腺素E2水平的影响
Zhongguo shiyan zhenduanxue, 2003 目的 探讨曲列格酮 （TGZ）对HepG2肝癌细胞增殖的影响。方法 TGZ处理HepG2细胞后 ,用MTT、[3 H]-胸苷摄入、Northern杂交、RT -PCR、Western印迹等方法分别测定细胞增殖、COX - 2表达及PGE2水平。结果 TGZ以剂量依赖方式抑制细胞增殖 ,并下凋COX - 2表达及抑制PGE2产生。结论 TGZ抑制HepG2肝癌细胞增殖 ,这种抑制作用可能与COX - 2表达减少有关。
李明意 +4 more
doaj
A study about the impact of overpression of Oct4 and Sox2 gene on gastric cancer cell biology and oncology characteristics [PDF]
, 2015 目的：通过构建过表达干细胞因子Oct4和Sox2的胃癌SGC7901细胞株，研究过表达干细胞因子Oct4和Sox2对SGC7901胃癌细胞干细胞特性、肿瘤学特性、及生物学特性的影响，并探讨Oct4及Sox2在肿瘤细胞中的作用机制。 方法：1.构建携带Sox2基因的重组质粒，慢病毒载体感染SGC7901-OCT4细胞株得到SGC7901-OCT4-SOX2稳转细胞株。2.利用荧光定量PCR、western–bloting检测过表达Oct4及Sox2的胃癌SGC7901细胞中胃癌干细胞标志基因表达情况。3 ...
李文鹏
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Wildlife Letters, Volume 3, Issue 2, Page 64-72, June 2025.Daily survival rate of active nests (with parental care) (n = 30) and the same inactive nests after breeding had finished (without parental care) (n = 30) of the White‐bellied Redstarts during the incubation period; the orange line represents inactive nests and the blue line represents active nests at the same site.
Yifei Wang +5 more
wiley +1 more source
HUVECs Promote the Proliferation of iPS-MSCs by FAM3B [PDF]
, 2016 间充质干细胞（mesenchymalstemcells，MSCs）存在于一个血管周微环境中，在这个微环境内，内皮细胞（endothelialcells，ECs）与MSCs互相作用，调控MSCs的表型和增殖，从而在MSCs的血管生成作用和治疗应用方面起重要作用。然而，MSCs受到来源、年龄、健康等多方面的影响，不能满足大规模的使用需求。诱导多能干细胞来源的间充质干细胞（inducedpluripotentstemcell-derivedMSCs，iPS-MSCs）可能会是一个有前景的替代性干细胞来源。但是，
冷云
core
Using camera traps to enhance community‐based management of subsistence hunting in the Amazon
Conservation Biology, Volume 39, Issue 3, June 2025.Abstract Community‐based management and monitoring of biodiversity has emerged as a cost‐effective strategy for providing credible data, informing decision‐making, and empowering local communities in resource governance and management. However, the establishment of community‐based management of subsistence hunting in the Brazilian Amazon has been ...
Ricardo Sampaio +3 more
wiley +1 more source