Results 91 to 100 of about 1,489 (154)

知母皂苷元对体外培养皮层神经元树突发育的影响及信号转导机制 [PDF]

目的探讨知母皂苷元(Sarsasapogenin,SAR)对大脑皮层神经元树突发育的促进作用及其信号转导机制。方法选用出生0～24 h的Sprague-Dawley(SD)大鼠乳鼠,取皮层神经元进行体外细胞培养,4 d后用于实验。倒置相差显微镜测量培养神经元树突分支总长度(TDBL)、一级树突数目(PDN)、最大分支级数(MBO)和神经元胞体面积。West-ern blot法观察神经元p-PDK1、p-Akt473及p-mTOR蛋白表达。结果形态学观察结果显示SAR(10、30、100μmol.L-1 ...
张永兴, 王金宁, 董燕, 隋海娟
core  

长时程睡眠剥夺对大鼠行为记忆和海马区递质的影响及四神聪电针的预防作用

Zhongshan Daxue xuebao. Yixue kexue ban, 2018
【目的】探讨连续长时程睡眠剥夺对大鼠行为、记忆和海马区递质的影响及四神聪电针的预防作用。 【方法】采用多平台法进行连续7 d睡眠剥夺造模。实验分阶段进行，一阶段（实验一）：将30只SD雌性大鼠随机分 成环境对照组（TC组），睡眠剥夺组（SD组），睡眠剥夺结束后3 d组（3 d after SD）、6 d组（6 d after SD）和11 d组（11 d after SD），即7 d睡眠剥夺结束后再在常规大鼠饲养笼内饲养不同时间，并让大鼠恢复正常睡眠；每组大鼠均为6 只 ...
李志铃, 汪燕玲, 阮经文
doaj  

[Yigong San improves learning and memory functions of APP/PS1 transgenic mice by regulating brain fluid metabolism]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zeng J, Hua L, Yang Y, Zhang X, Wei J, Li L.   +5 more
europepmc   +1 more source

褪黑素对不同年龄SAM-P8小鼠学习记忆相关脑区的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 2014
摘 要: 【目的】 研究褪黑素的短期干预对不同年龄SAM-P8脑内膈隔-海马胆碱能系统和海马结构退变的影响?【方法】 选用SAM-P8鼠36只,分为中年低?高浓度治疗组(ME1G?ME2G),老年低?高浓度治疗组(AE1G?AE2G)及其相应的对照组ACG?MCG),共6组?中年?老年治疗组分别于小鼠4月龄?7月龄时每日皮下注射褪黑素(5 mg或10 mg/kg)30 d?对照组注射相同剂量的生理盐水,给药结束后继续饲养到11月龄,采用跳台试验测试其学习及记忆能力 ...
doaj  

[ResLSTM-TemporalSE: an automated classification model for multi-lead ECG signals]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Qu M, Fu R.
europepmc   +1 more source

[Effects of 40 Hz light flicker stimulation on hippocampal-prefrontal neural activity characteristics during working memory tasks in Alzheimer's disease model rats]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Liu S, Wang L, Li S, Xu G.
europepmc   +1 more source

[Evaluation of an interpretable 12-lead ECG automatic diagnosis model based on deep feature fusion]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Lu X, Chen H, Wu Q, Wen Y, Liu G, Chen C.   +5 more
europepmc   +1 more source

[<i>Qixiong Zuogui</i> Granules enhance synaptic plasticity in aging rats by regulating the BDNF/TrkB signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wang Q, Zhao X, He Y, Liu F, Zhang Y.
europepmc   +1 more source

[The application of machine learning in the auxiliary diagnosis of specific learning disorder]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Zhao H, Mei SL, Wang JY, Chi X.
europepmc   +1 more source

[Development and validation of a risk prediction model for cognitive impairment in rural elderly Chinese populations: evidence from the CHARLS study]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wang F, Li W, Shang X, Li F.
europepmc   +1 more source