Zhongguo shiyan zhenduanxue, 2003 目的 探讨儿童持续性蛋白尿与血管紧张素转换酶基因多态性的关系。方法 用PCR方法检测了 186例儿童持续性蛋白尿患儿ACE基因多态性及ACE基因多态性与尿蛋白量、血尿、高血压、氮脂血症的关系。结果 持续性蛋白尿患儿ACE -DD基因频率为 0 .2 0 ,II基因频率为 0 .5 2 ,DI基因频率为 0 .2 8;持续性蛋白尿患儿ACE基因多态性与正常对照组存在明显差异 ;尿蛋白量与ACE基因多态性有关 ,大量蛋白尿多为ACE -II型 ;在紫癜性肾炎组血尿的发生以II型为主 ...
李丽红 +5 more
doaj
Molecular cloning, expression of heat shock protein 60 (HSP60) gene in Marsupenaeus japonicus and the association of its polymorphisms with thermal tolerance [PDF]
, 2015 日本囊对虾(Marsupenaeusjaponicus)是我国重要经济养殖虾类，但其在南方地区存在着高温度夏死亡率较高的养殖难题。因此，急需了解日本囊对虾的耐热性状及耐温的分子机制，为此，我们开展了日本囊对虾MjHSP60基因的克隆、表达分析及其多态性与耐热性状相关性的研究，获得了如下主要结果： 1.MjHSP60基因克隆 在日本囊对虾MjHSP60cDNA序列基础上克隆到了该基因DNA全序列。日本囊对虾MjHSP60基因全长4055bp，结构与拟穴青蟹一致，均由8个外显子及7个内含子构成 ...
李丽君
core
Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
Rare Metals, EarlyView.ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2012 目的探讨原发性肝细胞癌人群中谷胱甘肽巯基转移酶基因多态性与肝癌发生、发展的关系。方法我院2008年10月-2010年4月收治的原发性肝癌患者与健康体检者各150名,提取血样,利用多重PCR和限制性片段长度多态性检测法分别检测肝癌人群与体检健康者的谷胱甘肽巯基转移酶基因多态性,并进行对比分析。结果该肝癌人群中:谷胱甘肽巯基转移酶基因多态性型别在病例和对照组研究对象中出现的频率无显著性差别,P>0.05;GSTM1-null、GSTT1-null、GST01-Ala140Asp、GSTP1 ...
唐耘天 +5 more
doaj
MXene‐Based Electromagnetic Attenuation Materials in Microwave and Terahertz Bands
Rare Metals, EarlyView.ABSTRACT MXenes exhibit considerable potential for developing high‐performance electromagnetic (EM) shielding and absorption materials operating across microwave and terahertz frequencies, due to their tunable surface chemistry and exceptional charge carrier transport properties.
Guozheng Zhang +9 more
wiley +1 more source
E-选择素基因rs3917422A和rs5355C位点多态性与哈尼族原发性高血压相关性研究
Zhongguo shiyan zhenduanxue, 2009 目的探讨E-选择素基因rs3917422A\C和rs5355C\T位点多态性与哈尼族原发性高血压的关系。方法采用PCR测序技术,对云南哈尼族172例原发性高血压患者和133例正常对照的E-选择素基因rs3917422A\C和rs5355C\T的错义突变进行检测。结果在哈尼族中未发现有rs3917422A多态存在,发现rs5355C基因有多态存在。rs5355C等位基因频率在原发性高血压组中为10.5%,正常对照组中为13.2%,两组之间无显著性差异（P=0.311,P>0.05）。结论哈尼族中E ...
黎曼侬 +6 more
doaj
Screening of SNP Loci of Growth-related Candidate Gene and Genetic Diversity of Five Populations Based On Microsatellite Markers in Fujian Oyster, Crassostrea angulata [PDF]
, 2015 福建牡蛎(Crassostreaangulata，C.angulata)又名葡萄牙牡蛎，具有重要的经济价值和生态价值，但由于长期未经选育以及人工育苗的应用，导致牡蛎养殖出现经济性状衰退及死亡率逐年增高等现象，亟需加强种质资源保护，开展遗传改良研究。本研究利用单核苷酸多态性分子标记（singlenucleotidepolymorphism，SNP）对福建牡蛎生长相关的5个候选基因，即胰岛素相关多肽（insulinrelatedpeptides，IRPs）、ɑ-淀粉酶（ɑ-Amylase，ɑ-AMY ...
楚瑞敏
core
Giant Tunability of Individual Magnetic Skyrmion Size via an Oscillating Local Magnetic Field
Rare Metals, EarlyView.ABSTRACT Magnetic skyrmions hold great promise as memory and computing elements in future spintronic devices. Despite the demonstration of various devices, techniques for addressable and high‐precision manipulation of individual skyrmions remain scarce.
Cai‐Hong Xie +13 more
wiley +1 more source
Investigation of the association between adult intelligence and Apolipoprotein E genotype in the young Chinese Han population [PDF]
, 2015 载脂蛋白E（ApolipoproteinE）在脂质代谢及分布中具有重要作用。载脂蛋白E基因具有多态性，包含了APOEɛ2、APOEɛ3和APOEɛ4三种。其中，ɛ4等位基因是引起迟发型阿尔茨海默病（Late-onsetAlzheimer’sDisease）最重要的危险因素。尽管许多研究表明在老年人中APOE基因的多态性与认知功能密切相关，但其对青年人认知功能的影响研究非常少，并且有限的研究结果存在争议性。为了进一步探讨APOE基因多态性对青年人认知功能的影响 ...
魏孜辰
core
Rare Metals, EarlyView.ABSTRACT Organic‐inorganic hybrid perovskites (OIHPs) with white‐light emission have significant potential in solid‐state lighting and display due to the designable structure and excellent luminescent properties. However, OIHPs are prone to damage during bending due to the brittleness of crystals, which limits their application in the field of flexible
Jinyu Xu +8 more
wiley +1 more source